[1]赵文可　张鹏飞　黄昌恒　姚自同　魏孟广　于耀宇.支架取栓技术与接触抽吸技术治疗急性颅内大血管闭塞的Meta分析[J].中国临床神经外科杂志,2018,(06):388-391.[doi:10.13798/j.issn.1009-153X.2018.06.002]
　ZHAO Wen-ke,ZHANG Peng-fei,HUANG Chang-heng,et al.Contact aspiration versus stent thrombectomy for large vessel ischemic strokes: a meta-analysis of randomized controlled trials[J].,2018,(06):388-391.[doi:10.13798/j.issn.1009-153X.2018.06.002]
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支架取栓技术与接触抽吸技术治疗急性颅内大血管闭塞的Meta分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年06期
页码:
388-391
栏目:
论著
出版日期:
2018-06-25

文章信息/Info

Title:
Contact aspiration versus stent thrombectomy for large vessel ischemic strokes: a meta-analysis of randomized controlled trials
文章编号:
1009-153X（2018）06-0388-04
作者:
赵文可　张鹏飞　黄昌恒　姚自同　魏孟广　于耀宇
作者单位：453000 河南新乡，新乡医学院神经外科（赵文可）；300162 天津，武警后勤学院附属医院神经外科（张鹏飞、黄昌恒、姚自同、于耀宇）；300162 天津，武警后勤学院附属医院神经外二科（魏孟广）
Author(s):
ZHAO Wen-ke1;  ZHANG Peng-fei2;  HUANG Chang-heng2;  YAO Zi-tong2;  WEI Meng-guang3;  YU Yao-yu2.
1. Department of Neurosurgery, Xinxiang Medical College, Xinxiang 453000, China; 2. Department of Neurosurgery, Affiliated Hospital, Logistics College, Armed Police Command, Tianjin 300162, China; 3. The Second Department of Neurosurgery, Affiliated Hospital, Logistics College, Armed Police Command, Tianjin 300162, China
关键词:
急性颅内大血管闭塞; 支架取栓术接触; 抽吸技术; 疗效; Meta分析
Keywords:
Ischemic stroke;  Contact aspiration;  Stent thrombectomy;  Large vessels;  Meta-analysis
分类号:
R 743; R 815.2
DOI:
10.13798/j.issn.1009-153X.2018.06.002
文献标志码:
A
摘要:
目的 系统评价接触抽吸技术与支架取栓技术治疗发病6 h内颅内大血管闭塞的有效性和安全性。方法 计算机检索Pubmed、Embase、ClinicalTrials.gov以及Cochrane数据库，收集支架取栓术与接触抽吸术治疗大血管闭塞的随机对照研究，应用Review Manager 5.3软件进行Meta分析。结果 共纳入9项研究，共2 851例病人。Meta分析结果显示：两组术后血管再灌注成功率（OR=1.17；95% CI：0.57~2.41；P=0.66）、术后24 h内脑出血发生率（OR=0.97；95% CI：0.68~1.39；P=0.89）、术后90 d预后良好率（OR=7.59；95% CI：1.94~29.72；P=0.82）均无统计学差异，但是支架取栓组病死率明显高于接触抽吸组（OR=7.59；95% CI：1.94~29.72；P=0.004）。结论 对于急性颅内大血管闭塞，接触抽吸技术在血管再灌注成功率、术后脑出血风险、预后良好率方面与支架取栓技术相近，但接触抽吸相比较支架取栓的病死率更低。
Abstract:
Objective To compare the effectiveness and safety of contact aspiration with those of stent thrombolysis within 6 hours after onset of stroke in patients with large vessel ischemic stroke. Methods The Pubmed, Embase, ClinicalTrials.gov and Cochrane databases were searched by computer for randomized controlled trials of stent thrombectomy and contact aspiration for the large vessel ischemic stroke. Meta analysis was performed with review manager 5.3 software. Results A total of 9 articles which were enrolled in this study included 2 851 patients. The results of Meta-analysis showed that there were no significant differences in the postoperative vascular reperfusion and the rate of adverse events between contact aspiration group and stent thrombectomy group. The rale of death was significantly higher in the stent thrombectomy group than that in the contact aspiration group (OR=7.59, 95% CI: 1.94~29.72, P=0.004). There was no significant difference in the rate of good prognosis between both the groups. Conclusion The contact aspiration technique is similar to the stent thrombectomy in the postoperative vascular reperfusion and adverse events, but the rate of death is significantly lower in the patients with large vessel ischemic stroke receiving contact aspiration than that in the patients with large vessel ischemic stroke receiving stent thrombectomy.

参考文献/References:

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备注/Memo

备注/Memo:
通讯作者：于耀宇，E-mail：yuyaoyu666@aliyun.com
更新日期/Last Update: 2018-06-25