[1]俞　洁,纪媛媛,王　军.神经外科重症监护室病人继发中枢神经系统感染的相关危险因素[J].中国临床神经外科杂志,2019,(04):204-206.[doi:10.13798/j.issn.1009-153X.2019.04.005]
　YU Jie,JI Yuan-yuan,WANG Jun..Analysis of risk factors related central nervous system infection in patients in neurosurgical intensive care unit[J].,2019,(04):204-206.[doi:10.13798/j.issn.1009-153X.2019.04.005]
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神经外科重症监护室病人继发中枢神经系统感染的相关危 险因素()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2019年04期
页码:
204-206
栏目:
论著
出版日期:
2019-04-27

文章信息/Info

Title:
Analysis of risk factors related central nervous system infection in patients in neurosurgical intensive care unit
文章编号:
1009-153X（2019）04-0204-03
作者:
俞　洁; 纪媛媛; 王　军
100053 北京，首都医科大学宣武医院神经外科（俞　洁、纪媛媛、王　军）
Author(s):
YU Jie;  JI Yuan-yuan;  WANG Jun.
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
关键词:
神经外科重症监护病房; 中枢神经系统感染; 危险因素
Keywords:
Neurosurgical intensive care unit;  CNS infection;  Risk factors
分类号:
R 651
DOI:
10.13798/j.issn.1009-153X.2019.04.005
文献标志码:
A
摘要:
目的 探讨神经外科重症监护室（NICU）病人发生中枢神经系统感染（CNSI）的危险因素。方法 回顾性分析2016年1~12月入住NICU的853例神经外科重症病人的临床资料，采用多因素Logistic 回归分析检验危险因素。结果 853例中，发生CNSI 31例，发生率为3.63%。多因素Logistic回归分析结果显示，年龄<60岁、白细胞减少、幕下开颅手术、放置引流管是NICU病人发生CNSI的独立危险因素 （P<0.05）。结论 NICU病人继发CNSI的危险因素众多，临床应密切关注，早做防范。
Abstract:
Objective To analyze the risk factors of nosocomial acquired central nervous system (CNS) infection in the patients in neurosurgical intensive care unit (NICU). Methods The clinical data of 853 patients who were treated in the NICU from January to December, 2016 were analyzed retrospectively. The risk factors related to CNS infection were statistically analyzed. Results CNS infection occurred in 31 (3.63%) of 853 patients. Univariate analysis showed that the factors related to CNS infection in those patients included the patients’ age, activities of daily living (ADL) score on admission, emergency admission, leukopenia, hyperglycemia, surgery, subtentorial craniotomy, operation duration >4 hours, non type I incision, intraoperative blood loss ≥ 1 000 ml, drainage tube placement, lumbar cistern drainage and drainage tube placement ≥3 days. Multivariate analysis showed that the independent risk factors of CNS infection in neurological ICU patients included the patients’ age <60 years old (P<0.01), leukopenia (P<0.01), subtentorial craniotomy (P<0.01) and drainage tube placement (P<0.01). Conclusion The patients with the above risk factors should be paid close attention to and take precautions of CNS infection as early as possible.

参考文献/References:

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备注/Memo

备注/Memo:
（2018-12-25收稿，2019-01-21修回）
更新日期/Last Update: 2019-04-27