[1]曹付强　扶　宇　王本瀚　姚安会　唐　斌　刘　伟　谢　爽　李经纶.DTI及重建技术在重型颅脑损伤预后评估中的作用[J].中国临床神经外科杂志,2020,(10):674-676.[doi:10.13798/j.issn.1009-153X.2020.10.005]
　CAO Fu-qiang,FU Yu,WANG Ben-han,et al.Value of DTI and its reconstruction techniques in prognosis evaluation of patients with severe traumatic brain injury[J].,2020,(10):674-676.[doi:10.13798/j.issn.1009-153X.2020.10.005]
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DTI及重建技术在重型颅脑损伤预后评估中的作用()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2020年10期
页码:
674-676
栏目:
论著
出版日期:
2020-10-25

文章信息/Info

Title:
Value of DTI and its reconstruction techniques in prognosis evaluation of patients with severe traumatic brain injury
文章编号:
1009-153X（2020）10-0674-03
作者:
曹付强　扶　宇　王本瀚　姚安会　唐　斌　刘　伟　谢　爽　李经纶
450042 郑州，中国人民解放军联勤保障部队第988医院神经外科（曹付强、扶　宇、王本瀚、姚安会、唐　斌、刘　伟、谢　爽、李经纶）
Author(s):
CAO Fu-qiang;  FU Yu;  WANG Ben-han;  YAO An-hui;  TANG Bin;  LIU Wei;  XIE Shuang;  LI Jing-lun.
Department of Neurosurgery, The 988th Hospital of the Joint Logistics Support Force, PLA, Zhengzhou 450042, China
关键词:
重型颅脑损伤; 纤维束示踪技术; 弥散张量成像; 预后评估
Keywords:
Severe traumatic brain injury;  Diffusion tensor imaging;  Diffusion tensor imaging;  Prognosis evaluation
分类号:
R 651.1+5; R 445.2
DOI:
10.13798/j.issn.1009-153X.2020.10.005
文献标志码:
A
摘要:
目的 通过磁共振弥散张量成像（DTI）以及弥散张量纤维束成像（DTT）分析中脑平面纤维束形态及可观测纤维束数量变化，预测重型颅脑损伤病人预后，为临床工作提供参考。方法 选择13例重型颅脑损伤，入院后予以磁共振平扫及DTI扫描，间隔1~3周后再次复查；对中脑平面纤维束进行重建并进行统计分析。结果 13例出院后随访3个月~2年；11例GCS评分恢复较好，2例长期昏迷。11例恢复较好病人，入院时纤维束形态无法追踪、稀疏，随访时均有恢复；GCS评分越高，纤维束形态越饱满、无明显缺失；末次随访时纤维束量明显升高（P<0.05）。2例长期昏迷病人纤维束形态随访期间与入院时相比无明显变化；可观测纤维束数量无明显变化，甚至有所下降。结论 DTI及重建技术可以用于重型颅脑损伤预后的评估，可观测纤维束数量，量化分析病人恢复情况，对临床有指导意义。
Abstract:
Objective To detect the changes in the fiber bundle morphology and the number of observable fiber bundles in the midbrain of patients with severe traumatic brain injury (TBI) by the diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) in order to assess the significance of DTI and its reconstruction techniques for the prognosis evaluation of patients. Methods The MRI and DTI were performed on 13 patients with severe TBI after admission, and re-examinations were performed 1~3 weeks later. The fiber tracts in the midbrain were reconstructed and statistically analyzed. Results The follow-up of 13 patients ranged from 3 months to 2 years. Eleven patients had good recovery of GCS score, and 2 were in long-term coma during the follw-up. Of 11 patients with good recovery, the morphology of the fiber bundles could not be tracked and sparse upon at admission, and all recovered during the follow-up; the higher of the GCS score, the fuller the fiber bundle morphology without obvious loss; the amount of fiber bundles was significantly increased at the last follow-up (P<0.05). Of 2 patients with long-term coma, the fiber bundle morphology had no significant change during the follow-up, and the number of observable fiber bundles did not change significantly (P>0.05). Conclusions DTI and its reconstruction techniques can be used to evaluate the prognosis of patients with severe TBI, and the statistics of the number of observable fiber bundles can be used as an indicator for quantitative analysis of the recovery of patients, which has guiding significance for clinical practice.

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备注/Memo

备注/Memo:
2020-06-27收稿，2020-08-03修回
基金项目：中国人民解放军联勤保障部队面上项目（CJN16J004）；河南省医学科技攻关计划联合共建项目（LHGJ20190871）
通讯作者：李经纶，E-mail:ljl548@163.com
更新日期/Last Update: 2020-10-20