[1]韩冰莎 李 娇 李 翔 栗艳茹 张 磊 赵敬河 冯 光.脑氧饱和度监测目标导向治疗在前循环急性缺血性脑卒中机械取栓术后管理的效果[J].中国临床神经外科杂志,2020,(02):73-75.[doi:10.13798/j.issn.1009-153X.2020.02.004]
 HAN Bing-sha,LI Jiao,LI Xiang,et al.Effects of targeted therapy under direction of monitoring cerebral oxygen saturation on patients with acute ischemic stroke of anterior circulation undergoing mechanical thrombectomy[J].,2020,(02):73-75.[doi:10.13798/j.issn.1009-153X.2020.02.004]
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脑氧饱和度监测目标导向治疗在前循环急性缺血性脑卒中机械取栓术后管理的效果()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2020年02期
页码:
73-75
栏目:
论著
出版日期:
2020-02-25

文章信息/Info

Title:
Effects of targeted therapy under direction of monitoring cerebral oxygen saturation on patients with acute ischemic stroke of anterior circulation undergoing mechanical thrombectomy
文章编号:
1009-153X(2020)02-0073-03
作者:
韩冰莎 李 娇 李 翔 栗艳茹 张 磊 赵敬河 冯 光
450003郑州,河南省人民医院(郑州大学人民医院)神经外科(韩冰莎、李 娇、李 翔、栗艳茹、张 磊、赵敬河、冯 光)
Author(s):
HAN Bing-sha LI Jiao LI Xiang LI Yan-ru ZHANG Lei ZHAO Jing-he FENG Guang.
Department of Neurosurgery, He'nan Provincial People's Hospital (Zhengzhou University People's Hospital), Zhengzhou 450003, China
关键词:
急性缺血性脑卒中颅内前循环局部脑氧饱和度机械取栓术
Keywords:
Acute ischemic stroke Anterior circulation Regional cerebral oxygen saturation Mechanical thrombectomy
分类号:
R 743.3; R 815.2
DOI:
10.13798/j.issn.1009-153X.2020.02.004
文献标志码:
A
摘要:
目的 探讨局部脑氧饱和度(rScO2)监测目标导向治疗在前循环急性缺血性卒中(AIS)机械取栓术后的临床价值。方法 前瞻性收集2017年4月至2019年4月河南省人民医院神经外科ICU行机械取栓术治疗的前循环AIS 142例,采用随机数字表法分为观察组和对照组,各71例。对照组实施常规神经重症监护治疗,观察组在对照组基础上予以rScO2目标导向治疗。结果 观察组出院时NIHSS评分与对照组无统计学差异(P>0.05),但是ICU住院时间较对照组明显缩短(P<0.05)。术后6个月,观察组mRS评分及GOS-E评分均明显优于对照组(P<0.05),脑出血转化、脑血管再闭塞等发生率及病死率均明显低于对照组(P<0.05)。术后6个月,Kaplan-Meier生存曲线分析显示观察组生存时间明显优于对照组(P<0.05)。结论 rScO2监测目标导向治疗能有效缩短前循环AIS机械取栓术的住院时间,降低并发症发生率和病死率,改善病人预后。
Abstract:
Objective To evaluate the clinical effects of targeted therapy under direction of monitoring regional cerebral oxygen saturation (rScO2) on the patients with acute ischemic stroke (AIS) of anterior circulation undergoing mechanical thrombectomy. Methods Of 142 patients with AIS of anterior circulation, who underwent mechanical thrombectomy in Intensive Care Unit (ICU) of Department of Neurosurgery of Henan Provincial People's Hospital from April, 2017 to April, 2019, 71 ( control group) received routine neurological intensive care and treatment and 71 (observed group) received targeted therapy under the direction of monitoring rScO2 . The treatment outcomes were analyzed and compared between the groups. Results The ICU hospital stay, rates of occurrence of cerebral hemorrhage, recurrence of cerebral ischemia and death within 6 months after the treatment were significantly lower in the observed group than those in the control group (P<0.05). The prognoses were significantly better in the observed group than those in the control group according to modified Rankin scale and GOS 6 months after the treatment (P<0.05). The survival curve showed that the survival time was significantly longer in the observed group than that in the control group (P<0.05). Conclusion The targeted therapy under the direction of monitoring rScO2 is very helpful to the decrease in the hospital stay and improvement of the prognosis in the patients with anterior circulation AIS undergoing mechanical thrombectomy.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:河南省医学科技攻关项目计划(SBGJ2018063) 通讯作者:冯 光,E-mail:fgwxh@163.com(2019-11-15收稿,2019-12-19修回)
更新日期/Last Update: 2020-02-25