[1]解利平、林 涛、束 坤、冯 磊、苏 龙、车海江、王 鹏.内镜下经鼻蝶入路视神经管减压术治疗外伤性视神经病手术时机的Meta分析[J].中国临床神经外科杂志,2017,(11):761-763794.[doi:10.13798/j.issn.1009-153X.2017.11.009]
 XIE Li-ping,LIN Tao,SHU Kun,et al.Meta-analysis of opportunity of endoscopic endonasal optic canal decompression in patients with traumatic optic neuropathy[J].,2017,(11):761-763794.[doi:10.13798/j.issn.1009-153X.2017.11.009]
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内镜下经鼻蝶入路视神经管减压术治疗外伤性视神经病手术时机的Meta分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年11期
页码:
761-763794
栏目:
论著
出版日期:
2017-11-25

文章信息/Info

Title:
Meta-analysis of opportunity of endoscopic endonasal optic canal decompression in patients with traumatic optic neuropathy
文章编号:
1009-153X(2017)11-0761-03
作者:
解利平、林 涛、束 坤、冯 磊、苏 龙、车海江、王 鹏
710077 西安,西安西电集团医院神经外科(解利平、林 涛、束 坤、冯 磊、苏 龙、车海江、王 鹏)
Author(s):
XIE Li-ping LIN Tao SHU Kun FENG Lei SU Long CHE Hai-jiang WANG Peng.
Department of Neurosurgery, Xi’an Xidian Group Hospital, Xi’an 700077, China
关键词:
外伤性视神经病神经内镜经鼻蝶入路视神经管减压术疗效Meta分析
Keywords:
Traumatic optic neuropathy Neuroendoscope Endonasal optic canal decompression Surgical opportunity
分类号:
R 651.1+5; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2017.11.009
文献标志码:
A
摘要:
目的 使用Meta分析的方法评价内镜下经鼻蝶入路视神经管减压术治疗外伤性视神经病(TON)不同手术时机的疗效。方法 遵循循证医学的原则,采用计算机检索1991年1月至2017年1月Medline、EMBase、Cochran、CNKI、万方、维普等数据库,检索内镜下经鼻蝶入路视神经管减压术治疗TON的观察性研究文献,根据手术时机分为<3 d组和>3 d组。应用Rev.Man5.3软件进行Meta分析。结果 共纳入11篇文献,包括TON 879例。Meta分析显示:<3 d组总有效率明显高于>3 d组(OR=2.53,95% CI:1.34~4.76,P=0.004);而且,<3 d组术前未失明病人有效率明显高于>3 d组(OR=2.31,95% CI:1.12~4.79,P=0.02);对于术前失明病人,两组有效率无统计学差异(P=0.06)。结论 对于未失明TON病人,建议尽早手术;内镜下经鼻蝶入路视神经管减压术效果良好。
Abstract:
Objective To evaluate the opportunity of neuroendoscopic endonasal optic canal decompression (NEEOCD) for the traumatic optic neuropathy (TON). Methods According to the principle of evidence-based medicine, the data bases such as Medline, EMBase, Cochran library, CNKI,WANFANG and VIP were searched in order to retrieve the original articles of NEEOCD for TON from January, 1991 to January, 2017. Meta-analysis and data processing were done by the Rev. Man5.3 software. Results A total of 11 original articles including 879 patients with TON undergoing NEEOCD were involved in the meta-analysis. Meta-analysis showed that the total effective rate was significantly higher in the patients with TON who underwent NEEOCD within 3 days after the injury than that in the patients with TON undergoing NEEOCD more than 3 days after the injury [OR (95%CI) 2.53 (1.34,4.76); P<0.01]. The effective rate was significantly higher in the TON patients without preoperative blinding who underwent NEEOCD within 3 days after the injury than that in the TON patients without preoperative blinding who underwent NEEOCD more than 3 days after the injury [OR (95%CI) 2.31 (1.12, 4.79); P=0.02]. Conclusion It is suggested that NEEOCD should be performed as early as possible in order to improve the prognoses in the patients with TON.

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备注/Memo

备注/Memo:
通讯作者:林 涛,E-mail:lintao417@126.com
更新日期/Last Update: 2017-09-12