参考文献/References:
[1] Ostrom QT, Gittleman H, Liao P, et al. CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2010~2014 [J]. Neuro Oncol, 2017, 19(5): 1-88.
[2] Raj S, Pandit PN, Kishor K. A retrospective comparative study of concomitant chemoradiotherapy followed by adju-vant temozolomide versus radiotherapy alone in newly diagnosed glioblastoma multiforme-an experience at radiuminstitute, patna medical college and hospital, India [J]. Gulf Joncolog, 2016, 1(20): 6-11.
[3] 沈亦雯，朱剑虹. 胶质瘤的细胞起源[J]. 中国临床神经科学，2016，24（4）：462-469.
[4] 罗林明，姜懿纳，陈乃宏. 神经干细胞对胶质瘤发生发展影响的研究进展[J]. 神经药理学报，2015，5（5）：28-33.
[5] Capilla-Gonzalez V, Lavell E, Quinones-Hinojosa A, et al. Regulation of subventricular zone-derived cells migration in the adult brain [J]. Adv Exp Med Biol, 2015, 853(1): 1-21.
[6] Homem C, Repic M, Knoblich JA. Proliferation control in neural stem and progenitor cells [J]. Nat Rev Neurosci, 2015, 16(3): 647-659.
[7] Macas J, Ku MC, Nern C, et al. Generation of neuronal pro-genitor cells in response to tumors in the human brain [J]. Stem Cells, 2014, 32(2): 244-257.
[8] Bardella C, Al-Shammari AR, Soares L, et al. The role of inflammation in subventricular zone cancer [J]. Prog Neuro-biol, 2018, 170(1): 37-52.
[9] Sharma A, Shiras A. Cancer stem cell-vascular endothelial cell interactions in glioblastoma [J]. Biophys, 2016, 473(7): 688-692.
[10] Chen J, Li Y, Burns DK, et al. A restricted cell population propagates glioblastoma growth after chemotherapy [J]. Nature, 2012, 488(4): 521-522.
[11] Bao S, Wu Q, McLendon RE, et al. Glioma stem cells pro-mote radioresistance by preferential activation of the DNA damage response [J]. Nature, 2006, 444(6): 756-760.
[12] 庞 晶，胡辛欣，王跃明，等. 新型抗肿瘤微管抑制剂IG-105的体外代谢及药物相互作用的研究[J]. 药学学报，2017，52（6）：921-927.
[13] Dragu DL, Necula LG, Bleotu C, et al. Therapies targeting cancer stem cells: current trends and future challenges [J]. Stem Cells, 2015, 7(11): 1182-1185.
[14] 陈名宇，吴婷婷，任振华. 胶质瘤干细胞表面标志物的研究进展[J]. 中国临床神经外科杂志，2018，23（4）：299-301.
[15] Beier D, Hau P, Proescholdt M, et al. CD133+ and CD133- glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles [J]. Cancer Res, 2007, 67(5): 4010-4015.
[16] 孙连杰，麦麦提依明·托合提，杨小朋.与胶质瘤诊断及预后相关的分子标记物的研究进展[J]. 中国临床神经外科杂志，2018，23（9）：633-635.
[17] 刘梦昱，谢 飞，张 鑫，等. 胶质母细胞瘤相关分子标志物研究进展[J]. 生物技术进展，2019，9（2）：129-138.
[18] Rheinbay E, Wakimoto H, Shahid M, et al. An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma [J]. Cell Rep, 2013, 3(7): 1567-1579.
[19] 杨仁松，胡海燕. 神经干细胞增殖与分化的主要调控信号通路研究进展[J]. 神经解剖学杂志，2016，32（2）：272-276.
[20] Saito N, Fu J, Zheng S, Yao J, et al. A high notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumorinitiating cells [J]. Stem Cells, 2014, 32(2): 301-312.
[21] 罗斌华，荔志云. 血管生成拟态在胶质瘤中的研究进展[J]. 国际神经病学神经外科学杂志，2018，45（5）：510-515.
[22] Filatova A, Seidel S, Bogurcu N, et al. Acidosis acts throughHSP90 in a PHD/VHL-independent manner to promote HIF function and stem cell maintenance in glioma [J]. Cancer Res, 2016, 76(5): 5845-5856.
[23] Bao S, Wu Q, Sathornsumetee S, et al. Stem cell-like gliomacells promote tumor angiogenesis through vascular endothe-lial growth factor [J]. Cancer Res, 2006, 66(8): 7843-7848.
[24] Unterkircher T, Cristofanon S, Wirtz C, et al. Bortezomib primes glioblastoma including glioblastoma stem cells for TRAIL by increasing tBid stability and mitochondrial apoptosis [J]. Cancer Res, 2011, 7(12): 4019-4030.
[25] Nazio F, Bordi M, Cianfanelli V, et al. Autophagy and cancer stem cells: Molecular mechanisms and therapeutic applications [J]. Cell Death Differ, 2019, 26(3): 690-702.
[26] Sun R, Shen S, Wang J, et al. Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemothera-peutics against breast cancer stem cells [J]. Biomaterials, 2016, 103(1): 44-55.
[27] Buccarelli M, Marconi M, Pacioni S, et al. Inhibition of autophagy increases susceptibility of glioblastoma stem cellsto temozolomide by igniting ferroptosis [J]. Cell Death Dis, 2018, 9(8): 838-841.
[28] Hayes J, Thygesen H, Tumilson C, et al. Prediction of clini-cal outcome in glioblastoma using a biologically relevant nine-micro RNA signature [J]. Mol Oncol，2015, 9(3): 704-714.
