[1]王申浩　侯立军.去骨瓣减压术治疗老年恶性大脑中动脉梗死的疗效观察[J].中国临床神经外科杂志,2018,(02):93-95.
　WANG Shen-hao,HOU Li-jun..Effect of decompressive craniectomy on malignant middle cerebral artery infarction in old patients[J].,2018,(02):93-95.
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去骨瓣减压术治疗老年恶性大脑中动脉梗死的疗效观察 ()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年02期
页码:
93-95
栏目:
论著
出版日期:
2018-03-05

文章信息/Info

Title:
Effect of decompressive craniectomy on malignant middle cerebral artery infarction in old patients
文章编号:
1009-153X（2018）02-0093-03
作者:
王申浩　侯立军
作者单位：200003 上海，上海第二军医大学长征医院神经外科（王申浩、侯立军）
Author(s):
WANG Shen-hao;  HOU Li-jun.
Department of Neurosurgery, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China
关键词:
恶性大脑中动脉梗死; 老年; 去骨瓣减压术; 疗效
Keywords:
Malignant infarction;  Middle cerebral artery;  Decompressive craniectomy;  Old patients;  Prognosis
分类号:
R 743; R 651.1+1
文献标志码:
A
摘要:
目的 探讨去骨板减压术治疗老年（>60岁）恶性大脑中动脉梗死（MMI）的临床疗效。方法 回顾分析2011年8月至2016年8月收治的47例老年MMI的临床资料；其中21行去骨板减压术治疗（观察组），26例保守治疗（对照组）。发病12个月采用改良Rankin量表（mRS）评分和GOS评分评估预后，采用Log-rank χ2检验进行生存分析。结果 观察组发病3个月、半年和1年累积生存率（分别为71.75%、53.82%和35.88%）均明显高于对照组（分别为50.47%、33.65%和8.97%；P<0.05）。发病12个月，观察组mRS评分、GOS评分均明显优于对照组（P<0.05）。治疗后，观察组脑疝发生率（14.29%，3/21）明显低于对照组（57.69%，15/26；P<0.05）。结论 老年MMI行去骨瓣减压术较保守治疗可以提高生存率，并改善预后。
Abstract:
Objective To explore whether decompressive craniectomy can improve prognoses in old patients with malignant middle cerebral artery infarction (MMCAI). Methods The clinical data of 47 old patients with MMCAI, of whom, 21 underwent decompressive craniectomy and 26 were conservatively treated from August, 2011 to August, 2016, were analyzed retrospectively. GOS and modified Rankin Scale (mRS) were used to evaluate the prognoses in all the patients 12 months after the treatment. Results The survival rate (74.4%, 15/21) was significantly higher in the decompressive craniectomy group than that (34.6%, 9/26) in the conservative treatment group (P<0.05). The GOS scores and mRS scores were significantly better in the decompressive craniectomy group than those in the conservative treatment group (P<0.05). Conclusion The decompressive craniectomy can increase survival rate and improve the prognoses in the patients with MMCAI.

参考文献/References:

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更新日期/Last Update: 2018-03-05