[1]李志强　李筱姝　夏吉勇等.3D Slicer多模态影像融合技术在脑膜瘤手术中的应用[J].中国临床神经外科杂志,2021,26(10):758-760.[doi:10.13798/j.issn.1009-153X.2021.10.005]
　LI Zhi-qiang,LI Xiao-shu,XIA Ji-yong,et al.Application of 3D Slicer multimodal image fusion technique in surgery for patients with skull base meningioma or giant meningioma[J].,2021,26(10):758-760.[doi:10.13798/j.issn.1009-153X.2021.10.005]
点击复制

3D Slicer多模态影像融合技术在脑膜瘤手术中的应用()
分享到：

《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
26
期数:
2021年10期
页码:
758-760
栏目:
论著
出版日期:
2021-10-25

文章信息/Info

Title:
Application of 3D Slicer multimodal image fusion technique in surgery for patients with skull base meningioma or giant meningioma
文章编号:
1009-153X（2021）10-0758-03
作者:
李志强　李筱姝　夏吉勇等
作者单位：102300，北京市门头沟区医院神经外科（李志强、李筱姝、夏吉勇、徐　亮、孙跃春、苗　林、任雅盼）
Author(s):
LI Zhi-qiang;  LI Xiao-shu;  XIA Ji-yong;  et al
Department of Neurosurgery, Beijing Mentougou District Hospital, Beijing 102300, China
关键词:
颅底脑膜瘤; 巨大脑膜瘤; 显微手术; 3D Slicer软件; 多模态影像融合技术; 疗效
Keywords:
Skull base meningioma;  Giant meningioma;  3D Slicer multimodal image fusion technique;  Microsurgery
分类号:
A
DOI:
10.13798/j.issn.1009-153X.2021.10.005
文献标志码:
R 739.41; R 651.1+1
摘要:
目的 探讨3D Slicer多模态影像融合技术在颅底脑膜瘤或巨大脑膜瘤手术治疗中的应用效果。方法 回顾性分析2016年6月至2019年5月应用3D Slicer多模态影像融合技术辅助手术治疗的12例颅底脑膜瘤或巨大脑膜瘤的临床资料。术前完善头颅CT、MRI、TOF-MRA、DTI序列检查，将得到的DICOM格式的影像学数据，应用3D Slicer软件进行处理，对肿瘤、相邻颅骨、重要动脉、颅神经、静脉、静脉窦、锥体束进行多模态融合和三维重建，明确肿瘤与周围结构的关系，通过3D虚拟可视化图像，模拟手术入路，精准术前规划，辅助进行手术治疗。结果 12例中，肿瘤全切除10例（83.33%，10/12），次全切除2例。无手术死亡病例，无术区血肿及颅神经损伤。术后出现对侧肢体肌力下降或原有偏瘫症状加重2例，经治疗后肌力恢复正常。12例术后随访6个月，未见肿瘤复发或增大。结论 对于颅底脑膜瘤或巨大脑膜瘤的手术治疗，3D Slicer多模态影像融合技术可以帮助制定详尽的术前规划，减少手术并发症，提高肿瘤的全切除率。
Abstract:
Objective To explore the application value of 3D Slicer multimodal image fusion technique in the surgical treatment of patients with skull base meningioma or giant meningioma. Methods The clinical data of 12 patients with skull base meningioma or giant meningioma who underwent surgery assisted by 3D Slicer multi-modal image fusion technique from June 2016 to May 2019 were retrospectively analyzed. Examinations of head CT, MRI, TOF-MRA, DTI sequence were performed before the surgery, and 3D Slicer software was used to process the acquired imaging data in DICOM format to clarify the relationship between the tumor and the surrounding tissues inclusing adjacent skulls, important arteries, cranial nerves, veins, venous sinuses, and pyramidal tract. The surgical approach was simulated and the precise preoperative planning was made to assist the surgical treatment by the 3D virtual visualization image. Results Total tumor resection was achieved in 10 of 12 patients (83.33%, 10/12) and subtotal in 2. There were no operative deaths, and no hematomas and cranial nerve injuries in the operation region. After the operation, the contralateral limb muscle strength decreased or the original symptoms of hemiplegia were aggravated in 2 patients, and the muscle strength returned to normal after treatment. The follow up (6 months) reseults showed no tumor recurrence or enlargement. Conclusions For the surgical treatment of patients with skull base meningioma or giant meningioma, 3D Slicer multimodal image fusion technique can help to make detailed preoperative planning, reduce surgical complications, and increase the total tumor resection rate.

