[1]吴 明 余任喜 吕胜青 李 佳.脑功能区病变术后早期认知功能变化的影响因素分析[J].中国临床神经外科杂志,2015,(04):217-218221.[doi:10.13798/j.issn.1009-153X.2015.04.008]
 WU Ming,YU Ren-xi,Lü Shen-qing,et al.Analysis of factors related to changes in cognitive function early after surgery in patients with cerebral function area lesions[J].,2015,(04):217-218221.[doi:10.13798/j.issn.1009-153X.2015.04.008]
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脑功能区病变术后早期认知功能变化的影响因素分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年04期
页码:
217-218221
栏目:
论著
出版日期:
2015-04-30

文章信息/Info

Title:
Analysis of factors related to changes in cognitive function early after surgery in patients with cerebral function area lesions
文章编号:
1009-153X(2015)04-0217-02
作者:
吴 明 余任喜 吕胜青 李 佳
332000 江西九江,解放军第171医院神经外科(吴 明、余任喜、李 佳);
400037 重庆,第三军医大学新桥医院神经外科(吕胜青)
Author(s):
WU Ming1 YU Ren-xi1 Lü Shen-qing2 LI Jia1.
1. Department of Neurosurgery, The 171st Hospital, PLA, Jiujiang 332000, China;
2. Department of Neurosurgery, Xinqiao Hospital, The Third Millitary Medical University, Chongqing 400037, China
关键词:
脑功能区病变认知功能影响因素唤醒麻醉手术
Keywords:
Cerebral function Lesions area Cognitive function Surgery Risk factor
分类号:
R651.1+1
DOI:
10.13798/j.issn.1009-153X.2015.04.008
文献标志码:
A
摘要:
目的 探讨脑功能区病变患者术后早期认知功能变化的影响因素。方法 回顾性分析86例行唤醒麻醉手术治疗的脑功能区病变患者的临床资料。使用中国修订韦氏成人智力量表评估患者手术前后认知功能。采用多因素logistic回归分析患者术后早期认知功能的影响因素。结果 41例(47.7%)患者术后早期认知功能比术前明显下降(P<0.05)。多因素logistic回归分析,结果显示病灶侧别、病灶大小、病理学性质、切除程度、病变与功能区边界距离是患者术后认知功能下降独立危险因素。>结论 病变位于优势半球、手术切除程度高、病变与功能区边界距离近、病变恶性程度高以及病变体积大是脑功能区病变患者术后早期认知功能下降的危险因素。
Abstract:
Objective To explore the factors influencing cognitive function early after surgery in the patients with cerebral function area lesions. Methods The verbal intelligence quotient (VIQ), operating intelligence quotient (PIQ), full intelligence quotient (FIQ) were determined by China revised Wechsler Adult Intelligence Scale (WAIS-RC) before surgery and 7~10 days after wake-up surgery in 86 patients with cerebral function area lesions. The possible factors influencing the cognitive function after the surgery including the gender, age, cultural level, lesion hemisphere, lesion location, lesion size, lesion pathology characteristics, distance between the lesions and border of cerebral function area, extent of surgical resection of the lesion were analyzed by the univariate and multivariate logistic regression analysis in all the patients. Results VIQ, PIQ and FIQ were significantly lower after the surgery than those before the surgery in the patients with cerebral function area lesions (P<0.05). the="" multivariate="" logistic="" regression="" analysis="" showed="" that="" lesion="" size,="" hemisphere,="" distance="" between="" lesions="" and="" border="" of="" cerebral="" function="" area,="" pathological="" characteristics="" lesions,="" extent="" surgical="" resection="" were="" significantly="" related="" to="" changes="" in="" cognitive="" early="" after="" wake-up="" surgery="" patients="" with="" area="" (P<0.05).>Conclusions The lesions in the dominant hemisphere, a high extent of surgical resection of the lesion, near distance between the lesion and cerebral function area, highly malignant lesion and large volume lesion were the risk factor of the decline in cognitive function early after the wake-up surgery in the patients with cerebral function area lesions. The lesion in the cerebral function area should be totally resected as possible under the prerequisite of the protection of neurological function as possible.

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更新日期/Last Update: 2016-04-25