[1]姜世豪,李映婷,买买提力·艾沙,等.儿童颅内动脉瘤的临床特点与治疗分析[J].中国临床神经外科杂志,2023,28(06):353-357.[doi:10.13798/j.issn.1009-153X.2023.06.001]
 JIANG Shi-hao,LI Ying-ting,MAIMAITILI Aisha,et al.Clinical characteristics and treatment of intracranial aneurysms in children[J].,2023,28(06):353-357.[doi:10.13798/j.issn.1009-153X.2023.06.001]
点击复制

儿童颅内动脉瘤的临床特点与治疗分析()
分享到:

《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
28
期数:
2023年06期
页码:
353-357
栏目:
论著
出版日期:
2023-06-30

文章信息/Info

Title:
Clinical characteristics and treatment of intracranial aneurysms in children
文章编号:
1009-153X(2023)06-0353-05
作者:
姜世豪李映婷买买提力·艾沙麦麦提亚生·麦麦提吐尔逊艾孜买提江·吐尔逊苏日青卡合尔曼·卡德尔成晓江
830054乌鲁木齐,新疆医科大学第一附属医院神经外科中心(姜世豪、买买提力·艾沙、麦麦提亚生·麦麦提吐尔逊、艾孜买提江·吐尔逊、苏日青、卡合尔曼·卡德尔、成晓江),介入治疗中心(李映婷)
Author(s):
JIANG Shi-hao1 LI Ying-ting2 MAIMAITILI Aisha1 MAIMAITIYASHENG Maimaitituerxun1 AIZIMAITIJIANG Tuerxun1 SU Ri-qing1 KAHEERMAN Kadeer1 CHENG Xiao-jiang1
1. Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China; 2. Interventional Therapy Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
关键词:
颅内动脉瘤小儿动脉瘤夹闭术血管内治疗临床特征疗效
Keywords:
Intracranial aneurysms Children Aneurysmal clipping Endovascular therapy Clinical features Clinical efficacy
分类号:
A
DOI:
10.13798/j.issn.1009-153X.2023.06.001
文献标志码:
R 749.3; R 651.1+2
摘要:
目的 探讨儿童颅内动脉瘤的临床特点、治疗方法及其疗效。方法 回顾性分析2012年1月至 2023年1月收治的33例小儿颅内动脉瘤的临床资料。结果 年龄6~17岁,平均(13.7±15.1)岁。33例共35枚动脉瘤,其中前循环26枚,后循环9枚;26例呈急性发病,合并蛛网膜下腔出血17例、脑内血肿8例、血肿破入脑室3例、脑积水1例。12例采取动脉瘤夹闭术,术后6个月mRS评分0~1分10例,2分1例,3分1例。7例选择血管内治疗,术后6个月mRS评分0~1分。3例巨大、夹层动脉瘤行颅外-颅内动脉分流术,术后6个月mRS评分0、1、2分各1例。10例选择保守治疗,6个月随访期内未新发卒中事件。1例放弃治疗,自动出院1周后死亡。结论 儿童颅内动脉瘤以男性多见,后循环动脉瘤占比高,临床症状多样;治疗上,建议首选动脉瘤夹闭术,对后循环动脉瘤及巨大、夹层动脉瘤,则可以选择血管内治疗或颅外-颅内动脉分流术。
Abstract:
Objective To investigate the clinical features, and treatment methods and outcomes of intracranial aneurysms in children. Methods The clinical data of 33 children with intracranial aneurysms who were admitted to our hospital from January 2012 to January 2023 were retrospectively analyzed. Results The average age was (13.7±15.1) years, ranging from 6 to 17 years. There were 35 aneurysms in 33 patients, including 26 aneurysms in anterior circulation and 9 aneurysms in posterior circulation. Of 26 patients with acute onset, 17 had subarachnoid hemorrhage, 8 intracerebral hematoma, 3 hematoma braking into the ventricle, and 1 hydrocephalus. A mRS score of 0~1 was achieved in 10 children and a score of 2~3 in 2 children of 12 children receiving aneurysmal clipping at 6 months after surgery. A mRS score of 0~1 was achieved in 7 children receiving endovascular treatment at 6 months after operation. A mRS score of 0, 1, and 2 was achieved in 3 childred with large or dissected aneurysms receiveing extra-intra cranial bypass at 6 months after operation, respectively. No new stroke occurred in 10 patients recieving conservative treatment during the 6-month follow-up. One case gave up treatment and died 1 week after discharge. Conclusions Pediatric intracranial aneurysms are more common in male children, with a higher proportion of posterior circulation aneurysms and diverse clinical symptoms. Aneurysmal clipping is recommended as the first choice, and endovascular treatment or extra-intra cranial bypass can be selected for posterior circulation aneurysms,giant aneurysms or dissecting aneurysms.

