[1]贺瑛福　肖宗宇　马进海　许常林　裴　杰　袁　岗　张广华　 巨　虎.高海拔地区重型颅脑损伤血清FSH、LH、PRL的变化[J].中国临床神经外科杂志,2016,(06):359-361.[doi:10.13798/j.issn.1009-153X.2016.06.013]
　HE Ying-fu,XIAO Zong-yu,MA Jin-hai,et al.Changes in serum FSH, LH and PRL levels in the patients with severe traumatic brain injury in plateau[J].,2016,(06):359-361.[doi:10.13798/j.issn.1009-153X.2016.06.013]
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高海拔地区重型颅脑损伤血清FSH、LH、PRL的变化()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2016年06期
页码:
359-361
栏目:
论著
出版日期:
2016-06-25

文章信息/Info

Title:
Changes in serum FSH, LH and PRL levels in the patients with severe traumatic brain injury in plateau
文章编号:
1009-153X（2016）06-0359-03
作者:
贺瑛福　肖宗宇　马进海　许常林　裴　杰　袁　岗　张广华　 巨　虎
810001西宁，青海大学医学院附属医院神经外科（贺瑛福、肖宗宇、马进海、许常林、裴　杰、袁　岗 、张广华 、巨　虎）
Author(s):
HE Ying-fu;  XIAO Zong-yu;  MA Jin-hai;  XU Chang-lin;  PEI Jie;  YUAN Gang;  ZHANG Guang-hua;  JU Hu.
Department of Neurosurgery, Affiliated Hospital, Qinghai University, Xi’ning 810001, China
关键词:
颅脑损伤; 高海拔地区; 内分泌激素; 血清水平; 促卵泡生长素; 促黄体生成素; 催乳素
Keywords:
Severe traumatic brain injury;  FSH;  LH;  PRL;  Serum levels
分类号:
R 651.1+5
DOI:
10.13798/j.issn.1009-153X.2016.06.013
文献标志码:
A
摘要:
目的 探讨高海拔地区重型颅脑损伤内分泌激素水平的变化规律，为提高高海拔地区重型颅脑损伤的治疗效果提供帮助。方法 2012年1月至2013年12月收治高海拔地区颅脑损伤120例，其中重型颅脑损伤（入院时GCS评分3~8分）60例，轻型颅脑损伤（入院时GCS评分13~15分）60例。伤后1、3、7、14、21 d应用放射免疫定量分析法检测血清促卵泡生长素（FSH）、促黄体生成素（LH）、催乳素（PRL）水平。结果 伤后1、3、7、14、21 d，重型颅脑损伤血清FSH、LH水平与与轻型颅脑损伤相比无显著性变化（P>0.05）；而PRL水平在伤后1 d有显著变化（P <0.05），以后无显著性差异（P>0.05）。结论 高海拔地区重型颅脑损伤血清PRL有轻微变化，而血清FSH、LH的水平无显著性变化。
Abstract:
Objective To explore the change in endocrine hormone in the patients with severe traumatic brain injury in the plateau. Methods The serum levels of FSH, LH and PRL were determined by quantitative radioimmunoassay method in 60 patients with severe traumatic brain injury and 60 patients with mild traumatic brain injury 1, 3, 7, 14 and 21 days after the injury and were statistically analyzed. Results There were insignificant differences in the serum levels of FSH and LH between the patients with severe traumatic brain injury and the patients with mild traumatic brain injury 1, 3, 7, 14 and 21 days after the injury (P>0.05). The serum levels of PRL were significantly higher in the patients with severe brain injury than that in the patients with mild brain injury 1 day after the injury (P <0.05). Conclusions The serum level of PRL may be increased 1 day after the injury in the patients with severe traumatic brain injury compared to that in the patients with mild traumatic brain injury. But there were insignificant changes in the serum levels of FSH and LH in the patients with severe brain injury compared to that the patients with mild brain injury 1, 3, 7, 14 and 21 days after the injury.

参考文献/References:

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更新日期/Last Update: 2016-06-20