参考文献/References:
[1] Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013
[J]. CA Cancer J Clin, 2013, 63(1): 11-30.
[2] Reardon DA, Rich JN, Friedman HS, et al. Recent advances
in the treatment of malignant astrocytoma [J]. J Clin Oncol,
2006, 24(8): 1253-1265.
[3] Mittal S, Pradhan S, Srivastava T. Recent advances in tar-
geted therapy for glioblastoma [J]. Expert Rev Neurother,
2015, 15(8): 935-946.
[4] Babu R, Kranz PG, Agarwal V, et al. Malignant brainstem
gliomas in adults: clinicopathological characteristics and
prognostic factors [J]. J Neurooncol, 2014, 119(1): 177-185.
[5] Valinezhad OA, Safaralizadeh R, Kazemzadeh-Bavili M.
Mechanisms of miRNA-mediated gene regulation from
common downregulation to mRNA-specific upregulation
[J]. Int J Genomics, 2014, 2014: 970607.
[6] Bushati N, Cohen SM. MicroRNA functions [J]. Annu Rev
Cell Dev Biol, 2007, 23: 175-205.
[7] Hwang HW, Mendell JT. MicroRNAs in cell proliferation,
cell death, and tumorigenesis [J]. Br J Cancer, 2006, 94(6):
776-780.
[8] Calin GA, Croce CM. MicroRNA signatures in human can-
cers [J]. Nat Rev Cancer, 2006, 6(11): 857-866.
[9] Slack FJ, Weidhaas JB. MicroRNA in cancer prognosis [J].
N Engl J Med, 2008, 359(25): 2720-2722.
[10] Tivnan A, McDonald KL. Current progress for the use of
miRNAs in glioblastoma treatment [J]. Mol Neurobiol,
2013, 48(3): 757-768.
[11] Karsy M, Arslan E, Moy F. Current progress on understan-
ding microRNAs in glioblastoma multiforme [J]. Genes
Cancer, 2012, 3(1): 3-15.
[12] Galardi S, Mercatelli N, Giorda E, et al. miR-221 and miR-
222 expression affects the proliferation potential of human
prostate carcinoma cell lines by targeting p27Kip1 [J]. J
Biol Chem, 2007, 282(32): 23716-23724.
[13] Kneitz B, Krebs M, Kalogirou C, et al. Survival in patients
with high-risk prostate cancer is predicted by miR-221,
which regulates proliferation, apoptosis, and invasion of
prostate cancer cells by inhibiting IRF2 and SOCS3 [J].
Cancer Res, 2014, 74(9): 2591-2603.
[14] Falkenberg N, Anastasov N, Rappl K, et al. MiR-221/-222
differentiate prognostic groups in advanced breast cancers
and influence cell invasion [J]. Br J Cancer, 2013, 109(10):
2714-2723.
[15] Quintavalle C, Garofalo M, Zanca C, et al. miR-221/222
overexpession in human glioblastoma increases invasiveness
by targeting the protein phosphate PTPmu [J]. Oncogene,
2012, 31(7): 858-868.
[16] He H, Jazdzewski K, Li W, et al. The role of microRNA
genes in papillary thyroid carcinoma [J]. Proc Natl Acad Sci
USA, 2005, 102(52): 19075-19080.
[17] Qin B, Cao Y, Yang H, et al. MicroRNA-221/222 regulate
ox-LDL-induced endothelial apoptosis via Ets-1/p21
inhibition [J]. Mol Cell Biochem, 2015, 405(1-2): 115-124.
[18] Ciafre SA, Galardi S, Mangiola A, et al. Extensive modula-
tion of a set of microRNAs in primary glioblastoma [J]. Bio-
chem Biophys Res Commun, 2005, 334(4): 1351-1358.
[19] Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO
classification of tumours of the central nervous system [J].
Acta Neuropathol, 2007, 114(2): 97-109.
[20] Li B, Lu Y, Wang H, et al. miR-221/222 enhance the tu-
morigenicity of human breast cancer stem cells via modu-
lation of PTEN/Akt pathway [J]. Biomed Pharmacother,
2016, 79: 93-101.
[21] Shi J, Zhang Y, Jin N, et al. MicroRNA-221-3p plays an
oncogenic role in gastric carcinoma by inhibiting PTEN
expression [J]. Oncol Res, Epub, 2016.
[22] Cheedipudi S, Puri D, Saleh A, et al. A fine balance: epige-
netic control of cellular quiescence by the tumor suppressor
PRDM2/RIZ at a bivalent domain in the cyclin a gene [J].
Nucleic Acids Res, 2015, 43(13): 6236-6256.
[23] Tan SX, Hu RC, Liu JJ, et al. Methylation of PRDM2,
PRDM5 and PRDM16 genes in lung cancer cells [J]. Int J
Clin Exp Pathol, 2014, 7(5): 2305-2311.