[1]王　涛　徐国政　许　川　祝友红　杨　媛.伽玛刀治疗海绵窦区海绵状血管瘤术后残留的疗效观察[J].中国临床神经外科杂志,2015,(04):211-213.[doi:10.13798/j.issn.1009-153X.2015.04.006]
　WANG Tao,XU Guo-zheng,XU Chuan,et al.Curative effect of gamma knife on postoperative residues of cavernous sinuses cavernous hemangiomas[J].,2015,(04):211-213.[doi:10.13798/j.issn.1009-153X.2015.04.006]
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伽玛刀治疗海绵窦区海绵状血管瘤术后残留的疗效观察()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年04期
页码:
211-213
栏目:
论著
出版日期:
2015-04-30

文章信息/Info

Title:
Curative effect of gamma knife on postoperative residues of cavernous sinuses cavernous hemangiomas
文章编号:
1009-153X（2015）04-0211-03
作者:
王　涛　徐国政　许　川　祝友红　杨　媛
430070 武汉，广州军区武汉总医院神经外科（王　涛、徐国政、许　川、祝友红、杨　媛）
Author(s):
WANG Tao;  XU Guo-zheng;  XU Chuan;  ZHU You-hong;  YANG Yuan.
Department of Neurosurgery, Wuhan General Hospital, Guangzhou Command, PLA, Wuhan 430070, China
关键词:
海绵窦区海绵状血管瘤; 术后残留; 伽玛刀; 疗效
Keywords:
Cavernous sinus;  Cavernous hemangiomas;  Postoperative residue;  Gamma knife
分类号:
R739.41;R815.5
DOI:
10.13798/j.issn.1009-153X.2015.04.006
文献标志码:
A
摘要:
目的 观察伽玛刀治疗海绵窦区海绵状血管瘤（CHCS）术后残留的疗效。方法回顾性分析6例经开颅手术后病理学确诊的CHCS术后残留患者的临床资料；均行伽马刀治疗，2例肿瘤最大径超过3.5 cm者行伽玛刀体积分割治疗；肿瘤周边剂量10~13 Gy,平均11.50 Gy；肿瘤中心剂量22~26 Gy,平均23.28 Gy。随访23~101个月，平均44.0月。结果 肿瘤基本消失2例，明显缩小2例，无变化1例，有效率为100%。患者均未出现新的颅神经受损症状。结论 伽玛刀对CHCS术后残留比较敏感，较低剂量即可控制其生长，疗效良好，且对体积较大的CHCS术后残留也可采用伽玛刀体积或剂量分割的方法就能获得良好的疗效。
Abstract:
Objective To observe the curative effect of gamma knife on the postoperative residues of the cavernous sinus cavernous hemangiomas (CSCHs). Methods Of 6 patients with CSCHs who underwent microsurgery, 2 were males and 4 were females. The diagnosis of CSCHs was definitely made by pathological examination in all the patients treated by gamma knife. The diameters of postoperative residues of CSCHs ranged from 2.3 to 5.9 cm (mean, 3.5 cm). The radiant doses of the tumorous margins ranged from 10 to 13 Gy (mean, 11.50 Gy). The radiant doses of the tumorous centers ranged from 22 to 26 Gy (mean, 23.28 Gy). All the patients were followed up from 23 to 101 months (mean, 44.0 months). Results Of 6 postoperative residues of CSCHs, 2 basically disappeared, 3 significantly shrank and 1 was unchanged after the treatment with gamma knife. The new damage to the cranial nerves after the gamma knife radiosurgery did not occurred in all the patients. Conclusion The curative effect of gamma knife on the postoperative residues of CSCHs is good.

参考文献/References:

[1] 李　龄. 听神经瘤[M]. 北京：人民卫生出版社，2002. 124- 126.
[2] 周　椿，陈广鑫，沈光建，等. 伽玛刀治疗颅底脑膜瘤的长 期疗效分析[J]. 中国临床神经外科杂志，2011，16：117- 118.
[3] 孙时斌，刘阿力，王忠诚，等. 三叉神经鞘瘤的伽玛刀治疗 [J]. 中华神经外科杂志，2006，22：275-278.
[4] 方应洪，韩金安，岳　培，等. 立体定向活检术结合伽玛刀 治疗脑深部胶质瘤[J]. 中国临床神经外科杂志，2014， 19：346-347，350.
[5] Hori S, Hayashi N, Nomoto K, et al. Cavernous sinus caver- nous hemangioma largely extending into the sella tureica and mimicking pituitary adenoma [J]. Neurol Med Chir (Tokyo), 2010, 50: 330-332.
[6] Fraser JF, Mass AY, Brown S, et al. Transnasal endoscopic reseetion of a cavernous sinus hemangioma: technical note and review of the literature [J]. Skull Base, 2008, 18: 309- 315.
[7] 伍犹梁，梁军湘，刘德平，等. 海绵窦海绵状血管瘤的影像 学特点及伽玛刀治疗[J]. 中华神经外科杂志，2011，27 （10）：996-999.
[8] Zhou LF, Mao Y, Chen L. Diagnosis and surgical treatment of cavernous sinus hemangiomas: an experience of 20 cases [J]. Surg Neurol, 2003, 60: 31-38.
[9] 于兰冰，赵继宗，贾文清. 海绵窦海绵状血管瘤的诊断及 治疗[J]. 中华医学杂志，2004，84：2086-2088.
[10] 刘伟国，叶红星，沈　宏，等. 海绵窦海绵状血管瘤的诊断 和显微手术治疗[J]. 中华神经外科杂志，2005，21：354- 356.
[11] 罗世祺，马振宇，谢　坚，等. 中颅窝脑外海绵状血管瘤 [J]. 中华神经外科杂志，1993，9：318-320.
[12] 吴立权，刘仁忠，陈谦学，等. 海绵窦区海绵状血管瘤的 临床特征及显微外科治疗[J]. 中国临床神经外科杂志， 2011，16：117-118.
[13] Wang X, Mei GLiu X, Dai J, et al. The role of stereotactic radiosurgery in cavernous sinus hemangiomas: a systematic review and meta-analysis [J]. J Neurooncol, 2012, 107(2): 239-245.
[14] 王恩敏，潘　力，王滨江，等. 海绵窦海绵状血管瘤的MRI 表现及伽玛刀治疗[J]. 中华神经外科杂志，2006，22（5）： 267-270.
[15] Bansal S, Suri A, Singh M. Cavernous sinus hemangioma: a fourteen year single institution experience [J]. J Clin Neuro- scie, 2014, 21: 968-974.
[16] Song SW, Kim DG, Chung HT, et al. Stereotactic radiosur- gery for cavernous sinus hemangiomas [J]. J Neurooncol, 2014, 118: 163-168.

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更新日期/Last Update: 2016-04-25