[1]陈燕豪,岑卓英,梁春妍,等.高血压性脑出血早期血肿扩大与血压变异性的关系[J].中国临床神经外科杂志,2017,(02):80-82.[doi:10.13798/j.issn.1009-153X.2017.02.006]
 CHEN Yan-hao,CEN Zhuo-ying,LIANG Chun-yan,et al.Relationship of hematoma enlargement with blood pressure variability early after hypertensive intracerebral hemorrhage[J].,2017,(02):80-82.[doi:10.13798/j.issn.1009-153X.2017.02.006]
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高血压性脑出血早期血肿扩大与血压变异性的关系()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年02期
页码:
80-82
栏目:
论著
出版日期:
2017-02-20

文章信息/Info

Title:
Relationship of hematoma enlargement with blood pressure variability early after hypertensive intracerebral hemorrhage
文章编号:
1009-153X(2017)02-0089-03
作者:
陈燕豪岑卓英梁春妍钟建东林国庆
作者单位:524400 广东,廉江市人民医院神经外科(陈燕豪、岑卓英、梁春妍、钟建东、林国庆)
Author(s):
CHEN Yan-hao CEN Zhuo-ying LIANG Chun-yan ZHONG Jian-guo LIN Guo-qing.
Department of Neurosurgery, Lianjiang Municipal People’s Hospital, Lianjiang 524400, China
关键词:
高血压性脑出血早期血肿扩大血压变异性相关性
Keywords:
Hypertensive intracerebral hemorrhage Hematoma enlargement Blood pressure variability Relationship
分类号:
R 743.34
DOI:
10.13798/j.issn.1009-153X.2017.02.006
文献标志码:
A
摘要:
目的 探讨高血压性脑出血早期血肿扩大与血压变异性(BPV)的关系。方法 2014年4月到2016年5月收治高血压性脑出血100例,入院后行24 h血压动态监测;根据CT检查结果将100例分为血肿扩大组(30例)和非血肿扩大组(70例);采用条件Logistic回归分析检验早期血肿扩大与BPV的关系。结果 血肿扩大组最大收缩压(SBP)、平均SBP均明显高于非血肿扩大组(P<0.05),两组最大舒张压(DBP)、平均DBP、SBP标准差(SD)、DBP SD、SBP变异系数(CV)、DBP CV均无统计学差异(P>0.05);血肿扩大组血肿增大比例[(52.31±3.48)%]、血肿体积[(16.78±2.35)ml]均明显高于非血肿扩大组[分别为(23.18±2.89)%和(7.48±1.28)ml;P<0.05]。Logistic回归分析结果显示,最大SBP、平均SBP是血肿扩大的独立危险因素(P<0.05)。结论 高血压性脑出血后24 h内血肿扩大与BPV无明显关系,而与SBP变化有关。
Abstract:
Objective To investigate the relationship of hematoma enlargement with blood pressure variability (BPV) early after hypertensive intracerebral hemorrhage (HICH). Methods Of 100 patients with HICH treated in our hospital from April, 2014 to May, 2016, 30 had hematoma enlargement and 70 did not 24 hours after admission to hospital. Detection of ECG, drug therapy, 24 hours dynamic detection of blood pressure and quantitative determination of changes in the hematoma volume with CT were performed after the admission to hospital in all the patients. Results The dynamic detection of 24 hours blood pressure showed that the maximal systolic blood pressure (SBP) and mean SBP were significantly higher in the patients with hematoma enlargement than those in the patients without hematoma enlargement (P<0.05). There were no significant differences in the maximal and mean diastolic blood pressure (DBP), SBP coefficient of variability (CV) and DBP CV between the hematoma enlargement and no hematoma enlargement groups (P>0.05). Logistic regression analysis showed that the independent risk factors for hematoma enlargement included the maximal and mean SBP (OR=1.388, OR=1.230, respectively; P<0.05). Conclusions The mean and maximal SBP are the independent risk factors for hematoma enlargement within 24 hours after the admission to hospital in the patients with HICH. There is no significant correlationship between BPV and hematoma enlargement.

参考文献/References:

[1] Zou M, Yan T. Association of blood pressure variability and early enlargement of hematoma in acute intracerebral hemorrhage patients treated with early intensive blood pre- ssure lowering treatment [J]. Cerebrovas Dis, 2012, 34(1): 11.
[2] Manning L, Hirakawa Y, Arima H, et al. Blood pressure variability and outcome after acute intracerebral haemo- rrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial [J]. Lancet Neurol, 2014, 13(4): 364-373.
[3] 贺 丹,丁世彬. 脑出血病人脑血肿面积与血压的相关性 分析[J]. 中西医结合心脑血管病杂志,2016,14(12): 1419-1420.
[4] Jialan Sun MM, Wanlin Yang MM, Yang ZB, et al. The rela- tionship between nocturnal blood pressure and hemorrhagic stroke in chinese hypertensive patients [J]. J Clin Hypertens (Greenwich), 2014, 16(9): 652-657.
[5] Mccourt R, Gould B, Gioia L, et al. Cerebral perfusion and blood pressure do not affect perihematoma edema growth in acute intracerebral hemorrhage [J]. Stroke, 2014, 45(5): 1292-1298.
[6] 孙奉辉,徐依成,陈新平,等. 高血压脑出血血肿周围水肿 与动态血压的相关性研究[J]. 中华老年心脑血管病杂 志,2016,18(6):571-573.
[7] 李海燕,高崇恒,樊丹娜,等. 急诊干预对防止脑出血后早 期血肿扩大的临床意义[J]. 中华全科医学,2014,12 (10):84-85.
[8] 王 伟. 早期血压变异性对重症高血压脑出血患者预后 的探究[J]. 中国药物与临床,2016,16(6):884-886.
[9] 刘兵荣, 马继民, 肖 瑾,等. 脑血管CTA点征与高血压 脑出血患者早期血肿扩大关系的初步研究[J]. 中华全科 医学,2014,12(10):11-14.
[10] Chan E, Anderson C S, Wang X, et al. Significance of intra- ventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemo- rrhage trial results [J]. Stroke, 2015, 46(3): 653-658.
[11] 谢 嵘,李少平,丁天凌,等. 用凝血功能综合评分法分析 高血压脑出血急性期血肿扩大的相关因素 [J]. 中国临床 神经科学,2014,22(3):296-300.

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更新日期/Last Update: 1900-01-01