[1]黄　斌　李全才　张庭荣　郭运发　吴　昊　罗　坤.内镜 下与显微镜下经蝶手术治疗症状性Rathke囊肿的对比分析[J].中国临床神经外科杂志,2016,(05):264-266.[doi:10.13798/j.issn.1009-153X.2016.05.003]
　HUANG Bin,LI Quan-cai,ZHANG Ting-rong,et al.Surgery through transsphenoidal approach for symptomatic rathke cleft cysts: endoscopic surgery vs microsurgery[J].,2016,(05):264-266.[doi:10.13798/j.issn.1009-153X.2016.05.003]
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内镜 下与显微镜下经蝶手术治疗症状性Rathke 囊肿的对比分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2016年05期
页码:
264-266
栏目:
论著
出版日期:
2016-05-25

文章信息/Info

Title:
Surgery through transsphenoidal approach for symptomatic rathke cleft cysts: endoscopic surgery vs microsurgery
文章编号:
1009-153X（2016）05-0264-03
作者:
黄　斌　李全才　张庭荣　郭运发　吴　昊　罗　坤
作者单位：830054 乌鲁木齐，新疆医科大学第一附属医院神经外科 （黄　斌、李全才、张庭荣、郭运发、吴　昊、罗　坤）
Author(s):
HUANG Bin;  LI Quan-cai;  ZHANG Ting-rong;  GUO Yun-fa;  WU Hao;  LUO Kun
Department of Neurosurgery, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, China
关键词:
Rathke囊肿; 内镜; 显微镜; 经蝶入路; 手术
Keywords:
Rathke cleft cyst;  Endoscope-assisted surgery;  Microsurgery;  Transsphenoidal approach;  Curative effects
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2016.05.003
文献标志码:
A
摘要:
目的 探讨内镜下与显微镜下经蝶手术治疗症状性Rathke囊肿的有效性和安全性。方法 2001~2015年收治症状性Rathke囊肿34例，显微镜下经鼻蝶手术12例（显微镜组），内镜下经鼻蝶手术22例（内镜组）。结果 两组术后头痛有效率均为100%；显微镜组术后视力改善率为88.9%（8/9），内镜组为83.3%（5/6），两组无明显差异（P>0.05）；显微镜组术后并发症发生率（16.7%）和复发率（8.3%）与内镜组（分别为13.5%和4.5%）均无明显差异（P>0.05）。结论 症状性Rathke囊肿的经蝶手术可以借助内镜切除肿瘤也可以借助显微镜下切除，两种手术方法疗效没有明显差异。
Abstract:
Objective To compare effect of endoscope-assisted transsphenoidal surgery on symptomatic Rathke cleft cysts and its safety with those of microsurgery. Methods The clinical data of 34 patients with symptomatic Rathke cleft cysts, of whom, 22 underwent endoscope-assisted transsphenoidal surgery and 12 transsphenoidal microsurgery from 2001 to 2015, were analyzed retrospectively. All the patients were followed up for 5 years. Results There were insignificant differences in the curative effects and postoperative complication occurrence rate between both the groups (P>0.05). But the average hospital stay [(10.67±2.27) days] after the operation in the microsurgery group was significantly more than that [(7.77±1.82) days] in the endoscopic group (P<0.01).>Conclusions The curative effects of endoscope-assisted transsphenoidal surgery and transsphenoidal microsurgery on symptomatic Rathke cleft cysts and their safety are good, but the hospital stay after the operation may be reduced in the patients with symptomatic Rathke cleft cysts undergoing endoscope-assisted transsphenoidal surgery compared to that in the patients undergoing transsphenoidal microsurgery.

参考文献/References:

[1] 王忠诚. 王忠诚神经外科学[M]. 第1版. 武汉：湖北科学 技术出版社， 2005. 634-635.
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[3] Voelker JL, Campbell RL, Muller J. Clinical, radiographic, and pathological features of symptomatic Rathke’s cleft cysts [J]. J Neurosurg, 1991, 74(4): 535-544.
[4] Aho CJ, Liu C, Zelman V, et al. Surgical outcomes in 118 patients with Rathke cleft cysts [J]. J Neurosurg, 2005, 102 (2): 189-193.
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[6] Pawar SJ, Sharma RR, Lad SD, et al. Rathke’s cleft cyst presenting as pituitary apoplexy [J]. J Clin Neurosci, 2002, 9 (1): 76-79.
[7] Xie T, Hu F, Yu Y, et al. Endoscopic endonasal resection of symptomatic Rathke cleft cysts [J]. J Clin Neurosci, 2011, 18(6): 760-762.
[8] Frank G, Sciarretta V, Mazzatenta D, et al. Transsphenoidal endoscopic approach in the treatment of Rathke’s cleft cyst [J]. Neurosurgery, 2005, 56(1): 124-129.
[9] Madhok R, Prevedello D M, Gardner P, et al. Endoscopic endonasal resection of Rathke cleft cysts: clinical outcomes and surgical nuances [J]. J Neurosurg, 2010, 112(6): 1333- 1339.
[10] Koutourousiou M, Grotenhuis A, Kontogeorgos G, et al. Treatment of Rathke’s cleft cysts: experience at a single centre [J]. J Clin Neurosci, 2009, 16(7): 900-903.
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备注/Memo

备注/Memo:
基金项目：新疆维吾尔自治区高技术研究发展项目（201417103）
通讯作者：罗　坤，E-mail：luokun-2822@sohu.com
更新日期/Last Update: 2016-05-30