[1]张鹏飞 赵立文 汪子文 唐 铸 赵文可 何一川 杨俊丽 于耀宇.内膜斑块剥脱术与支架置入术治疗颈动脉狭窄的Meta分析[J].中国临床神经外科杂志,2016,(08):455-457.[doi:10.13798/j.issn.1009-153X.2016.08.003]
 ZHANG Peng-fei,ZHAO Li-wen,WANG Zi-wen,et al.Endarterectomy versus stenting for carotid artery stenosis: a meta-analysis of randomized controlled clinical trials[J].,2016,(08):455-457.[doi:10.13798/j.issn.1009-153X.2016.08.003]
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内膜斑块剥脱术与支架置入术治疗颈动脉狭窄的Meta分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2016年08期
页码:
455-457
栏目:
论著
出版日期:
2016-08-18

文章信息/Info

Title:
Endarterectomy versus stenting for carotid artery stenosis: a meta-analysis of randomized controlled clinical trials
文章编号:
1009-153X(2016)08-0455-04
作者:
张鹏飞 赵立文 汪子文 唐 铸 赵文可 何一川 杨俊丽 于耀宇
300162 天津,武警后勤学院附属医院神经外科(张鹏飞、赵立文、汪子文、唐 铸、赵文可、何一川、杨俊丽、于耀宇) 300162 辽宁锦州;锦州医科大学研究生院(张鹏飞、赵立文)
通讯作者:于耀宇,E-mail:yyuyaoyu666@aliyun.com
Author(s):
ZHANG Peng-fei12 ZHAO Li-wen12 WANG Zi-wen1 TANG Zhu1 ZHAO Wen-ke1 HE Yi-chuan1 YANG Jun-li1 YU Yao-yu1.
1. Department of Neurosurgery, The Affiliated Hospital, Logistics College, People’s Armed Police Force, Tianjin 300162, China;
2. Graduate school, Jinzhou Medical University, Jinzhou 121000, China
关键词:
颈动脉狭窄内膜剥脱术支架置入术Meta分析
Keywords:
Carotid stenosis Endarterectomy Carotid stenting Meta-analysis
分类号:
R 743.3; R 815.2
DOI:
10.13798/j.issn.1009-153X.2016.08.003
文献标志码:
A
摘要:
目的 探讨颈动脉内膜斑块剥脱术(CEA)与颈动脉支架置入术(CAS)治疗颈动脉狭窄的疗效。方法 计算机检索Pubmed、Embase数据库,收集CEA与CAS治疗颈动脉狭窄的随机对照研究,应用Stata软件进行统计分析。结果 共纳入12项研究,共7 401例患者。Meta分析结果显示:术后30 d,CAS组卒中和死亡联合事件发生率(OR=1.51,95% CI为1.23~1.84;P<0.001)、任意卒中事件发生率(or ci为1.18~1.83;P<0.001)均明显高于cea组;而心肌梗死发生率(or ci为0.28~0.75;p="0.002)、颅神经损伤发生率(OR=0.08,95%" ci为0.04~0.14;P<0.001)均明显低于cea组。两组致残性卒中和死亡联合事件发生率(or ci为0.93~1.77;p="0.13)、病死率(OR=1.52,95%" ci为0.96~2.41;p="0.07)、致残性卒中发生率(OR=1.16,95%" ci为0.79~1.71;p="0.46)无明显差异。<b">结论 CAS治疗颈动脉狭窄短期安全性和有效性与CEA类似。
Abstract:
Objective To evaluate the efficacy of carotid artery stenting (CAS) and carotid enadrterectomy (CEA) for carotid stenoses. Method The randomized clinical trials of CAS versus CEA for carotid stenoses were searched from the databases including Medline and Embase. The meta-analysis of the searched data was performed by Stata software. Results A total of 12 trials involving 7 401 patients were finally included. Meta-analysis showed that the occurent rates of stroke (OR=1.47, 95% CI 1.18 to 1.83, P<0.001) and="" stroke="" death="" (or="1.51," 95%="" ci="" 1.23="" to="" 1.84,="">P<0.001) 30="" days="" after="" the="" treatment="" were="" significantly="" higher="" in="" cas="" group="" than="" those="" cea="" group.="" occurent="" rates="" of="" myocardial="" infarctions="" (or="" 0.46,="" 95%="" ci="" 0.28="" to="" 0.75,="" p="0.002)" and="" cranial="" nerve="" injury="" 0.04="" 0.14,="">P

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更新日期/Last Update: 2016-08-19