[29] Glantz M, Kesari S, Recht L, et al. Understanding the originsof gliomas and developing novel therapies: Cerebrospinal fluid and subventricular zone interplay [J]. Semin Oncol, 2009, 36(1): 17-24.
[30] Piccirillo S, Zanetti N, Binda E, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumourinitiating cells [J]. Nature, 2006, 444(6): 758-761.
[31] Bezecny P. Histone deacetylase inhibitors in glioblastoma: pre-clinical and clinical experience [J]. Med Oncol, 2014, 31(7): 982- 985.
[32] Phuphanich S, Wheeler CJ, Mazer M, et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma [J]. Cancer Immunol, 2013, 62(1): 125-135.
[33] Johanns TM，Ferguson CJ，Grierson PM，et al. Rapid clinicaland radiographic response with combined dabrafenib and trametinib in adults with BRAF-mutated high-grade glioma[J]. J Natl Compr Canc Netw, 2018, 16(1): 4-10.
相似文献/References:
[1]谢宝树 张 林 王 宇 贾 锋 殷玉华.复发性多发胶质母细胞瘤的预后分析[J].中国临床神经外科杂志,2016,(06):333.[doi:10.13798/j.issn.1009-153X.2016.06.005]
XIE Bao-shu,ZHANG Lin,WANG Yu,et al.Analysis of prognoses in patients with recurrent multiple glioblastomas[J].,2016,(03):333.[doi:10.13798/j.issn.1009-153X.2016.06.005]
[2]宋贵东 综述 高之宪 审校.贝伐单抗治疗复发胶质母细胞瘤的研究进展[J].中国临床神经外科杂志,2015,(10):638.[doi:10.13798/j.issn.1009-153X.2015.10.022]
[3]李继强 杨吉安 邵灵敏 吴庭枫 刘宝辉 陈谦学.稳定低表达BAG3的胶质母细胞瘤U87细胞株的构建及鉴定[J].中国临床神经外科杂志,2015,(06):353.[doi:10.13798/j.issn.1009-153X.2015.06.011]
LI Ji-qiang,YANG Ji-an,SHAO Ling-min,et al.Construction and identification of U87 glioblastoma cell strain with a stable low expression of BAG3[J].,2015,(03):353.[doi:10.13798/j.issn.1009-153X.2015.06.011]
[4]桂志勇 冯 军 黄俊红 白敬洋.靶向沉默c-fos基因表达对胶质瘤U87MG细胞增殖与侵袭的影响[J].中国临床神经外科杂志,2017,(12):834.[doi:10.13798/j.issn.1009-153X.2017.12.011]
GUI Zhi-yong,FENG Jun,HUANG Jun-hong,et al.Effects of c-fos targeted silence on proliferation and invasiveness of human glioma cell U87[J].,2017,(03):834.[doi:10.13798/j.issn.1009-153X.2017.12.011]
[5]王娇燕 孟凡华 刘魏然 魏春晓 林丽萍.SWI在胶质母细胞瘤与单发脑转移瘤鉴别中的价值[J].中国临床神经外科杂志,2018,(01):13.[doi:10.13798/j.issn.1009-153X.2018.01.005]
WANG Jiao-yan,MENG Fan-hua,LIU Wei-ran,et al.Value of susceptibility-weighted imaging in differentiative diagnosis of glioblastomas and solitary brain metastases[J].,2018,(03):13.[doi:10.13798/j.issn.1009-153X.2018.01.005]
[6]张治元 王汉东 樊友武 贾 玥 吴晋蓉.胶质肉瘤15例分析及文献复习[J].中国临床神经外科杂志,2018,(02):69.
ZHANG Zhi-yuan,WANG Han-dong,FAN You-wu,et al.Diagnosis and treatment of gliosarcoma: a report of 15 cases and literature review[J].,2018,(03):69.
[7]郑锐哲 姜秀峰 陈二涛 孙兆良 冯东福.胶质母细胞瘤卒中术后继发硬膜下水瘤1例[J].中国临床神经外科杂志,2019,(02):128.[doi:10.13798/j.issn.1009-153X.2019.02.022]
[8]胡 玥,薛小燕,李子超,等.阿苯达唑抑制胶质瘤裸鼠模型肿瘤生长[J].中国临床神经外科杂志,2019,(06):348.[doi:10.13798/j.issn.1009-153X.2019.06.010]
HU Yue,XUE Xiao-yan,LI Zi-chao,et al.Albendazole inhibits tumor growth in nude mice model of glioma[J].,2019,(03):348.[doi:10.13798/j.issn.1009-153X.2019.06.010]
[9]殷安安 陆 南 贺亚龙 章 翔 刘玉河.TRIM38基因非CpG岛DNA甲基化与胶质母细胞瘤临床预后的关系[J].中国临床神经外科杂志,2020,(02):76.[doi:10.13798/j.issn.1009-153X.2020.02.005]
YIN An-an,LU Nan,HE Ya-long,et al.Impacts of TRIM38 non-CpG island DNA methylation alterations on clinical prognosis in patients with glioblastomas[J].,2020,(03):76.[doi:10.13798/j.issn.1009-153X.2020.02.005]
[10]吴 蛟 易 勇 赵卓琳 周良学 周世军.贝伐珠单抗联合化疗治疗胶质母细胞瘤的meta分析[J].中国临床神经外科杂志,2020,(02):82.[doi:10.13798/j.issn.1009-153X.2020.02.007]
WU Jiao,YI Yong,ZHAO Zhuo-lin,et al.Efficacy and safety of bevacizumab combined with chemotherapy for glioblastoma: a meta-analysis[J].,2020,(03):82.[doi:10.13798/j.issn.1009-153X.2020.02.007]