[1]于贝贝　荆林凯　王　劲等.脊髓毛细胞型星形细胞瘤的诊断与治疗[J].中国临床神经外科杂志,2021,26(03):153-155.[doi:10.13798/j.issn.1009-153X.2021.03.003]
　YU Bei-bei,JING Lin-kai,WANG Bo,et al.Diagnosis and treatment of spinal cord pilocytic astrocytoma (report of 12 cases)[J].,2021,26(03):153-155.[doi:10.13798/j.issn.1009-153X.2021.03.003]
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脊髓毛细胞型星形细胞瘤的诊断与治疗()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
26
期数:
2021年03期
页码:
153-155
栏目:
论著
出版日期:
2021-03-25

文章信息/Info

Title:
Diagnosis and treatment of spinal cord pilocytic astrocytoma (report of 12 cases)
文章编号:
1009-153X（2021）03-0153-03
作者:
于贝贝　荆林凯　王　劲等
102218 北京，清华大学附属北京清华长庚医院神经外科（于贝贝、荆林凯、王　劲、王贵怀）
Author(s):
YU Bei-bei;  JING Lin-kai;  WANG Bo;  et al
Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, Beijing 102218, China
关键词:
脊髓肿瘤; 毛细胞型星形细胞瘤; 显微手术
Keywords:
Spinal cord tumor;  Pilocytic astrocytoma;  Microsurgery
分类号:
R 739.42; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2021.03.003
文献标志码:
A
摘要:
目的 总结脊髓毛细胞型星形细胞瘤（PA）的诊治经验。方法 回顾性分析2015年1月至2020年1月显微手术切除的12例脊髓PA的临床资料，结合文献总结诊治经验。结果 肿瘤全切除8例，大部分切除4例。术后病理证实均为脊髓PA（WHO分级Ⅰ级）。术后随访6~54个月，平均（29.3±16.1）个月。末次随访，5例脊髓功能较术前改善，7例无变化。随访观察期间未见复发及播散。结论 脊髓PA临床特征及影像学特征不典型，确诊依靠病理学检查。在保护神经功能的前提下，全切除/近全切除肿瘤是获得良好预后的关键。
Abstract:
Objective To summarize the experience in treating spinal cord pilocytic astrocytomas (PA). Methods The clinical dat of 12 patients with spinal cord PA who underwent surgery from January 2015 to January 2020 were analyzed retrospectively, and the related literatures were reviewed. Results Total resection of tumors was achieved in 8 patients and great partial in 4. Postoperative pathological examination showed spinal cord PA (WHO grade Ⅰ) in all the patients. The follow-up (range, 6~54 months; mean, 29.3±16.1 months) results showed improvement of spinal cord function in 5 patients and no change in 7 at the last follow-up. There was no tumor recurrence or tumor spread during the follow-up. Conclusions The clinical features and imaging features of spinal cord PA are atypical. Difinite diagnosis of spinal cord PA mainly depends on the pathological examination. Total resection/subtotal total resection of the tumor is the key to obtain good prognoses in the patients with spinal cord PA.

参考文献/References:

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[8] Rodriguez FJ, Brosnan-Cashman JA, Allen SJ, et al. Alter-native lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia [J]. Brain Pathol, 2019, 29(1): 126-140.
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备注/Memo

备注/Memo:
通讯作者：王贵怀，E-mail：guihuai_wang@163.com
更新日期/Last Update: 2021-03-25