[1]邬　立　孙允伟　陆　斌　周子健　李方宝　李　洛.Rosa机器人辅助立体定向颅内活检术的临床应用[J].中国临床神经外科杂志,2021,26(08):584-586.[doi:10.13798/j.issn.1009-153X.2021.08.004]
　WU Li,SUN Yun-wei,LU Bin,et al.Clinical application of Rosa robot-assisted stereotactic intracranial biopsy[J].,2021,26(08):584-586.[doi:10.13798/j.issn.1009-153X.2021.08.004]
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Rosa机器人辅助立体定向颅内活检术的临床应用()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
26
期数:
2021年08期
页码:
584-586
栏目:
论著
出版日期:
2021-08-25

文章信息/Info

Title:
Clinical application of Rosa robot-assisted stereotactic intracranial biopsy
文章编号:
1009-153X（2021）08-0584-03
作者:
邬　立　孙允伟　陆　斌　周子健　李方宝　李　洛
Author(s):
WU Li;  SUN Yun-wei;  LU Bin;  ZHOU Zi-jian;  LI Fang-bao;  LI Luo.
Department of Neurosurgery, Eastern Branch, Qingdao Municipal Hospital, Qingdao 266000, China
关键词:
颅内病变; Rosa机器人; 立体定向活检术
Keywords:
Intracranial lsion;  Rosa robot;  Stereotactic biopsy
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2021.08.004
文献标志码:
A
摘要:
目的 探讨Rosa机器人辅助下立体定向颅内活检术的临床应用效果。方法 回顾性分析2018年10月至2020年8月在Rosa机器人辅助下进行颅内占位立体定向活检术的33例病人的临床资料。结果 术中没有发生导航故障，所有程序都如期完成。33例进行76个靶点穿刺活检术，术后未发现颅内出血，术后无癫痫发作。33例活检阳性率为100%，其中胶质瘤21例，弥漫大B细胞淋巴瘤5例，血管畸形2例，转移性腺瘤1例，生殖细胞肿瘤2例，间变性脑膜瘤1例，炎性脱髓鞘1例。21例胶质瘤中，检测出IDH-1突变6例（28.6%），MGMT启动子甲基化16例（76.2%）。1例间变性少突胶质细胞瘤检测出1p/19q杂合性缺失。结论 Rosa机器人辅助立体定向无框架活检术是一种相对安全，可行的操作，可用于颅内病变的组织学和分子诊断。
Abstract:
Objective To explore the efficacy of Rosa robot-assisted stereotactic intracranial biopsy. Methods The clinical data of 33 patients with intracranial lesion who underwent Rosa robot-assisted stereotactic intracranial biopsy from October 2018 from August 2020. Results There was no navigation failure during the operation, and all procedures were completed successfully. Seven-six biopses were performed on these 33 patients, with no intracranial hemorrhage and epileptic seizures after the operation. The positive rate was 100%, including 21 patients with glioma, 5 with diffuse large B-cell lymphoma, 2 with vascular malformation, 1 with metastatic adenoma, 2 with germ cell tumor, 1 with anaplastic meningioma, and 1 with inflammatory demyelination. Of 21 patients with glioma, IDH-1 mutation was detected in 6 patients (28.6%), and MGMT promoter methylation was detected in 16 patients (76.2%). The loss of 1p/19q heterozygosity was found in 1 patient with anaplastic oligodendroglioma. Conclusions Rosa robot-assisted stereotactic frameless biopsy is a relatively safe and feasible operation, which can be used for histological and molecular diagnosis of intracranial lesions.

参考文献/References:

[1] Chandrasoma PT, Smith MM, Apuzzo ML. Stereotacticbiopsy in the diagnosis of brain masses: comparison of results of biopsy and resected surgical specimen [J]. Neuro-surgery, 1989, 24(2): 160-165.
[2] Barnett GH, Miller DW, Weisenberger J. Frameless stereo-taxy with scalp-applied fiducial markers for brain biopsy procedures: experience in 218 cases [J]. J Neurosurg, 1999, 91(4): 569-576.
[3] Barnett GH, Kormos DW, Steiner CP, et al. Use of a frame-less, armless stereotactic wand for brain tumor localization with two-dimensional and three-dimensional neuroimaging [J]. Neurosurgery, 1993, 33(4): 674-678.
[4] Lefranc M, Capel C, Pruvot-Occean AS, et al. Frameless robotic stereotactic biopsies: a consecutive series of 100 cases [J]. J Neurosurg, 2015, 122(2): 342-352.
[5] Bekelis K, Radwan TA, Desai A, et al. Frameless roboticallytargeted stereotactic brain biopsy: feasibility, diagnostic yield, and safety [J]. J Neurosurg, 2012, 116(5): 1002-1006.
[6] Terrier L, Gilard V, Marguet F, et al. Stereotactic brain bio-psy: evaluation of robot-assisted procedure in 60 patients [J]. Acta Neurochir (Wien), 2019, 161(3): 545-552.
[7] Dawes W, Marcus HJ, Tisdall M, et al. Robot-assisted stereotactic brainstem biopsy in children: prospective cohortstudy [J]. J Robot Surg, 2019, 13(4): 575-579.
[8] Sciortino T, Fernandes B, Conti Nibali M, et al. Frameless stereotactic biopsy for precision neurosurgery: diagnostic value, safety, and accuracy [J]. Acta Neurochir (Wien), 2019, 161(5): 967-974.
[9] Savas A, Kanpolat Y. Safety and efficacy of frameless and frame-based intracranial biopsy techniques [J]. Acta Neurochir (Wien), 2008, 150(7): 737.
[10] Gaudin PB, Sherman ME, Brat DJ, et al. Accuracy of gradinggliomas on CT-guided stereotactic biopsies: a survival analysis [J]. Diagn Cytopathol, 1997, 17(6): 461-466.
[11] Zoeller GK, Benveniste RJ, Landy H, et al. Outcomes and management strategies after nondiagnostic stereotactic biopsies of brain lesions [J]. Stereotact Funct Neurosurg, 2009, 87(3): 174-181.
[12] Woodworth GF, McGirt MJ, Samdani A, et al. Frameless image-guided stereotactic brain biopsy procedure: diagno-stic yield, surgical morbidity, and comparison with the frame-based technique [J]. J Neurosurg, 2006, 104(2): 233-237.
[13] Meyer M, Reimand J, Lan X, et al. Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity [J]. Proc Natl Acad Sci USA, 2015, 112(3): 851-856.
[14] Dammers R, Schouten JW, Haitsma IK, et al. Towards improving the safety and diagnostic yield of stereotactic biopsy in a single centre [J]. Acta Neurochir (Wien), 2010, 152(11): 1915-1921.
[15] Barnett GH, Miller DW, Weisenberger J. Frameless stereo-taxy with scalp-applied fiducial markers for brain biopsy procedures: experience in 218 cases [J]. J Neurosurg, 1999, 91(4): 569-576.
[16] Gulsen S. Achieving higher diagnostic results in stereotacticbrain biopsy by simple and novel technique [J]. Open Access Maced J Med Sci, 2015, 3(1): 99-104.

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备注/Memo

备注/Memo:
作者单位：266000 山东青岛，青岛大学附属青岛市市立医院东院神经外科（邬　立、孙允伟、陆　斌、周子健、李方宝、李　洛）
通讯作者：李　洛，E-mail：liluo39@sina.com
更新日期/Last Update: 1900-01-01