[1]陈　虎　邓剑平　于　嘉　张　涛　刘宇峰　赵振伟.急性颅内大动脉粥样硬化性狭窄继发闭塞与单纯栓塞性闭塞的血管内治疗分析[J].中国临床神经外科杂志,2020,(02):70-72.[doi:10.13798/j.issn.1009-153X.2020.02.003]
　CHEN Hu,DENG Jian-ping,YU Jia,et al.Clinical characteristics of acute intracranial large artery atherosclerosis-related occlusion and effects of endovascular treatment: a comparison with intracranial artery thromboembolic occlusion[J].,2020,(02):70-72.[doi:10.13798/j.issn.1009-153X.2020.02.003]
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急性颅内大动脉粥样硬化性狭窄继发闭塞与单纯栓塞性闭塞的血管内治疗分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2020年02期
页码:
70-72
栏目:
论著
出版日期:
2020-02-25

文章信息/Info

Title:
Clinical characteristics of acute intracranial large artery atherosclerosis-related occlusion and effects of endovascular treatment: a comparison with intracranial artery thromboembolic occlusion
文章编号:
1009-153X（2020）02-0070-03
作者:
陈　虎　邓剑平　于　嘉　张　涛　刘宇峰　赵振伟
710038 西安，中国人民解放军空军军医大学唐都医院神经外科（陈　虎、邓剑平、于　嘉、张　涛、刘宇峰、赵振伟）
Author(s):
CHEN Hu;  DENG Jian-ping;  YU Jia;  ZHANG Tao;  LIU Yu-feng;  ZHAO Zhen-wei.
Department of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China
关键词:
颅内血管闭塞; 血管内治疗; 动脉粥样硬化; 血栓栓塞
Keywords:
Acute intracranial arteries occlusion;  Endovascular therapy;  Atherosclerosis;  Embolism
分类号:
R 743.3; R 815.2
DOI:
10.13798/j.issn.1009-153X.2020.02.003
文献标志码:
A
摘要:
目的 比较分析急性颅内大动脉粥样硬化性狭窄继发闭塞（CAS-O）与单纯栓塞性闭塞（EMB-O）的诊治特点。方法 回顾性分析2017年6月至2018年12月介入治疗的95例急性颅内大血管闭塞的临床资料，其中CAS-O 22例（23.2%），EMB-O 73例（76.8%）。结果 与EMB-O组比较，CAS-O组吸烟比例、后循环闭塞比例、球囊扩张比例、支架置入比例明显增高（P<0.05），合并心房纤颤及其他心脏疾病比例、前循环闭塞比例、血管成功再通率明显降低（P<0.05），手术操作时间明显延长（P<0.05）。两组术后脑实质出血发生率及术后3个月预后良好率均无统计学差异（P>0.05）。结论 与EMB-O比较，CAS-O吸烟比例较高，合并心房纤颤及其他心脏疾病比例低，后循环发生率高，手术时间长，再通率低，但术后脑实质出血发生率及术后3个月预后无明显差异。
Abstract:
Objective To explore the diagnosis and treatment of acute intracranial atherosclerosis-related occlusion (CAS-O) differing from the embolism-related occlusion (EMB-O). Methods The clinical data of 95 patients with acute intracranial arteries occlusion, of whom, 22 suffered from CAS-O and 73 from EMB-O, treated by endovascular therapy from June, 2017 to December, 2018 were analyzed retrospectively. The clinical characteristics and curative effects were analyzed and compared between the patients with CAS-O and the patients with EMB-O. Results The percentages of the smokers and the patients with posterior circulation artery occlusion were significantly higher, and percentage of the patients with atrial fibrillation and other cardic disease was significantly lower in the patients with CAS-O than those in the patients with EMB-O (P<0.05). The percentages of the patients of needing angioplasty with balloon and stent transplanataion were significantly higher in the patients with CAS-O than those in the patients with EMB-O (P<0.05). The operative duration was significantly longer, and rate of recanalization of occluded arteries was significantly lower in the patients with CAS-O than those in the patients with EMB-O (P<0.05). There were no significant differences in the incidence of cerebral hemorrhage and the rate of good prognosis 3 months after the treatment between both the groups (P>0.05). Conclusions Compared with EMB-O, CAS-O is more common in the smokers and occurs more often in the posterior circulation. EMB-O is more common in the patients with atrial fibrillation and other cardic diseases compared with CAS-O. The endovascular treatment of CAS-O often need angioplasty with the balloon and stent transplanatation and spends more time compared with treatment of EMB-O. The same effects of the endovascular treatment on CAS-O and EBM-O are observed 3 months after the treatment.

参考文献/References:

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备注/Memo

备注/Memo:
通讯作者：赵振伟，E-mail：zzwzc@sina.com（2019-08-11收稿，2019-11-04修回）
更新日期/Last Update: 2020-02-25