[1]唐玺和 唐秀文 蓝胜勇 肖 泉 庞 刚 钟 书 徐柯贝 徐 鹏.脑膜血管周细胞瘤的诊断及治疗(附8例分析[J].中国临床神经外科杂志,2017,(12):828-830.[doi:10.13798/j.issn.1009-153X.2017.12.009]
 TANG Xi-he,TANG Xiu-wen,LAN Sheng-yong,et al.Diagnosis and treatment of meningeal hemangiopericytomas (report of 8 cases)[J].,2017,(12):828-830.[doi:10.13798/j.issn.1009-153X.2017.12.009]
点击复制

脑膜血管周细胞瘤的诊断及治疗(附8例分析()
分享到:

《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年12期
页码:
828-830
栏目:
论著
出版日期:
2017-12-25

文章信息/Info

Title:
Diagnosis and treatment of meningeal hemangiopericytomas (report of 8 cases)
文章编号:
1009-153X(2017)12-0828-03
作者:
唐玺和 唐秀文 蓝胜勇 肖 泉 庞 刚 钟 书 徐柯贝 徐 鹏
作者单位:530021 南宁,广西壮族自治区人民医院神经外科(唐玺和、唐秀文、蓝胜勇、肖 泉、庞 刚、钟 书、徐柯贝、徐 鹏)
Author(s):
TANG Xi-he TANG Xiu-wen LAN Sheng-yong XIAO Quan PANG Gang ZHONG Shu XU Ke-bei XU Peng.
Department of Neurosurgery, People’s Hospital, Guangxi Zhuang Autonomous Region, Nanning 530021, China
关键词:
脑膜血管周细胞瘤诊断治疗放疗
Keywords:
Meningeal hemangiopericytomas Surgery Differential diagnosis Pathological diagnosis Radiotherapy
分类号:
R 739.41; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2017.12.009
文献标志码:
A
摘要:
目的 探讨脑膜血管周细胞瘤的诊断及治疗方法,以提高对该病的诊治水平。方法 回顾性分析2010年1月至2016年11月收治的8例脑膜血管周细胞瘤的临床资料。结果 肿瘤全切除7例,次全切除1例。术后病理检查光镜下可见瘤内血供丰富,瘤细胞弥漫生长,多梭形,染色质中等密度,核仁不明显,无脑膜瘤特异性的核仁假包涵体。免疫组化染色:8例EMA均阴性,8例Vimentin均阳性,6例CD34阳性,5例Bcl-2阳性,3例CD99阳性,8例STAT6均阳性。术后随访2~85个月,平均40.5月。术后未放疗的2例分别于术后3、60个月复发,并再次行手术切除;术后放疗的6例无复发。结论 脑膜血管周细胞瘤需与脑膜瘤鉴别,首选手术切除,术后放疗可以降低复发率。
Abstract:
【Abstract】 Objective To enhance the levels of diagnosis and treatment of meningeal hemangiopericytomas which is an uncommon disease. Methods The clinical data of 8 patients with meningeal hemangiopericytomases were analyzed retrospectively, including the clinical manifestations, imaging features and postoperative pathological data. Results The meningeal hemangiopericytomases were definitely diagnoses by the postoperative pathological examination but not by preoperative images examination. It was seen intraoperatively that the tumors appeared pale and the tumourous parenchyma was hard and tough. Of 8 patients with meningeal hemangiopericytomases, 7 received total resection of the tumors and 1 subtotal. Conclusion The differential diagnoses of the meningeal hemangiopericytomas and meninginoma should be made. The surgical resection followed by radiotherapy can reduce meningeal hemangiopericytomas recurrence.

参考文献/References:

