[1]晁晓峰,冯倚帆,黄天宁,等.颅脑术后继发颅内多重耐药鲍曼不动杆菌感染的危险因素[J].中国临床神经外科杂志,2022,27(06):471-473.[doi:10.13798/j.issn.1009-153X.2022.06.012]
　CHAO Xiao-feng,FENG Yi-fan,HUANG Tian-ning,et al.Risk factors for postoperative intracranial infection of multi-drug resistant Acinetobacter baumannii[J].,2022,27(06):471-473.[doi:10.13798/j.issn.1009-153X.2022.06.012]
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颅脑术后继发颅内多重耐药鲍曼不动杆菌感染的危险因素()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
27
期数:
2022年06期
页码:
471-473
栏目:
论著
出版日期:
2022-06-30

文章信息/Info

Title:
Risk factors for postoperative intracranial infection of multi-drug resistant Acinetobacter baumannii
文章编号:
1009-153X(2022)06-0471-03
作者:
晁晓峰; 冯倚帆; 黄天宁; 柳叶; 卫荣远; 于如同; 聂耳
221000 江苏徐州，徐州医科大学附属医院神经外科（晁晓峰、于如同、聂耳），检验科（冯倚帆）；221000 江苏徐州，徐州医科大学第一临床学院（黄天宁、柳叶、卫荣远）
Author(s):
CHAO Xiao-feng1;  FENG Yi-fan2;  HUANG Tian-ning3;  LIU Ye3;  WEI Rong-yuan3;  YU Ru-tong1;  NIE Er1
1.Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China; 2.Department of Laboratory, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China; 3.The First Clinical College, Xuzhou Medical Universi
关键词:
颅脑手术; 术后颅内感染; 鲍曼不动杆菌; 多重耐药菌; 危险因素
Keywords:
Craniotomy;  Postoperative intracranial infection;  Acinetobacter baumannii;  Multi-drug resistance;  Risk factors
分类号:
R651.1+1;R619+.3
DOI:
10.13798/j.issn.1009-153X.2022.06.012
文献标志码:
A
摘要:
目的 探讨颅脑术后继发颅内多重耐药（MDR）鲍曼不动杆菌（AB）感染的危险因素。方法 回顾性分析2015年1月至2020年6月收治的1 586例颅脑术后颅内感染的临床资料。根据脑脊液培养结果确定颅内感染病原体。结果 脑脊液培养显示AB感染124例，其中MDR-AB共99例。颅内AB感染的发生率为7.82%（124/1586），颅内MDR-AB感染的发生率为6.24%（99/1586），占颅内AB感染的79.84%。多因素logistic回归分析显示，入住ICU、肺部MDR-AB感染、开颅手术>1次是颅内MDR-AB感染的独立危险因素（P<0.05）。结论 颅内MDR-AB感染是临床治疗的难题，预防MDR-AB感染对改善颅脑手术病人的预后具有重要意义。缩短ICU入住时间、改善ICU条件对预防颅内MDR-AB感染具有重要意义。
Abstract:
Objective To explore the risk factors for postoperative intracranial infection of multi-drug resistant (MDR) Acinetobacter baumannii (AB). Methods A retrospective analysis was perofrmed on the clinical data of 1 586 patients with intracranial infection who underwent craniotomy from January 2015 to June 2020. The pathogen of intracranial infection was identified based on cerebrospinal fluid (CSF) culture. Results CSF culture showed AB infection in 124 patients, including 99 patients of MDR-AB. The incidence of intracranial AB infection was 7.82% (124/1586), and the incidence of intracranial MDR-AB infection was 6.24% (99/1586) accounting for 79.84% of intracranial AB infection. Multivariate logistic regression analysis showed that admission to ICU, pulmonary MDR-AB infection, and craniotomy>1 time were independent risk factors for intracranial MDR-AB infection (P<0.05). Conclusions Intracranial MDR-AB infection is a difficult problem in clinic. Prevention of MDR-AB infection is of great significance to improve the prognosis of patients undergoing craniotomy. Shortening ICU stay and improving ICU conditions are of great significance for preventing intracranial MDR-AB infection.

参考文献/References:

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备注/Memo

备注/Memo:
（2021-11-02收稿，2022-06-12修回）
基金项目：国家自然科学基金（81802490）
通讯作者：聂耳，E-mail：drnieer@163.com
更新日期/Last Update: 2022-07-31