[1]黄德俊,孙阳阳,万定,等.颅内破裂动脉瘤血管内介入治疗时机的选择及其对病人预后的影响[J].中国临床神经外科杂志,2022,27(08):637-639.[doi:10.13798/j.issn.1009-153X.2022.08.004]
　HUANG De-jun,SUN Yang-yang,WAN Ding,et al.Timing of endovascular intervention for patients with ruptured intracranial aneurysm and its effect on patients' prognoses[J].,2022,27(08):637-639.[doi:10.13798/j.issn.1009-153X.2022.08.004]
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颅内破裂动脉瘤血管内介入治疗时机的选择及其对病人预后的影响()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
27
期数:
2022年08期
页码:
637-639
栏目:
论著
出版日期:
2022-08-31

文章信息/Info

Title:
Timing of endovascular intervention for patients with ruptured intracranial aneurysm and its effect on patients' prognoses
文章编号:
1009-153X(2022)08-0637-03
作者:
黄德俊; 孙阳阳; 万定; 冯进; 杨振兴; 李小龙; 尹姬
750004 银川，宁夏医科大学总医院神经外科（黄德俊、万定、冯进、杨振兴），介入放射科（尹姬）；750004 银川，宁夏医科大学研究生院（孙阳阳、李小龙）
Author(s):
HUANG De-jun1;  SUN Yang-yang2;  WAN Ding1;  FENG Jin1;  YANG Zhen-xing1;  LI Xiao-long2;  YU Ji3
1. Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China; 2. Graduate School of Ningxia Medical University, Yinchuan 750004, China; 3. Department of Interventional Radiology, General Hospital of Ningxia Medical University, Yinchuan 750004, China
关键词:
颅内破裂动脉瘤; 蛛网膜下腔出血; 血管内治疗; 预后; 手术时机
Keywords:
Ruptured intracranial aneurysm;  Subarachnoid hemorrhage;  Endovascular treatment;  Prognosis;  Surgical timing
分类号:
R743.9;R815.2
DOI:
10.13798/j.issn.1009-153X.2022.08.004
文献标志码:
A
摘要:
目的 探讨颅内破裂动脉瘤血管内介入治疗时机的选择及其对病人预后的影响。方法 回顾性分析2018年1月至2020年6月血管内介入治疗的149例颅内破裂动脉瘤的临床资料。手术时机分为早期手术（≤72 h）和晚期手术（>72 h）。术后随访6个月，采用改良Rankin量表（mRS）评分评估预后，其中0~2分为预后良好，3~6分为预后不良。结果 术后6个月，110例（73.8%）预后良好；39例（26.2%）预后不良，其中死亡12例。本文149例中，早期手术96例，晚期手术53例。早期手术预后良好率（82.3%，79/96）明显高于晚期手术（55.4%，31/56；P<0.05）。多因素logistic回归分析显示，晚期手术是颅内破裂动脉瘤预后不良的独立危险因素（P<0.05）。结论 对于颅内破裂动脉瘤，早期手术可改善病人的预后。
Abstract:
Objective To investigate the Timing of endovascular intervention for patients with ruptured intracranial aneurysm (RIA) and its effect on patients' prognoses. Methods The clinical data of 149 patients with RIA who underwent endovascular embolization from January 2018 to June 2020 were analyzed retrospectively. The timing of embolization was classified as early embolization (≤72 h) and late embolization (>72 h). The patients were followed up for 6 months, and the patients' prognoses were assessed by the modified Rankin Scale (mRS) score, with a mRS score of 0~2 as good prognosis and score of 3~6 as poor prognosis. Results Of 149 patients, 110 patients (73.8%) had good prognoses and 39 (26.2%) poor prognoses, including 12 deaths. Of these 149 patients, 96 patients received early embolization and 53 late embolization. The good prognosis rate of patients undergoing early surgery (82.3%, 79/96) was significantly higher than that of patients undergoing late surgery (55.4%, 31/56; P<0.05). Multivariate logistic regression analysis showed that late embolization was an independent risk factor for poor prognosis of patients with ruptured intracranial aneurysm (P<0.05). Conclusions Early endovascular embolization can improve the prognoses of patients with RIA.

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备注/Memo

备注/Memo:
（2021-09-02收稿，2022-07-24修回）
基金项目：宁夏回族自治区科学技术厅重点研发项目（2018YBZD0034）
通信作者：黄德俊，E-mail：hdj1225@163.com
更新日期/Last Update: 2022-09-30