参考文献/References:

[1]Hetts SW, Narvid J, Sanai N, et al. Intracranial aneurysms in childhood: 27-year single-institution experience [J]. AJNR Am J Neuroradiol, 2009, 30(7): 1315-1324.
[2]Jian BJ, Hetts SW, Lawton MT, et al. Pediatric intracranial aneurysms [J]. Neurosurg Clin N Am, 2010, 21(3): 491-501.
[3]Rubin JM, Mirfakhraee M, Duda EE, et al. Intraoperative ultrasound examination of the brain [J]. Radiology, 1980, 137(3): 831-832.
[4]Afschrift M, Jeannin P, de Praeter C, et al. Ventricular taps in the neonate under ultrasonic guidance: technical note [J]. J Neurosurg, 1983, 59(6): 1100-1101.
[5]van Velthoven V, Auer LM. Practical application of intra-operative ultrasound imaging [J]. Acta Neurochir (Wien), 1990, 105(1-2): 5-13.
[6]李爱冰,李 俊,秦尚振,等. 儿童颅内动脉瘤的诊断和治疗[J]. 中国临床神经外科杂志,2006,11(9):519-520,523.
[7]Gew J, Sokol D, Gallo P, et al. De novo distal middle cerebral artery aneurysm post-excision of intracerebral arteriovenous malformation in an 8-year old [J]. Childs Nerv Syst, 2019, 35(11): 2211-2218.
[8]Garg K, Singh PK, Sharma BS, et al. Pediatric intracranial aneurysms--our experience and review of literature [J]. Childs Nerv Syst, 2014, 30(5): 873-883.
[9]Fulkerson DH, Voorhies JM, McCanna SP, et al. Endovas-cular treatment and radiographic follow-up of proximal traumatic intracranial aneurysms in adolescents: case series and review of the literature [J]. Childs Nerv Syst, 2010, 26(5): 613-620.
[10]Koroknay-Pál P, Lehto H, Niemel M, et al. Long-term out-come of 114 children with cerebral aneurysms [J]. J Neurosurg Pediatr, 2012, 9(6): 636-645.
[11]Gross BA, Smith ER, Scott RM, et al. Intracranial aneurysms in the youngest patients: characteristics and treatment challenges [J]. Pediatr Neurosurg, 2015, 50(1): 18-25.
[12]Lasjaunias P, Wuppalapati S, Alvarez H, et al. Intracranial aneurysms in children aged under 15 years: review of 59 consecutive children with 75 aneurysms [J]. Childs Nerv Syst, 2005, 21(6): 437-450.
[13]冯 欣,康慧斌,刘爱华,等. 儿童颅内动脉瘤的临床特点及治疗进展[J]. 中华神经医学杂志,2016,15(10):1067-1070.
[14]Koroknay-Pál P, Niemel M, Lehto H, et al. De novo and recurrent aneurysms in pediatric patients with cerebral aneurysms [J]. Stroke, 2013, 44(5): 1436-1439.
[15]Gemmete JJ, Toma AK, Davagnanam I, et al. Pediatric cerebral aneurysms [J]. Neuroimaging Clin N Am, 2013, 23(4): 771-779.
[16]梁建涛,凌 锋,鲍遇海. 儿童颅内动脉瘤的诊断治疗进展[J]. 中国脑血管病杂志,2008,5(10):477-479.
[17]Chen R, Zhang S, Xiao A, et al. Risk factors for intracranial aneurysm rupture in pediatric patients [J]. Acta Neurochir (Wien), 2022, 164(4): 1145-1152.
[18]Ciurea AV, Mohan A, Voicu A, et al. Characteristics and surgical outcomes of pediatric intracranial aneurysms in Romania [J]. Turk Neurosurg, 2021, 31(5): 740-744.
[19]Tawk RG, Hasan TF, D’Souza CE, et al. Diagnosis and treatment of unruptured intracranial aneurysms and aneurysmal subarachnoid hemorrhage [J]. Mayo Clin Proc, 2021, 96(7): 1970-2000.
[20]Guo X, Fang J, Wu Y. Risk factors of intracranial infection in patients after intracranial aneurysm surgery: implication for treatment strategies [J]. Medicine (Baltimore), 2021, 100(48): e27946.
[21]康慧斌,纪文军,钱增辉,等. 儿童颅内动脉瘤的临床特点和血管内治疗[J]. 中华神经外科杂志,2015,31(6):544-547.
[22]Asaithambi G, Adil MM, Shah KM, et al. Patterns of treatment and associated short-term outcomes of unruptured intracranial aneurysms in children [J]. Childs Nerv Syst, 2014, 30(10): 1697-1700.
[23]Shah VS, Martinez-Perez R, Kreatsoulas D, et al. Anatomic feasibility of endoscopic endonasal intracranial aneurysm clipping: a systematic review of anatomical studies [J]. Neurosurg Rev, 2021, 44(5): 2381-2389.
[24]刘福德,邓剑平,张 涛,等. 椎-基底动脉夹层动脉瘤的血管内治疗(附48例分析)[J]. 中国临床神经外科杂志,2016,21(6):353-356.