参考文献/References:

[1] Song F, Hou Y, Sun G, et al. In vivo visualization of the facial nerve in patients with acoustic neuroma using diffu-sion tensor imaging-based fiber tracking [J]. J Neurosurg, 2016, 125(4): 787-794.
[2] 杨学军，江　涛. 解读《世界卫生组织中枢神经系统肿瘤分类（2016年）》[J]. 中国神经精神疾病杂志，2016，42（6）：321-329.
[3] Huang X, Xu J, Xu M, et al. Functional outcome and com-plications after the microsurgical removal of giant vestibularschwannomas via the retrosigmoid approach: a retrospective review of 16-year experience in a single hospital [J]. BMC Neurol, 2017, 17(1): 18.
[4] 张越琦. 混合现实技术辅助神经外科精准手术研究进展[J]. 国际神经病学神经外科学杂志，2019，46（2）：217-222.
[5] Hou Z, Chen X, Shi XJ. Comparison of neuronavigation and frame-based stereotactic systems in implanting epileptic depth electrodes [J]. Turk Neurosurg, 2016, 26(4): 574-581.
[6] Blanc R, Seiler A, Robert T, et al. Multimodal angiographic asses sment of cerebral arteriovenous malformations: a pilot study [J]. J Neurointerv Surg, 2015, 7(11): 841-847.
[7] 谢国强，周小卫，左　毅，等. 基于智能手机的简易增强现实技术对幕上高血压性脑内血肿定位的价值[J]. 中国临床神经外科杂志，2019，24（6）：345-347，351.
[8] 孙国臣，陈晓雷，侯远征，等. 基于简易虚拟现实和增强现实定位的内镜辅助下清除幕上自发性脑内血肿[J]. 中华神经外科杂志，2017，33（1）：15-18.
[9] 姬　将，赵超云，王明磊，等. Slicer三维可视化后处理软件进行3D-CTA重建诊断颅内破裂动脉瘤的准确性[J]. 中国临床神经外科杂志，2019，24（8）：476-479.

相似文献/References:

[1]付　强　张玉定　高庆飞　程品文　王　雄.超选择性栓塞联合显微手术治疗巨大脑膜瘤[J].中国临床神经外科杂志,2016,(02):94.[doi:10.13798/j.issn.1009-153X.2016.02.012]
　FU Qiang,ZHANG Yu-ding,GAO Qiang-fei,et al.Microsurgery for giant meningiomas after preoperative super-selective embolization[J].,2016,(10):94.[doi:10.13798/j.issn.1009-153X.2016.02.012]
[2]应建有　谭占国　谭翱勇　袁　波.颅内巨大脑膜瘤的显微手术治疗[J].中国临床神经外科杂志,2015,(12):730.[doi:10.13798/j.issn.1009-153X.2015.12.008]
　YING Jian-you,TAN Zhan-guo,TAN Ao-yong,et al.Microsurgery for intracranial giant meningiomas (report of 12 cases)[J].,2015,(10):730.[doi:10.13798/j.issn.1009-153X.2015.12.008]
[3]张　双　骆　静　袁国艳　张振宇　张作洪　赵信德　柯以铨　张旺明.手术治疗桥小脑角区大型脑膜瘤9例[J].中国临床神经外科杂志,2019,(12):762.[doi:10.13798/j.issn.1009-153X.2019.12.015]

更新日期/Last Update: 1900-01-01