[1]洪小康,武倡臣,黄新源,等.颅内破裂动脉瘤栓塞术后并发吉兰-巴雷综合征1例[J].中国临床神经外科杂志,2024,29(03):187-189.[doi:10.13798/j.issn.1009-153X.2024.03.015]
　HONG Xiao-kang,WU Chang-chen,HUANG Xin-yuan,et al.A case of Guillain-Barré syndrome after embolization of ruptured intracranial aneurysm[J].,2024,29(03):187-189.[doi:10.13798/j.issn.1009-153X.2024.03.015]
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颅内破裂动脉瘤栓塞术后并发吉兰-巴雷综合征1例()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
29
期数:
2024年03期
页码:
187-189
栏目:
个案报道
出版日期:
2024-03-31

文章信息/Info

Title:
A case of Guillain-Barré syndrome after embolization of ruptured intracranial aneurysm
文章编号:
1009-153X（2024）03-0187-03
作者:
洪小康; 武倡臣; 黄新源; 关锋; 王凡
550001贵阳，贵州医科大学临床医学院（洪小康）；550014贵阳，贵州医科大学附属白云医院神经外科（武倡臣、黄新源、关锋、王凡）
Author(s):
HONG Xiao-kang1;  WU Chang-chen2;  HUANG Xin-yuan2;  GUAN Feng2;  WANG Fan2
1. School of Clinical Medicine, Guizhou Medical University, Guiyang 550001, China; 2. Department of Neurosurgery, Baiyun Hospital affiliated to Guizhou Medical University, Guiyang 550014, China
关键词:
颅内破裂动脉瘤; 血管内栓塞; 吉兰-巴雷综合征
Keywords:
Ruptured intracranial aneurysms;  Endovascular embolization;  Guillain-Barré syndrome
分类号:
R 734.9; R 815.2
DOI:
10.13798/j.issn.1009-153X.2024.03.015
文献标志码:
B
摘要:
吉兰-巴雷综合征（GBS）是一种自身免疫性神经疾病，主要特征是四肢无力和肌张力减低。颅内破裂动脉瘤栓塞术后出现肢体肌力下降一般认为是症状性血管痉挛，通常发生在术后4~10 d。本文报道1例55岁男性左侧颈内动脉C6段破裂动脉瘤，血管内栓塞术后12 d突然出现渐进性四肢无力，四肢肌张力减低、腱反射消失，完善神经传导检查、脑脊液病毒抗体、血清周围神经抗体检查等检查确诊GBS。予以免疫球蛋白治疗后康复出院，7个月随访恢复正常。这提示颅内破裂动脉瘤栓塞术后脑血管痉挛期出现无明确病因的四肢肌力减退时，应当考虑到GBS，早期诊断对于避免延误病情和及时治疗非常重要。
Abstract:
Guillain-Barré syndrome (GBS) is an autoimmune neurological disorder characterized by weakness and decreased muscle tone in the limbs. The decrease in limb muscle strength that occurs after endovascular embolization for ruptured intracranial aneurysms is generally considered symptomatic vasospasm, usually occurring 4~10 days after surgery. This article reports a case of a 55-year-old male with a ruptured aneurysm at the C6 segment of the left internal carotid artery who suddenly developed progressive limb weakness, decreased muscle tone in all limbs, and absent tendon reflexes 12 days after endovascular embolization. The diagnosis of GBS was confirmed by comprehensive neurological examinations, cerebrospinal fluid viral antibody testing, and serum peripheral nerve antibody testing. The patient recovered and was discharged after receiving immunoglobulin therapy, and normal recovery was observed during a 7-month follow-up. This suggests that when limb muscle weakness without a clear cause occurs during the cerebral vasospasm period after endovascular embolization of ruptured intracranial aneurysms, GBS should be considered, and early diagnosis is crucial for preventing the delay of the disease's diagnosis and enabling timely treatment.

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备注/Memo

备注/Memo:
（2023-05-25收稿，2023-10-30修回）
通信作者：王　凡，Email：1034309115@qq.com
更新日期/Last Update: 2024-03-31