[1]王洪流 陈谦学 田道锋 张申起 刘宝辉 彭泽生.巨大垂体腺瘤分期手术治疗分析[J].中国临床神经外科杂志,2015,(08):453-455.[doi:10.13798/j.issn.1009-153X.2015.08.002]
 WANG Hong-liu,CHEN Qian-xue,TIAN Dao-feng,et al.Surgical treatment of giant pituitary adenomas by stages (report of 11 cases)[J].,2015,(08):453-455.[doi:10.13798/j.issn.1009-153X.2015.08.002]
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巨大垂体腺瘤分期手术治疗分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年08期
页码:
453-455
栏目:
论著
出版日期:
2015-08-25

文章信息/Info

Title:
Surgical treatment of giant pituitary adenomas by stages (report of 11 cases)
文章编号:
1009-153X(2015)08-0453-03
作者:
王洪流 陈谦学 田道锋 张申起 刘宝辉 彭泽生
430060 武汉,武汉大学人民医院神经外科[王洪流(进修医生,现在湖北省荆州市第二人民医院工作)、陈谦学、田道锋、张申起、刘宝辉、彭泽生]
Author(s):
WANG Hong-liu CHEN Qian-xue TIAN Dao-feng ZHANG Shen-qi LIU Bao-hui PENG Ze-sheng.
Department of Neurosurgery, People’s Hospital, Wuhan University, Wuhan 430060, China
关键词:
巨大垂体腺瘤分期手术疗效
Keywords:
Giant pituitary adenomas Surgery by stage Treatment Curative effect
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2015.08.002
文献标志码:
A
摘要:
目的 探讨经额入路联合经鼻蝶入路分期手术切除巨大垂体腺瘤的方法及其疗效。方法 回顾性分析2011年6月至2014年6月分期手术切除11例巨大垂体腺瘤患者的临床资料,全部患者均采取Ⅰ期经额入路切除鞍上及脑室内肿瘤,Ⅱ期经鼻-蝶入路显微手术切除鞍内肿瘤。结果 肿瘤全切除9例,次全切除2例。术后均无颅内感染及严重的并发症,无死亡病例。术后随访2个月至3年,11例患者的临床症状均有明显改善;垂体激素水平恢复正常4例,较术前明显下降5例,轻度下降2例。结论 根据患者病史及影像学资料,分析肿瘤的生长形态及质地,选择分期手术治疗巨大垂体腺瘤,具有对脑组织损伤小、并发症少、全切率高等优点,是一种安全、有效的手术方式。
Abstract:
Objective To explore the technique of surgery by stages for the giant pituitary adenomas and its curative effect. Method The clinical data of 11 patients with pituitary macroadenomas who underwent the surgery by stages from Jun, 2011 to Jun, 2014, were analyzed retrospectively. The first stage surgery via the transsubfrontal approach for the suprasellar and intraventricular tumors was performed in all the patients, in whom the second stage surgery via nasal-transsphenoidal approach for the intrasellar tumors was performed. Results Of 11 patients, 9 received total resection of the tumors and 2 subtotal. Conclusions The morphology and texture of giant pituitary adenomas should be analyzed according to patient’s medical history and imaging data before the surgery by stages, which is a safe effective and minimally invasive method. The curative effect of the surgery by stage on the giant pituitary adenoma is good because it is of less injury to the cerebral tissues, few postoperative complications and high rate of the total resection of the tumors.

参考文献/References:

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备注/Memo

备注/Memo:
通讯作者:陈谦学,E-mail:chenqx666@sohu.com.cn
更新日期/Last Update: 2016-08-25