相似文献/References:

[1]曾 春 张施远 蒋永明.复合手术与常规夹闭术治疗颈内动脉后交通动脉破裂动脉瘤的疗效对比研究[J].中国临床神经外科杂志,2016,(05):257.[doi:10.13798/j.issn.1009-153X.2016.05.001]
 ZENG Chun,ZHANG Shi-yuan,JIANG Yong-ming.Analysis of the effects of hybrid surgery on posterior communicating artery aneurysms: a comparison with conventional craniotomy[J].,2016,(06):257.[doi:10.13798/j.issn.1009-153X.2016.05.001]
[2]周有东 敖祥生 刘汉东 王志勇 朱耀祖 周达全.支架辅助弹簧圈和单纯弹簧圈栓塞治疗颅内动脉瘤疗效及安全性的Meta分析[J].中国临床神经外科杂志,2016,(05):274.[doi:10.13798/j.issn.1009-153X.2016.05.006]
 ZHOU You-dong,AO Xiang-sheng,LIU Han-dong,et al.A mata-analysis of curative effects of stent-assisted coiling and simple coiling on intracranial aneurysms and their safety[J].,2016,(06):274.[doi:10.13798/j.issn.1009-153X.2016.05.006]
[3]赵 平 王雄伟 汪 雷 马金阳.显微手术和血管内栓塞术治疗颅内动脉瘤的疗效分析[J].中国临床神经外科杂志,2016,(05):281.[doi:10.13798/j.issn.1009-153X.2016.05.008]
 ZHAO Ping,WANG Xiong-wei,WANG Lei,et al.Effect of endovascular treatment on intracranial aneurysms: a comparison with microsurgery[J].,2016,(06):281.[doi:10.13798/j.issn.1009-153X.2016.05.008]
[4]李朝晖 王玉贵 张孟超 综述 赵兴利 审校.CT灌注成像在动脉瘤性蛛网膜下腔出血中的 临床应用进展[J].中国临床神经外科杂志,2016,(05):313.[doi:10.13798/j.issn.1009-153X.2016.05.021]
[5]刘福德 邓剑平 张 涛 陈 虎 李 帅 王俭博 曲友直 赵振伟.椎-基底动脉夹层动脉瘤的血管内治疗(附48例分析)[J].中国临床神经外科杂志,2016,(06):353.[doi:10.13798/j.issn.1009-153X.2016.06.011]
 LIU Fu-de,DENG Jian-ping,ZHANG Tao,et al.Endovascular treatment of vertebrobasilar artery dissecting aneurysms (report of 48 cases)[J].,2016,(06):353.[doi:10.13798/j.issn.1009-153X.2016.06.011]
[6]吴有志 罗良生 张 健 陈 骅 吴 鸣 刘 振 史 岩.前循环破裂动脉瘤伴脑内血肿的 早期显微手术治疗[J].中国临床神经外科杂志,2016,(06):376.[doi:10.13798/j.issn.1009-153X.2016.06.020]
[7]潘 力 刘 鹏 秦 杰 杨 柳 安学峰 吴 虓 杨 铭 徐国政 马廉亭.Y型支架辅助技术在颅内动脉分叉部宽颈动脉瘤治疗中的应用[J].中国临床神经外科杂志,2016,(07):394.[doi:10.13798/j.issn.1009-153X.2016.07.002]
 PAN Li,LIU Peng,QIN Jie,et al.Application of Y -configuration stent technique to treatment of intracranial wide-neck bifurcation aneurysms[J].,2016,(06):394.[doi:10.13798/j.issn.1009-153X.2016.07.002]
[8]周 量 刘 丛 张昌伟.早期栓塞术治疗动脉瘤性蛛网膜下腔出血的疗效[J].中国临床神经外科杂志,2016,(07):410.[doi:10.13798/j.issn.1009-153X.2016.07.007]
 ZHOU Liang,LIU Cong,ZHANG Chang-wei..Curative effect of early endovascular embolization on patients with ruptured intracranial aneurysms[J].,2016,(06):410.[doi:10.13798/j.issn.1009-153X.2016.07.007]
[9]张 莹 荆林凯 张倩倩 刘 健 张义森 王 坤 穆士卿 杨新健.颈内动脉后交通动脉小动脉瘤破裂危险因素分析[J].中国临床神经外科杂志,2016,(03):138.[doi:10.13798/j.issn.1009-153X.2016.03.002]
 ZHANG Ying,JING Lin-kai,ZHANG Qian-qian,et al.Analysis of risk factors related to rupture of small (diameter ≤5 mm) posterior communicating artery aneurysms[J].,2016,(06):138.[doi:10.13798/j.issn.1009-153X.2016.03.002]
[10]朱作磊 综述 罗良生 审校.动脉瘤性蛛网膜下腔出血的预后相关因素研究进展[J].中国临床神经外科杂志,2016,(03):183.[doi:10.13798/j.issn.1009-153X.2016.03.020]

备注/Memo

备注/Memo:
(2023-03-21收稿,2023-05-24修回)
基金项目:省部共建中亚高发病成因与防治国家重点实验室开放课题(SKL-HIDCA-2022-NKX4)
通讯作者:成晓江,E-mail:cxj711122@126.com
更新日期/Last Update: 2022-06-30