[1]徐 阳 刘宝辉 袁凡恩 刘骏辉 许鹏飞 陈谦学.小胶质细胞在缺血性脑卒中中作用机制的研究进展[J].中国临床神经外科杂志,2018,(07):503-505.[doi:10.13798/j.issn.1009-153X.2018.07.020]
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小胶质细胞在缺血性脑卒中中作用机制的研究进展()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年07期
页码:
503-505
栏目:
论著
出版日期:
2018-07-25

文章信息/Info

文章编号:
1009-153X(2018)07-0503-03
作者:
徐 阳 刘宝辉 袁凡恩 刘骏辉 许鹏飞 陈谦学
作者单位:430060 武汉,武汉大学人民医院神经外科
关键词:
缺血性脑卒中小胶质细胞活化极化炎症反应
分类号:
R 743.3
DOI:
10.13798/j.issn.1009-153X.2018.07.020
文献标志码:
B

参考文献/References:

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[2] Fagan SC, Hess DC, Hohnadel EJ, et al. Targets for vascular protection after acute ischemic stroke [J]. Stroke, 2004, 35: 2220-2225.
[3] Jin R, Yang G, Li G. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells [J]. J Leukoc Biol, 2010, 87: 779-789.
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[5] Gliem M, Mausberg AK, Lee JI, et al. Macrophages prevent hemorrhagic infarct transformation in murine stroke models [J]. Ann Neurol, 2012, 71: 743-752.
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[7] Kierdorf K, Erny D, Goldmann T, et al. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8- dependent pathways [J]. Nat Neurosci, 2013, 16: 273-280.
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[10] Gelderblom M, Leypoldt F, Steinbach K, et al. Temporal and spatial dynamics of cerebral immune cell accumulation in stroke [J]. Stroke, 2009, 40: 1849-1857.
[11] da Fonseca AC, Matias D, Garcia C, et al. The impact of microglial activation on blood-brain barrier in brain diseases [J]. Front Cell Neurosci, 2014, 8:1-13.
[12] Kacimi R, Giffard RG, Yenari MA. Endotoxin-activated microglia injure brain derived endothelial cells via NF- kappaB, JAK-STAT and JNK stress kinase pathways [J]. J Inflamm (Lond), 2011, 8: 7-22.
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[14] Kanazawa M, Kawamura K, Takahashi T, et al. Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke [J]. Brain, 2015, 138(7): 1932-1948.
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[17] Szalay G, Martinecz B, Lenart N, et al. Microglia protect against brain injury and their selective elimination dysregu- lates neuronal network activity after stroke[J]. Nat Commun, 2016, 7: 11499-11514.
[18] Lalancette-Hebert M, Gowing G, Simard A, et al. Selective ablation of proliferating microglial cells exacerbates ische mic injury in the brain [J]. J Neurosci, 2007, 27(10): 2596- 2605.
[19] Hu X, Leak RK, Shi Y, et al. Microglial and macrophage polarization-new prospects for brain repair [J]. Nat Rev Neurol, 2015, 11(1): 56-64.
[20] Chhor V, Le Charpentier, T, Lebon, S, et al. Characteriza- tion of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro [J]. Brain Behav Immun, 2013, 32(100): 70-85.
[21] Perego C, Fumagalli S, De Simoni MG. Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice [J]. J. Neuroinflammation, 2011, 8(1): 174-184.
[22] Hu X, Li P, Guo Y, et al. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia [J]. Stroke, 2012, 43: 3063-3070.
[23] Jimenez S, Baglietto Vargas D, Caballero C, et al. Inflamma- tory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic [J]. J Neurosci, 2008, 28(45): 11650-11661.
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备注/Memo

备注/Memo:
通讯作者:陈谦学,E-mail:chenqx666@whu.edu.cn
更新日期/Last Update: 2018-07-25