[1]王重韧 赵 明 徐 欣 尤 宇 韩 磊 赵四军.症状型Rathke裂隙囊肿的临床特征及外科治疗(附13例报告)[J].中国临床神经外科杂志,2015,(04):214-216.[doi:10.13798/j.issn.1009-153X.2015.04.007]
 WANG Chong-ren,ZHAO Ming,XU Xin,et al.Clinical features and surgical treatment of symptomatic Rathke cleft cysts (report of 13 cases)[J].,2015,(04):214-216.[doi:10.13798/j.issn.1009-153X.2015.04.007]
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症状型Rathke裂隙囊肿的临床特征及外科治疗(附13例报告)()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年04期
页码:
214-216
栏目:
论著
出版日期:
2015-04-30

文章信息/Info

Title:
Clinical features and surgical treatment of symptomatic Rathke cleft cysts (report of 13 cases)
文章编号:
1009-153X(2015)04-0214-03
作者:
王重韧 赵 明 徐 欣 尤 宇 韩 磊 赵四军
450008 郑州,郑州大学附属肿瘤医院神经外科(王重韧、赵 明、徐 欣、尤 宇、韩 磊、赵四军)
Author(s):
WANG Chong-ren ZHAO Ming XU Xin YOU Yu HAN Lei ZHAO Si-jun.
Department of Neurosurgery, The Affiliated Tumor Hospital, Zhengzhou University, Zhengzhou 450008, China
关键词:
Rathke裂隙囊肿显微外科治疗经鼻蝶入路
Keywords:
Rathke cleft cyst Diagnosis Pituitary dysfunction Surgical treatment
分类号:
R739.41;R651.1+1
DOI:
10.13798/j.issn.1009-153X.2015.04.007
文献标志码:
A
摘要:
目的 探讨症状型Rathke裂隙囊肿的临床特点及手术治疗效果。方法 回顾性分析自2008年10月至2014年8月经手术治疗的13例症状型鞍区Rathke裂隙囊肿患者的临床资料,内镜下经鼻蝶入路11例,开颅显微手术2例,术中均清除囊内容物,囊内容物送细菌学培养,镜下完全(9例)或部分切除(4例)囊壁。结果 随访6个月~3年,术后头痛缓解率100%,视力障碍缓解率80%,内分泌功能紊乱症状得到不同程度的缓解。细菌培养阳性者4例,术后复发2例。结论 症状型Rathke裂隙囊肿临床表现无特异性,影像学表现多样,部分患者术前明确诊断较困难。手术应在充分减压的同时尽可能地切除囊壁,术中应对较为粘稠的囊内容物进行细菌培养,减少颅内感染及囊肿复发。
Abstract:
Objectives To analyze the clinical features and surgical outcomes of symptomatic Rathke cleft cysts (RCCs). Methods The clinical data of 13 patients with RCCs, of whom, 11 were treated by endoscope-assisted microsurgery via the transnasal transsphenoidal approach and 2 by microsurgery via the transcranial approach. The intracystic contents were completely removed and taken for bacterial culture in all the patients. The cystic walls were removed completely or partially during the surgery. Results The following-up from 6 month to 3 years showed that the headache remitted in 7 patients with preoperative headache (100%, 7/7), the visual disorder remitted in 4 patients with preoperative visual disorder (80%, 4/5) and the rate of endocrine function disorder remission was 59.1% (13 case-time /22 case-time). The bacterial culture was positive in 4 patients (30.8%). RCCs recurred after the surgery in 2 patients (15.4%). Conclusions It is difficult to make the definite diagnosis before the operation due to nonspecific clinical symptoms and image findings in all the patients with atypical RCCs. The cystic walls should be totally resected as possible by the surgery to prevent recurrence of the cysts in the patients with RCCs. The intracystic contents should be taken for bacterial culture to reduce the occurrence of intracranial infection and recurrence of RCCs.

参考文献/References:

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备注/Memo

备注/Memo:
通讯作者:赵 明,E-mail:zm6392@sina.com
更新日期/Last Update: 2016-04-25