[1] Joseph JT, Lisle DK, Jacoby LB, et al. NF2 gene analysis distinguishes hemangiopericytoma from meningioma [J]. Am J Pathol, 1995, 147: 1450-1455. [2] Chilosi M, Facchettti F, Dei Tos AP, et al. Bcl-2 expression in pleural and extrapleural solitary fibrous tumours [J]. J Pathol, 1997, 181: 362-367. [3] Westra WH, Gerald WL, Rosai J. Solitary fibrous tumor: consistent CD34 immunoreactivity and occurrence in the orbit [J]. Am J Surg Pathol, 1994, 18: 992-998. [4] Vogels RJ, VlenterieM, Versleijen-Jonkers YM, et al. Soli- tary fibrous tumor--clinicopathologic, immunohistochemi- cal and molecular analysis of 28 cases [J]. Diagn Pathol, 2014, 9: 224. [5] Koelsche C, Schweizer L, Renner M, et al. Nuclear reloca- tion of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour [J]. Histopathology, 2014, 65: 613-622. [6] Demicco EG, Harms PW, Patel RM, et al. Extensive survey of STAT6 expression in a large series of mesenchymal tumors [J]. Am J Clin Pathol, 2015, 143: 672-682. [7] Han Y, Zhang Q, Yu X, et al. Immunohistochemical detec- tion of STAT6, CD34, CD99 and BCL-2 for diagnosing solitary fibrous tumors/hemangiopericytomas [J]. Int J Clin Exp Pathol, 2015, 8: 13166-13175. [8] Fritchie KJ, Jin L, Rubin BP, et al. NAB2-STAT6 gene fusion in meningeal hemangiopericytoma and solitary fibrous tumor [J]. J Neuropathol Exp Neurol, 2016, 75: 263- 271. [9] Macagno N, Figarella-Branger D, Mokthari K, et al. Diffe- rential Diagnosis of Meningeal SFT-HPC and Meningioma: Which Immunohistochemical Markers Should Be Used [J]. Am J Surg Pathol, 2016, 40: 270-278. [10] Fusco MR, Salem MM, Gross BA, et al. Preoperative embo- lization of extra-axial hypervascular tumors with onyx [J]. J Cerebrovasc Endovasc Neurosurg, 2016, 18: 12-18. [11] Zhu H, Duran D, Hua L, et al. Prognostic factors in patients with primary hemangiopericytomas of the central nervous system: a series of 103 cases at a single institution [J]. World Neurosurg, 2016, 90: 414-419. [12] Lee EJ, Kim JH, Park ES, et al. The impact of postoperative radiation therapy on patterns of failure and survival impro- vement in patients with intracranial hemangiopericytoma [J]. J Neurooncol, 2016, 127: 181-190. [13] Kim YJ, Park JH, Kim YI, et al. Treatment strategy of intra- cranial hemangiopericytoma [J]. Brain Tumor Res Treat, 2015, 3: 68-74. [14] 彭 鹏,郭东生,王宝峰,等. 颅内脑膜血管周细胞瘤的诊 治分析[J]. 中国临床神经外科杂志,2013,12(18):714- 716.

相似文献/References:

[1]王振宇.脊髓髓内肿瘤诊断与治疗中若干问题的讨论[J].中国临床神经外科杂志,2015,(11):641.[doi:10.13798/j.issn.1009-153X.2015.11.001]
[2]王在贵 张新元 杨 铭 潘 力 李国栋 刘 征 伍 杰 马廉亭.MRI、320-CTA及DSA在脊髓血管病诊断中的应用[J].中国临床神经外科杂志,2015,(11):643.[doi:10.13798/j.issn.1009-153X.2015.11.002]
 WANG Zai-gui,ZHANG Xin-yuan,YANG Ming,et al.Value of MRI, 320-CTA and DSA to diagnosis of spinal vascular disease[J].,2015,(12):643.[doi:10.13798/j.issn.1009-153X.2015.11.002]
[3]于 涛 黄正通 王振宇.椎管内脊膜囊肿的临床特征和治疗方法[J].中国临床神经外科杂志,2015,(11):654.[doi:10.13798/j.issn.1009-153X.2015.11.005]
 YU Tao,HUANG Zheng-tong,WANG Zhen-yu.Clinical features and treatment of intraspinal arachnoid cysts[J].,2015,(12):654.[doi:10.13798/j.issn.1009-153X.2015.11.005]
[4]柳 羲 张 帆 田勤力 刘 利.成人幕上原始神经外胚层肿瘤3例报道及文献复习[J].中国临床神经外科杂志,2015,(11):689.[doi:10.13798/j.issn.1009-153X.2015.11.016]
[5]刘 阳 连 伟 综述 王任直 校审.垂体泌乳素腺瘤诊疗中常见问题及解决方案[J].中国临床神经外科杂志,2015,(11):698.[doi:10.13798/j.issn.1009-153X.2015.11.020]
[6]敖祥生 胡克琦.血管内治疗椎动脉夹层动脉瘤14例临床分析[J].中国临床神经外科杂志,2016,(05):302.[doi:10.13798/j.issn.1009-153X.2016.05.016]
[7]马廉亭.SDAVF与SPAVF的诊治与鉴别[J].中国临床神经外科杂志,2016,(07):385.[doi:10.13798/j.issn.1009-153X.2016.07.001]
[8]符传艺 陈健龙 张 茂 刘朝晖 黄垂学 黄 军 马建荣 赵建农.表现为脑室出血的颅内破裂动脉瘤的诊治[J].中国临床神经外科杂志,2016,(04):234.[doi:10.13798/j.issn.1009-153X.2016.04.014]
[9]周长帅 任志伟 综述 遇 涛 李勇杰 审校.岛叶癫痫症状学研究进展周长[J].中国临床神经外科杂志,2016,(04):249.[doi:10.13798/j.issn.1009-153X.2016.04.021]
[10]肖连福 黄瑞宏 陈昌勇.外伤性颅内静脉窦血栓形成1例[J].中国临床神经外科杂志,2016,(04):256.[doi:10.13798/j.issn.1009-153X.2016.04.024]

更新日期/Last Update: 2017-12-27