[1]王娇燕 孟凡华 刘魏然 魏春晓 林丽萍.SWI在胶质母细胞瘤与单发脑转移瘤鉴别中的价值[J].中国临床神经外科杂志,2018,(01):13-16.[doi:10.13798/j.issn.1009-153X.2018.01.005]
 WANG Jiao-yan,MENG Fan-hua,LIU Wei-ran,et al.Value of susceptibility-weighted imaging in differentiative diagnosis of glioblastomas and solitary brain metastases[J].,2018,(01):13-16.[doi:10.13798/j.issn.1009-153X.2018.01.005]
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SWI在胶质母细胞瘤与单发脑转移瘤鉴别中的价值()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年01期
页码:
13-16
栏目:
论著
出版日期:
2018-01-25

文章信息/Info

Title:
Value of susceptibility-weighted imaging in differentiative diagnosis of glioblastomas and solitary brain metastases
文章编号:
1009-153X(2018)01-0013-04
作者:
王娇燕 孟凡华 刘魏然 魏春晓 林丽萍
作者单位:200240 上海,复旦大学附属上海市第五人民医院放射科(王娇燕、孟凡华、刘魏然、魏春晓、林丽萍);200021 上海,上海中医药大学附属曙光医院放射科(王娇燕)
Author(s):
WANG Jiao-yan12 MENG Fan-hua1 LIU Wei-ran1 WEI Chun-xiao1 LIN Li-ping1.
1. Department of Diagnostic Radiology, The Fifth People’s Hospital, Fudan University, Shanghai 200240, China; 2. Department of Diagnostic Radiology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China
关键词:
胶质母细胞瘤脑转移瘤磁敏感加权成像鉴别诊断
Keywords:
Glioblastomas Brain metastases SWI MRI Differential diagnosis
分类号:
R 739.41; R 455.2
DOI:
10.13798/j.issn.1009-153X.2018.01.005
文献标志码:
A
摘要:
目的 探讨磁敏感加权成像(SWI)鉴别胶质母细胞瘤与单发脑转移瘤的临床价值。方法 回顾性分析2014年3月至2017年3月经病理证实的21例胶质母细胞瘤与21例脑转移瘤的影像学资料,比较两种肿瘤SWI指标,包括肿瘤内磁敏感信号(ITSS)评分、肿瘤静脉血管数目、出血个数及出血指数;采用受试者工作特征(ROC)曲线分析各指标鉴别诊断的效能。结果 两种肿瘤ITSS评分、出血个数无统计学差异(P>0.05);但是胶质母细胞瘤静脉血管数目明显高于脑转移瘤(P<0.05),出血指数明显低于脑转移瘤(P<0.05)。根据ROC曲线分析,肿瘤静脉血管数目为6.5时,鉴别诊断胶质母细胞瘤和脑转移瘤效能最高,曲线下面积为0.751,灵敏度、特异度分别为0.684、0.789;而出血指数为0.9时,鉴别诊断效能最高,曲线下面积为0.715,灵敏度、特异度分别为0.632、0.947。结论 采用SWI可为诊断脑肿瘤提供更多信息,对鉴别胶质母细胞瘤与脑转移瘤具有一定价值。
Abstract:
Objective To explore the optimal indicator and the corresponding diagnostic threshold to differentiate glioblastomas from solitary brain metastases using susceptibility-weighted imaging (SWI). Methods Four indicators of SWI including intratumorous susceptibility signal (ITSS) scores, the number of veins and the number of hemorrhage in the tumorous parenchyma and the bleeding index were derived from 21 patients with cerebral gliobastomas and 21 with solitary brain metastases confirmed pathologically who received routine MRI and SWI examination from March, 2014 to March, 2017. All the indicators were compared between the glioblastomas and solitary brain metastases, and then the receiver operating characteristic (ROC) curves were constructed to observe the efficiency of differential diagnosis. Results The number of the intratumorous veins was significantly more and the bleeding index were statistically lower in the glioblastomas than those in the metastases (P<0.01). There were insignificant differences in ITSS scores and the number of hemorrhage between the glioblastomas and metastases (P>0.05). The analyses of the number of the intratumorous veins and bleeding index by ROC curve showed that the area under the ROC curve of the number of the intratumorous veins was the highest (0.751) at the cut off value of 6.5, and the sensitivity and specificity were 0.684 and 0.789, respectively. The area under the ROC curve of the bleeding index was 0.715 at the cut off value of 0.9, and the sensitivity and specificity were 0.632 and 0.947 respectively. Conclusion SWI, which can provide the more information of tumors for the diagnosis is of value to differentiation of the glioblastomas from the solitary brain metastases.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:上海市第五人民医院青年基金(2016WYXG02) 通讯作者:林丽萍,E-mail:linlplucky@163.com
更新日期/Last Update: 2017-12-27