[1]王浩然,曲彦明,张宏伟,等.桥脑小脑角区脂肪瘤的诊治分析[J].中国临床神经外科杂志,2024,29(06):337-340346.[doi:10.13798/j.issn.1009-153X.2024.06.004]
　WANG Hao-ran,QU Yan-ming,ZHANG Hong-wei,et al.Diagnosis and treatment of patients with cerebellopontine angle lipoma[J].,2024,29(06):337-340346.[doi:10.13798/j.issn.1009-153X.2024.06.004]
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桥脑小脑角区脂肪瘤的诊治分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
29
期数:
2024年06期
页码:
337-340346
栏目:
论著
出版日期:
2024-06-30

文章信息/Info

Title:
Diagnosis and treatment of patients with cerebellopontine angle lipoma
文章编号:
1009-153X（2024）06-0337-04
作者:
王浩然; 曲彦明; 张宏伟; 谷春雨; 张明山
100093北京，首都医科大学三博脑科医院神经外科（王浩然、曲彦明、张宏伟、谷春雨、张明山）
Author(s):
WANG Hao-ran;  QU Yan-ming;  ZHANG Hong-wei;  GU Chun-yu;  ZHANG Ming-shan
Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
关键词:
颅脑肿瘤; 桥脑小脑角区; 脂肪瘤; 显微手术
Keywords:
Intracranial tumor;  Cerebellopontine angle;  Lipoma;  Microsurgery
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2024.06.004
文献标志码:
A
摘要:
目的 探讨桥脑小脑角区脂肪瘤的临床特点、治疗方法及其疗效。方法 回顾性分析2009年1月至2022年1月收治的6例桥脑小脑角区脂肪瘤的临床资料。结果 6例均出现患侧听力减退，伴眩晕、面神经功能障碍及面部疼痛各1例；MRI呈特异性短T1、长T2信号，CT呈低密度。4例手术治疗，2例保守观察。术后除听力下降以外的症状均得到缓解。出院后随访10~151个月，未出现疾病进展。结论 桥脑小脑角区脂肪瘤是先天性良性病变，影像表现较为特异；如出现明显临床症状，则可手术治疗，但手术难以保留残存听力，术中实现减压即可，不宜追求肿瘤切除程度。
Abstract:
Objective To explore the clinical features, treatment methods, and outcomes of patients with cerebellopontine angle (CPA) lipoma. Methods The clinical data of 6 patients with CPA lipoma treated at our hospital from January 2009 to January 2022 were retrospectively analyzed. Results All 6 patients presented with unilateral hearing loss, with vertigo, facial nerve dysfunction, and facial pain in 1 patient, respectively. MRI showed characteristic short T1 and long T2 signals, and CT showed low density in all 6 patients. Four patients underwent surgery, and 2 were observed conservatively. After surgery, all symptoms improved except hearing loss. The patients were followed up for 10~151 months after discharge, without any progression of the disease. Conclusions CPA lipoma is a congenital benign lesion with characteristic imaging findings. If obvious clinical symptoms occur, surgery can be performed, but it is difficult to preserve residual hearing. Reducing intracranial pressure during surgery is sufficient, and it is not advisable to pursue tumor resection to a high degree.

参考文献/References:

[1]TOTTEN DJ, MANZOOR NF, PERKINS EL, et al. Cerebellopontine angle and internal auditory canal lipomas: case series and systematic review[J]. Laryngoscope, 2021, 131(9): 2081-2087.
[2]CHIARAMONTE C, RABASTE S, JACQUESSON T, et al. Liponeurocytoma of the cerebellopontine angle[J]. World Neurosurg, 2018,112: 18-24.
[3]DONATI F, VASSELLA F, KAISER G, et al. Intracranial lipomas [J]. Neuropediatrics, 1992, 23(1): 32.
[4]KLEPAC N, HAJNSEK S, TOPIC I, et al. Radiology quiz case 1:lipoma of the CPA[J]. Arch Otolaryngol Head Neck Surg, 2009, 135: 828.
[5]LAGMAN C, VOTH BL, CHUNG LK. Evaluating the utility of a scoring system for lipomas of the cerebellopontine angle[J]. Acta Neurochir (Wien), 2017, 159: 739-750.
[6]FIGUEIREDO RR, DE AZEVEDO AA, FIGUEIREDO JA, et al. Cerebellopontine angle lipoma in asymptomatic patients: case report[J]. Otorhinolaryngol, 2016, 82: 741-742.
[7]GOMBERT M, MAILLEUX P. Cerebellopontine angle lipoma associated to dysplastic labyrinth[J]. J Belg Soc Radiol, 2018, 102(1): 43. [8]BERTOT B, STEELE WJ, BOGHANI Z, et al. Diagnostic dilemma: cerebellopontine angle lipoma versus dermoid cyst[J]. Cureus, 2017, 9(11): e1894.
[9]JABOT G, STOGUART-ELSANKARY S, SALIOU G, et al. Intracranial lipomas: clinical appearances on neuroimaging and clinical significance[J]. J Neurol, 2009, 256(6): 851-855.
[10]L EM ARC'HADOUR F, MOURET P, BO ST F, et al. Lipoma of the internal auditory canal. An anatomoclinical case study and review of the literature about cranial nerve lipomas[J]. Arch Anat Cytol Pathol, 1991, 39(4): 147-150.
[11]IPLIKCIOGLU C, BIKMAK K, GOKDUMAN CA, et al. Cerebellopontine angle lipoma with extracranial extension[J]. J Clin Neurosci,2006, 13(10): 1045-1047.
[12]VERNOOIJ MW, IKRSM MA, VINCENT AJ, et al. Intravestibular lipoma: an important imaging diagnosis[J]. Arch Otolaryngol Head Neck Surg, 2008, 134(11): 1225-1228.
[13]BACCIU A, DI LELLA F, VENTURA E, et al. Lipomas of the internal auditory canal and cerebellopontine angle[J]. Ann Otol Rhinol Laryngol, 2014, 123: 58-64.
[14]KONTORINIS G, FREEMAN SR, POTTER G. Management of cerebellopontine angle lipomas: need for long-term radiologic surveillance[J]. Otol Neurotol, 2014, 35: 163-168.
[15]KIM KH, LEE YH, PARK YS, et al. Rapidly regrowing lipoma inlipomeningomyelocele: a case report[J]. Childs Nerv Syst, 2009, 25(9): 1149-1151.

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备注/Memo

备注/Memo:
（2022-05-30收稿，2024-08-20修回）
更新日期/Last Update: 2024-06-30