[1]肖高华 陈 钢 陈 峥 刘 科 刘 笑 熊绍棠.急性颅脑损伤外周血垂体前叶激素及脑脊液硫化氢水平变化[J].中国临床神经外科杂志,2017,(05):310-312.[doi:10.13798/j.issn.1009-153X.2017.05.009]
 XIAO Gao-hua,CHEN Zheng,CHEN Gang,et al.Changes of plasma anterior pituitary hormone and CSF H2S in patients with acute craniocerebral trauma[J].,2017,(05):310-312.[doi:10.13798/j.issn.1009-153X.2017.05.009]
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急性颅脑损伤外周血垂体前叶激素及脑脊液硫化氢水平变化()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年05期
页码:
310-312
栏目:
论著
出版日期:
2017-05-20

文章信息/Info

Title:
Changes of plasma anterior pituitary hormone and CSF H2S in patients with acute craniocerebral trauma
文章编号:
1009-153X(2017)05-0310-03
作者:
肖高华 陈 钢 陈 峥 刘 科 刘 笑 熊绍棠
434001 湖北,荆州市第三人民医院神经外科
Author(s):
XIAO Gao-hua CHEN Zheng CHEN Gang LIU Xiao LIU Ke XIONG Shao-tang.
Department of Neurosurgery, The Third People’s Hospital of Jingzhou City, Jingzhou 434001, China
关键词:
急性颅脑损伤垂体前叶激素外周血脑脊液硫化氢
Keywords:
Acute craniocerebral trauma Anterior pituitary hormone H2S Plasma Cerebrospinal fluid Level
分类号:
R 651.1+5
DOI:
10.13798/j.issn.1009-153X.2017.05.009
文献标志码:
A
摘要:
目的 探讨外周血垂体前叶激素、脑脊液硫化氢(H2S)水平与急性颅脑损伤病情的关系。方法 2014年3月至2015年11月收治急性颅脑损伤90例,根据入院时GCS评分分为轻型组(GCS评分13~15分)、中型组(GCS评分9~12分)及重型组(GCS评分3~8分),各30例。伤后1 d采集空腹静脉血测定促甲状腺激素(TSH)、泌乳素(PRL)、黄体生成素(LH)、促卵泡激素(FSH)、生长激素(GH),另外测定脑脊液H2S水平。结果 外周血GH、PRL水平以及脑脊液H2S水平随颅脑损伤程度加重明显增高(P<0.05),而外周血TSH、LH、FSH与颅脑损伤程度无明显相关性(P>0.05)。结论 外周血GH、PRL及脑脊液H2S水平可作为评估急性颅脑损伤病情的指标。
Abstract:
Objective To investigate the relationship of the severity with levels of anterior pituitary hormones (APHs) and cerebrospinal fluid (CSF) hydrogen sulfide (H2S) in patients with acute craniocerebral trauma (ACT). Methods Of 90 patients with ACT treated in the hospital from March, 2014, to November, 2015, 30 suffered from mild ACT, 30 from moderate ACT and 30 from severe ACT according to GCS. The levels of plasma APHs including thyroid-stimulating hormone (TSH), prolactin (PRL), luteotrophic hormone (LH), follicle-stimulating hormone (FSH) and growth hormone (GH) and CFS H2S were determined in all the patients 1 day after ACT. The relationship of severity with the levels of plasma APH and CSF H2S was analyzed. Results The levels of plasma GH and PRL and CFS H2S were significantly higher in the patients with severe ACT than those in the patients with moderate ACT (P<0.05), which were significantly higher than those in the patients with mild ACT (P<0.05). Conclusion It is suggested that the levels of plasma GH and PRL and CSF H2S which are positively related to the severity can be used as indicators of injury severity in the patients with ACT.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:湖北省自然科学基金(2012FFC060)
更新日期/Last Update: 2017-05-20