[1]祝　斐　颉　奎　饶　敏　黄　新　吴　明　金卫星　朱炯明.良性脑膜瘤术后复发的影响因素分析[J].中国临床神经外科杂志,2015,(02):90-92.[doi:10.13798/j.issn.1009-153X.2015.02.008]
　ZHU Fei,XIE Kui,RAO Min,et al.Analysis of factors related to postoperative recurrence of benign meningiomas[J].,2015,(02):90-92.[doi:10.13798/j.issn.1009-153X.2015.02.008]
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良性脑膜瘤术后复发的影响因素分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年02期
页码:
90-92
栏目:
论著
出版日期:
2015-02-28

文章信息/Info

Title:
Analysis of factors related to postoperative recurrence of benign meningiomas
文章编号:
1009-153X（2015）02-0090-03
作者:
祝　斐　颉　奎　饶　敏　黄　新　吴　明　金卫星　朱炯明
332000 江西九江，解放军171医院神经外科（祝　斐、颉　奎、黄　新、吴　明、金卫星、朱炯明）；332005 江西九江，九江学院医学院预防医学系（饶　敏）
通讯作者：颉　奎，E-mail：583677607@qq.com
Author(s):
ZHU Fei1;  XIE Kui1;  RAO Min2;  HUANG Xin1;  WU Ming1;  JIN Wei-xing1;  ZHU Jiong-ming1.
1. Department of Neurosurgery, The 171st Hospital, PLA, Jiujiang 332000, China;
2. Department of Preventive Medicine, Medical School, Jiujiang University, 332005 Jiujiang, China
关键词:
良性脑膜瘤; 显微手术; 复发; 影响因素
Keywords:
Meningioma; Lincical factors; postoperative recurrence
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2015.02.008
文献标志码:
A
摘要:
目的 探讨颅内良性脑膜瘤术后复发的影响因素。方法 回顾性总结分析从1988年1l月至2009年11月收治的178例单发良性脑膜瘤患者的临床资料。结果 178例患者术后随访5年，28例复发，复发率为15.7% 。单因素分析发现手术切除程度和肿瘤部位、形状、大小、边界、瘤周水肿、组织病理学类型及性别对脑膜瘤术后复发均有显著影响（P<0.05）；多因素logistic回归分析发现肿瘤部位、形状、边界、瘤周水肿、组织病理类型及手术切除程度可作为预测脑膜瘤复发的因素（>P<0.05）。>结论 影响良性脑膜瘤术后复发的影响因素很多。预防肿瘤复发的关键是手术切除要彻底，争取行Simpson 0级或者Ⅰ级切除；对于受累的硬脑膜、颅骨最好尽量切除；对于未能行Ⅰ级切除的患者，术后辅助放疗可以有效减缓肿瘤生长。
Abstract:
Objective To explore the factors related to the recurrence of benign intracranial meningiomas after the surgery. Methods The clinical data of 178 patients with benign intracranial meningiomas undergoing surgery from November, 1988 to November, 2009 in our hospital were analyzed retrospectively, including the operative, imaging and following up data. The univariate analysis and multivariate analysis were performed for understanding the factors related to the postoperative recurrence of the meningiomas. Results Of 178 patients with intracranial mengingiomas undergoing the surgery, 28 (15.7%) suffered from the tumor recurrence 5 years after the surgery and 150 not. The univariate analysis showed that the factors related to the mengingiomas recurrence included the extent of surgical resection, tumorous site, shape, size, border and histopathologic type, and the patients’ gender (P<0.05). multiariable="" logistic="" regression="" analysis="" showed="" that="" factors="" predicting="" the="" tumorous="" recurrence="" included="" site,="" shape,="" boundary="" and="" histopathologic="" type="" extent="" of="" surgical="" resection="" tumor.="">Conclusions It is suggested that the recurrence of ntracranial meningiomas may be related to the extent of surgical resection, tumorous site, shape, size, border and histopathologic type, peritomorous edema and gender, especially to the extent of the resection of the tumor and the tumorous histopathologic type.

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更新日期/Last Update: 2015-02-28