[1]张果,秦小宏,程荆,等.脑血运重建术治疗成人脑底异常血管网病的疗效分析[J].中国临床神经外科杂志,2023,28(02):65-68.[doi:10.13798/j.issn.1009-153X.2023.02.001]
　ZHANG Guo,QIN Xiao-hong,CHEN Jin,et al.Short-term efficacy of STA-MCA bypass combined with ence-phalo-myo-synangiosis for adult moyamoya diseases: single-vessel bypass vs. double-vessel bypass[J].,2023,28(02):65-68.[doi:10.13798/j.issn.1009-153X.2023.02.001]
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脑血运重建术治疗成人脑底异常血管网病的疗效分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
28
期数:
2023年02期
页码:
65-68
栏目:
论著
出版日期:
2023-02-28

文章信息/Info

Title:
Short-term efficacy of STA-MCA bypass combined with ence-phalo-myo-synangiosis for adult moyamoya diseases: single-vessel bypass vs. double-vessel bypass
文章编号:
1009-153X（2023）02-0065-04
作者:
张果; 秦小宏; 程荆; 吴明洪; 张文斐; 吴立权; 陈治标
430060武汉，武汉大学人民医院神经外科（张果、秦小宏、程荆、吴明洪、张文斐、吴立权、陈治标）
Author(s):
ZHANG Guo;  QIN Xiao-hong;  CHEN Jin;  WU Ming-hong;  ZHANG Wen-fei;  WU Li-quan;  CHEN Zhi-biao
Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
关键词:
脑底异常血管网病; 烟雾病; 血运重建术; 颞肌贴敷术; 颞浅动脉; 大脑中动脉; 疗效
Keywords:
Moyamoya disease;  Superficial temporal artery-middle cerebral artery bypass;  Ence-phalo-myo-synangiosis;  Prognosis;  Double-vessel bypass;  Single-vessle bypass
分类号:
R744.1;R651.1+2
DOI:
10.13798/j.issn.1009-153X.2023.02.001
文献标志码:
A
摘要:
目的 探讨颞浅动脉（STA）-大脑中动脉（MCA）分流术联合颞肌贴敷术治疗脑底异常血管网病（MMD）时单支血管分流术与双支血管分流术的疗效差异。方法 2020年1月至2022年6月前瞻性收治符合标准的MMD共59 例，37例应用STA-MCA单支血管分流术联合颞肌贴敷术治疗（单支分流组），22例应用STA-MCA双支血管分流术联合颞肌贴敷术治疗（双支分流组）。结果 术后3个月DSA或CTA显示分流血管通畅，其中分流血管显影良好38例；49例（83.1%）神经功能改善（手术前后mRS评分差值>0），47例（79.7%）脑组织血供改善（手术前后脑灌注评分差值<0）；未发生手术相关并发症。两组术后3个月mRS评分及脑灌注评分均明显改善（P<0.05），而且，双支血管分流组明显优于单支血管分流组（P<0.05）。双支血管分流组术后mRS评分改善率、脑灌注评分改善率均明显高于单支血管分流组（P<0.05）。结论 STA-MCA分流术联合颞肌贴敷术治疗MMD疗效良好，而且双支血管分流术的短期预后优于单支血管分流术。
Abstract:
Objective To analyze the short-term prognosis of superficial temporal artery (STA)-middle cerebral artery (MCA) combined with ence-phalo-myo-synangiosis for patients with moyamoya disease (MMD). Methods A total of 59 patients with MMD were prospectively recruited from January 2020 to June 2022. Thirty-seven patients were treated with STA-MCA single-vessel bypass combined with ence-phalo-myo-synangiosis (single bypass group), and 22 patients were treated with STA-MCA double-vessel bypass combined with ence-phalo-myo-synangiosis (double bypass group). Results Three months after the operation, DSA or CTA showed patency in all bypass vessels. Neurological function was improved ( with a difference of mRS score before and after operation >0) in 49 patients (83.1%), and brain tissue blood supply was improved ( with a difference of cerebral perfusion score before and after surgery <0) in 47 patients (79.7%). There were no surgery-related complications. The mRS and cerebral perfusion scores were significantly improved in both groups 3 months after the surgery (P<0.05), and they were significantly better in the double bypass group than those in the single bypass group (P<0.05). The improvement rates of mRS score and cerebral perfusion score in the double bypass group were significantly higher than those in the single bypass group (P<0.05). Conclusions STA-MCA bypass combined with ence-phalo-myo-synangiosis is effective for treating MMD, and the short-term prognosis of double-vessel bypass is better than that of the single-vessle bypass.

参考文献/References:

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备注/Memo

备注/Memo:
（2023-01-12收稿，2023-01-28修回）
基金项目：国家自然科学基金（82201515）；湖北省自然科学基金（2021CFB057）
通讯作者：陈治标，E-mail：chzbiao@126.com
更新日期/Last Update: 2022-03-31