[1]黄雨达,曹航,王凝瑞,等.磁共振弥散成像技术在难治性癫痫手术治疗中的应用[J].中国临床神经外科杂志,2024,29(09):556-560.[doi:10.13798/j.issn.1009-153X.2024.09.011]
　HUANG Yu-da,CAO Hang,WANG Ning-rui,et al.Application of magnetic resonance diffusion imaging in the surgical management for drug-resistant epilepsy[J].,2024,29(09):556-560.[doi:10.13798/j.issn.1009-153X.2024.09.011]
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磁共振弥散成像技术在难治性癫痫手术治疗中的应用()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
29
期数:
2024年09期
页码:
556-560
栏目:
综述
出版日期:
2024-09-30

文章信息/Info

Title:
Application of magnetic resonance diffusion imaging in the surgical management for drug-resistant epilepsy
文章编号:
1009-153X（2024）09-0556-05
作者:
黄雨达; 曹航; 王凝瑞; 魏鹏虎; 单永治; 赵国光
100053 北京，首都医科大学宣武医院神经外科/首都医科大学癫痫临床诊疗与研究中心（黄雨达、曹　航、王凝瑞、魏鹏虎、单永治、赵国光）750000 银川，宁夏医科大学公共卫生学院流行病学教研室（王凝瑞）
Author(s):
HUANG Yu-da1;  CAO Hang1;  WANG Ning-rui1; 2;  WEI Peng-hu1;  SHAN Yong-zhi;  ZHAO Guo-guang1
1. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University & Epilepsy Clinical Diagnosis and Treatment Research Center, Capital Medical University, Beijing 100053, China; 2. Department of Epidemiology, School of Public Health, Ningxia Medical University, Yinchuan 750000, China
关键词:
药物难治性癫痫; 手术治疗; 磁共振弥散成像技术; 术前诊断; 术中保护; 术后评估
Keywords:
Drug-resistant epilepsy;  Surgical treatment;  magnetic resonance diffusion imaging;  Preoperative diagnosis;  Intraoperative protection;  Postoperative evaluation
分类号:
R 742.1; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2024.09.011
文献标志码:
A
摘要:
癫痫是一种由局部神经元异常放电并通过网络传导引起的中枢神经系统功能障碍性疾病，其中约1/3的病人服用两种或两种以上抗癫痫药物治疗难以控制癫痫发作，称药物难治性癫痫。手术切除致痫灶是治疗药物难治性癫痫的有效手段。因难治性癫痫的发病机制复杂，临床表现形式多样，手术治疗面临诸多问题，例如术前病因学诊断不准确、术中易损伤功能区、术后预后评估不理想等。近年来，磁共振弥散成像技术不断进步，其在分析白质结构改变、脑结构网络等方面具有独特优势，在药物难治性癫痫的术前病因学诊断、术中功能区保护和术后预后评估中发挥着日益重要的作用。本文综磁共振述弥散成像技术在药物难治性癫痫手术治疗中的应用进展，以期为临床提供帮助。
Abstract:
Epilepsy is a disorder of the central nervous system resulting from abnormal electrical discharges of local neurons and their propagation through neural networks. Approximately one-third of patients with epilepsy fail to control seizures despite taking two or more antiepileptic drugs, which is known as drug-resistant epilepsy (DRE). Surgical resection of the epileptogenic focus is an effective approach for treating DRE. However, due to the complex pathogenesis and diverse clinical manifestations of DRE, surgical treatment encounters numerous challenges, such as inaccurate preoperative etiological diagnosis, potential damage to functional areas during surgery, and suboptimal postoperative prognosis assessment. In recent years, magnetic resonance diffusion imaging has been constantly evolving and possesses unique advantages in analyzing white matter structure alterations and brain structural networks. It plays an increasingly crucial role in preoperative etiological diagnosis, intraoperative protection of functional areas, and postoperative prognosis evaluation for DRE surgery. This article reviews the application advancements of magnetic resonance diffusion imaging in the surgical treatment of DRE, with the expectation of providing clinical assistance.

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备注/Memo

备注/Memo:
（2022-07-18收稿，2024-02-16）
通信作者：赵国光，Email：ggzhao@vip.sina.com
更新日期/Last Update: 2024-09-30