[1]熊海兵,熊浩锋,霍建宏,等.脑实质内孤立性纤维性肿瘤1例[J].中国临床神经外科杂志,2024,29(11):702-704.[doi:10.13798/j.issn.1009-153X.2024.11.016]
　XIONG Hai-bing,XIONG Hao-feng,HUO Jian-hong,et al.Solitary fibrous tumor within the brain parenchyma: a case report[J].,2024,29(11):702-704.[doi:10.13798/j.issn.1009-153X.2024.11.016]
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脑实质内孤立性纤维性肿瘤1例()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
29
期数:
2024年11期
页码:
702-704
栏目:
个案报道
出版日期:
2024-11-30

文章信息/Info

Title:
Solitary fibrous tumor within the brain parenchyma: a case report
文章编号:
1009-153X（2024）11-0702-03
作者:
熊海兵; 熊浩锋; 霍建宏; 曾实
401320重庆，重庆医科大学附属巴南医院神经外科（熊海兵、熊浩峰、霍建宏、曾实）
Author(s):
XIONG Hai-bing;  XIONG Hao-feng;  HUO Jian-hong;  ZENG Shi
Department of Neurosurgery, Ba'nan Hospital Affiliated to Chongqing Medical University,Chongqin 401320, China
关键词:
脑内肿瘤; 孤立性纤维性肿瘤; 额叶; 显微手术
Keywords:
Intracranial tumor;  Solitary fibrous tumor;  Frontal lobe;  Microsurgery
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2024.11.016
文献标志码:
B
摘要:
孤立性纤维性肿瘤（SFT）是一种起源于CD34抗原的树突状间充质细胞的梭形细胞肿瘤，可发生在全身任何部位，以胸腹部多见，颅内少见。尽管SFT从病理学上被定义为间叶性非脑膜性肿瘤，但颅内SFT一般沿着脑膜生长，术前易误诊为脑膜瘤。脑实质内SFT临床罕见。本文报道1例左侧额叶SFT，为56岁男性，因头晕1个月、检查发现颅内占位1周入院，无明显神经系统阳性体征。头颅CT、MRI显示左侧额叶占位性病变。在全麻下，行左侧额叶病灶切除术。术中发现肿瘤位于左侧额叶白质内，质韧，边界清楚。术后病理检查显示SFT（WHO分级Ⅰ级）。术后3个月复查头颅MRI未见肿瘤复发。总之，脑实质内SFT罕见，大多良性生长，临床误诊率高，影像学检查有一定特异性，确诊主要靠病理诊断，手术全切除肿瘤是主要治疗方法，一般预后较好。
Abstract:
Solitary fibrous tumor (SFT) is a spindle cell tumor originated from CD34-positive dendritic mesenchymal cells, which can occur in multiple parts of the body, most commonly in the thorax and abdomen, and is relatively rare in the brain. Although SFT is pathologically defined as a mesenchymal non-meningeal tumor, intracranial SFT usually grows along the meninges and is often misdiagnosed as meningioma before surgery. SFT within the brain parenchyma is even rarer. This paper reports a case of a 56-year-old male with a solitary fibrous tumor in the left frontal lobe. He was admitted to the hospital due to dizziness for one month and a space-occupying lesion in the brain was found one week ago. There were no obvious positive neurological signs. Head CT and MRI showed a space-occupying lesion in the left frontal lobe. Under general anesthesia, a left frontal lobe lesion resection was performed. During the operation, the tumor was found to be located in the white matter of the left frontal lobe, with a tough texture and clear boundaries. Postoperative pathological examination confirmed SFT (WHO grade I). Three months after the operation, a head MRI review showed no tumor recurrence. In conclusion, SFT within the brain parenchyma is extremely rare, mostly benign, with a high rate of clinical misdiagnosis. Imaging examinations have certain specificity, and the diagnosis depends on pathological examination. Surgical total resection is the main treatment method, and the prognosis is generally good.

参考文献/References:

[1] DAVANZO B, EMERSON RE, LISY M, et al. Solitary fibrous tumor [J]. Transl Gastroenterol Hepatol, 2018, 3: 94.
[2] COHEN-INBAR O. Nervous system hemangiopericytoma [J]. Can J Neurol Sci , 2020, 47(1): 18-29.
[3] TARIQ MU, DIN NU, ABDUL-GHAFAR J, et al. The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior [J]. Diagn Pathol, 2021, 16(1): 1-14.
[4] GIORDAN, E, MARTON, E, WENNBERG, AM, et al. A review of solitary fibrous tumor/hemangiopericytoma tumor and a comparison of risk factors for recurrence, metastases, and death among patients with spinal and intracranial tumors [J]. Neurosurg Rev, 2021, 44(3): 1299-1312.
[5] MARTIN-BROTO J, MONDAZA-HERNANDEZ JL, MOURA DS, et al. A comprehensive review on solitary fibrous tumor: new insights for new horizons [J]. Cancers (Basel), 2021, 13(12): 2913.
[6] SHIN DW, KIM JH, CHONG S, et al. Intracranial solitary fibrous tumor/hemangiopericytoma: tumor reclassification and assessment of treatment outcome via the 2016 WHO classification [J]. J Neurooncol, 2021, 154(2): 171-178.
[7] KIM BS, KIM Y, KONG DS, et al. Clinical outcomes of intracranial solitary fibrous tumor and hemangiopericytoma: analysis according to the 2016 WHO classification of central nervous system tumors [J]. J Neurosurg, 2018, 129(6): 1384-1396.
[8] HUANG DY, HUANG C, MA DZ. Progress in imaging diagnosis of intracranial solitary fibrous tumors [J]. Chin Youjiang Med J, 2020, 48(4): 307-310. 黄德尤，黄　策，马德智. 颅内孤立性纤维瘤的影像学诊断进展[J]. 右江医学，2020，48（4）：307-310.
[9] GOPAKUMAR S, SRINIVASAN VM, HADLEY CC, et al. Intracranial solitary fibrous tumor of the skull base: 2 cases and systematic review of the literature [J]. World Neurosurg, 2021, 149: e345-e359.

相似文献/References:

[1]王林风.颅内孤立性纤维性肿瘤1例[J].中国临床神经外科杂志,2015,(08):462.[doi:10.13798/j.issn.1009-153X.2015.08.005]

备注/Memo

备注/Memo:
（2022-08-21收稿，2024-02-21修回）
通信作者：曾　实，Email：769595381@qq.com
更新日期/Last Update: 2024-11-30