[1]陈艳芳 王梦阳 翟 锋 栾国明 于思科 王 茜 周 健.前颞叶切除术对颞叶癫痫病人认知功能的影响[J].中国临床神经外科杂志,2017,(06):376-378.[doi:10.13798/j.issn.1009-153X.2017.06.003]
 CHEN Yan-fang,WANG Meng-yang,ZHAI Feng,et al.Effects of anterior temporal lobectomy on cognitive function in patients with temporal lobe epilepsy[J].,2017,(06):376-378.[doi:10.13798/j.issn.1009-153X.2017.06.003]
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前颞叶切除术对颞叶癫痫病人认知功能的影响 ()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年06期
页码:
376-378
栏目:
论著
出版日期:
2017-06-25

文章信息/Info

Title:
Effects of anterior temporal lobectomy on cognitive function in patients with temporal lobe epilepsy
文章编号:
1009-153X(2017)06-0376-03
作者:
陈艳芳 王梦阳 翟 锋 栾国明 于思科 王 茜 周 健
100093 北京,首都医科大学三博脑科医院神经心理室(陈艳芳),神经内科(王梦阳、王 茜),神经外科(翟 锋、栾国明、于思科、周 健)
通讯作者:周 健,E-mail:zhoujian5151@163.com
Author(s):
CHEN Yan-fang1 WANG Meng-yang1 ZHAI Feng2 LUAN Guoming2 YU Si-ke2 WANG Qian1 ZHOU Jian2.
1. Department of Neurology, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China;
2. Department of Neurosuegry, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China
关键词:
颞叶癫痫前颞叶切除术认知功能记忆力操作智商
Keywords:
Temporal lobe epilepsy Temporal lobectory Cognitive function Memory Performance Intelligence
分类号:
R 742.1; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2017.06.003
文献标志码:
A
摘要:
目的 分析不同侧别前颞叶切除手术对颞叶癫痫(TLE)病人认知功能的影响。方法 回顾性分析2014~2015年行标准单侧前颞叶及内侧结构切除的44例TLE的临床资料,分析术前及术后1年韦氏智力分测验即言语智商(VIQ)、操作智商(PIQ),以及术前、术后3个月、术后1年复查韦氏记忆量表(MQ)中的理解和再生分测验结果。结果 左侧手术TLE病人术后1年PIQ较术前显著提升(P<0.05),右侧手术TLE病人术后1年MQ较术前显著提升(P<0.05)。左侧手术TLE病人术后3个月理解分测验分数较术前明显下降(P<0.05),术后1年与术前无显著性差异(P>0.05);再生分测验分数术后3个月较术前无明显变化(P>0.05),术后1年较术前明显提升(P<0.05)。右侧手术TLE病人理解分数和再生分数手术前后均无显著差异(P>0.05)。结论 左侧颞叶手术主要改善TLE病人PIQ,而右侧颞叶手术则主要改善TLE病人记忆力。
Abstract:
Objective To investigate the effects of left or right anterior temporal lobectomy on cognitive function in patients with temporal lobe epilepsy (TLE). Methods The clinical data of 44 patients with TLE undergoing the resection of the unilateral anteriolateral temporal lobe and medial structures from 2014 to 2015 were analyzed retrospectively. The examination of Wechsler Verbal Intelligence Quotient (VIQ) and Operational Intelligence Quotient (PIQ) were performed in all the patients before and 1 year after the operation. The examinations of Wechsler Memory Quotient (MQ) including the understanding and regeneration tests were performed in all the patients 3 months and 1 year after the operation. Results The scores of PIQ were significantly higher 1 year after the operation than those before the operation in the patients with TLE undergoing left temporal lobectomy (P<0.05). The scores of MQ were significantly higher in the patients with TLE undergoing right temporal lobectomy (P<0.05). The scores of understanding test were lower 3 months after the operation than those before the operation in the patients with TLE under left temporal lobectomy (P<0.05), in whom the scores of regenerative test 3 months after the operation were insignificantly different from those before the operation (P>0.05). The scores of regenerative test were significantly higher 1 year after the operation than those before the operation in the patients undergoing left temporal lobectomy (P<0.05), in whom the scores of regenerative test 3 months after the operation were insignificantly different from those before the operation (P>0.05). The scores of the understanding and regenerative tests 3 months and 1 year after the operation were insignificantly different respectively from those before the operation in the patients with TLE undergoing the right temporal lobectomy (P>0.05). Conclusion The left temporal lobectomy can mainly improve PIQ, while the right temporal lobectomy can mainly improve MQ in patients with TLE.

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备注/Memo

备注/Memo:
基金项目:北京市科学技术委员会首都特色课题(Z131107002213012)
更新日期/Last Update: 2017-06-25