[1]李 宁 王寿龙 王 波 尚亚军 杨智勇 宋晓斌.脊髓终丝黏液乳头状室管膜瘤的显微手术治疗[J].中国临床神经外科杂志,2018,(06):407-409.[doi:10.13798/j.issn.1009-153X.2018.06.008]
 LI Ning,WANG Shou-long,WANG Bo,et al.Microsurgical treatment of myxopapillary ependymomas in the spinal cord terminal filaments[J].,2018,(06):407-409.[doi:10.13798/j.issn.1009-153X.2018.06.008]
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脊髓终丝黏液乳头状室管膜瘤的显微手术治疗()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年06期
页码:
407-409
栏目:
论著
出版日期:
2018-06-25

文章信息/Info

Title:
Microsurgical treatment of myxopapillary ependymomas in the spinal cord terminal filaments
文章编号:
1009-153X(2018)06-0407-03
作者:
李 宁 王寿龙 王 波 尚亚军 杨智勇 宋晓斌
作者单位:650000 昆明,昆明医科大学第一附属医院神经外科(李 宁、王寿龙、王 波、尚亚军、杨智勇、宋晓斌)
Author(s):
LI Ning WANG Shou-long WANG Bo SHANG Ya-jun YANG Zhi-yong SONG Xiao-bin.
Department of Neurosurgery, The First Affiliated Hospital, Kunming Medical University, Kunming 650032, China
关键词:
脊髓肿瘤黏液乳头状室管膜瘤脊髓终丝显微手术
Keywords:
Myxopapillary ependymoma Spinal cord Terminal filament Microsurgical treatment
分类号:
R 739.42; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2018.06.008
文献标志码:
A
摘要:
目的 探讨脊髓终丝黏液乳头状室管膜瘤(MPE)的手术方法及疗效。方法 回顾性分析显微手术治疗的16例脊髓终丝MPE的临床资料。结果 16例肿瘤均全切除。出院时临床症状全部得到明显改善。16例随访10~70个月,平均45个月,未见复发,未出现脊髓栓系综合征和脊柱畸形;McCormick脊髓功能评分均达到Ⅰ级。结论 显微手术是脊髓终丝MPE的有效治疗方法。
Abstract:
Objective To analyze the clinical characteristics and microsurgical treatment principles of the myxopapillary ependymomas in the spinal cord terminal filaments. Methods The clinical data of 16 patients with spinal cord terminal filaments myxopapillary ependymomas who underwent surgery from January, 2010 to January, 2018 were analyzed retrospectively, including the clinical manifestations, diagnosis and treatment. Results The first symptom was numbness or weakness in the lower extremities in 8 patients, pain in 1 and fecal and urinary incontinence in 4. The ependymomas were found out on physical examination in 3 patients. Preoperative McCormick spinal cord function score was grade Ⅰ in 11 patients and grade Ⅱ in 5. Preoperative MRI showed that the tumors were in the lumbar spines in 13 patients and in the lumbosacral spines in 3. The Tumors were totally removed in all the patients. Symptoms were significantly improved on discharge from hospital in all the patients. The recurrence of the tumors, tethered cord syndrome and spinal deformity were not observed in all the patients during following-up from 10 to 70 months. Conclusions Microsurgical removal of the lesion should be selected first in the patients with myxopapillary ependymoma in the spinal cord terminal filaments, in whom the prognoses are mainly affected by degree of preoperative neurological deficits and surgical methods.

参考文献/References:

[1] Masashi U, Jun T, Keijiro, M, et al. Myxopapillary ependy- moma of the cauda equina in a 5-year-old boy [J]. Asian Spine, 2014, 8(6): 846-851.
[2] Aghakhani N, David P, Parker F, et al. Intramedullary spinal ependymomas: analysis of a consecutive series of 82 adult cases with particular attention to patients with no preopera- tive neurological deficit [J]. Neurosurgery, 2008, 62: 1279- 1286.
[3] Kucia EJ, Bambakidis NC, Chang SW, et al. Surgical tech- nique and outcomes in the treatment of spinal cord epen- dymomas, part 1: intramedullary ependymomas [J]. Neuro- surgery, 2011, 68(1 Suppl Operative): 57-63.
[4] 杨蕊梦,江新青. 马尾和终丝部黏液乳头状室管膜瘤的 MR征象分析[J]. 放射学实践,2011,12:3.
[5] Matthew K, Tobin BS, Joseph R. Intramedullary spinal cord tumors: a review of current and future treatment strategies [J]. Neurosurg Focus, 2015, 39(2): E14.
[6] 朱司阳,魏祥品,牛朝诗,等. 神经电生理监测下显微手术 切除脊髓髓内病变[J]. 中国临床神经外科杂志,2012, 17(11):674-676.
[7] Lee SH, Chung CK, Kim CH, et al. Long term outcomes of surgical resection with or without adjuvant radiation therapy for treatment of spinal ependymoma: a retrospective multi- center study by the Korea Spinal Oncology Research Group [J]. Neuro Oncol, 2013, 15: 921-929.
[8] Harrop JS, Ganju A, Groff M, et al. Primary intramedullary tumors of thespinal cord [J]. Spine, 2009, 34(22 Suppl): 69- 77.
[9] 孙 鹏,范多娇,范 涛,等. 原发性脊髓胶质瘤的综合治 疗现状[J]. 中国医师进修杂志,2013,36:72-74.
[10] Eroes CA, Zausinger S, Kreth FW, et al. Intramedullary low grade astrocytoma andependymoma: surgical results and predicting factors for clinical outcome [J]. Acta Neurochir (Wien), 2010, 152: 611-618.
[11] Ramaswamy V, Hielscher T, Mack SC, et al. Therapeutic impact of cytoreductive surgery and irradition of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis [J]. Clin Oncol, 2016, 34: 2468-2477.
[12] 陈 晟,刘从国,徐昌林,等. 显微外科手术联合术后放疗 治疗脊髓髓内胶质瘤的临床疗效[J]. 中国中国肿瘤临床 与康复,2016,23(6):708-710.
[13] 储卫华,叶信珍. 脊髓髓内室管膜瘤的临床特点与显微手 术治疗[J]. 中国现代神经疾病杂志, 2013,13(12):1000- 1005.

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备注/Memo

备注/Memo:
通讯作者:宋晓斌,E-mail:sxb8@sina.com
更新日期/Last Update: 2018-06-25