[1]曹成龙 李艳玲 卢锦江 宋 健 徐国政.晚期正电位技术在垂体腺瘤病人情绪加工功能障碍评估中的应用[J].中国临床神经外科杂志,2020,(12):817-820.[doi:10.13798/j.issn.1009-153X.2020.12.001]
 CAO Cheng-long,LI Yan-ling,LU JIn-jiang,et al.Application of late positive potential techniques in evaluation of emotional-processing dysfunction of patients with pituitary adenoma[J].,2020,(12):817-820.[doi:10.13798/j.issn.1009-153X.2020.12.001]
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晚期正电位技术在垂体腺瘤病人情绪加工功能障碍评估中的应用()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2020年12期
页码:
817-820
栏目:
论著
出版日期:
2020-12-25

文章信息/Info

Title:
Application of late positive potential techniques in evaluation of emotional-processing dysfunction of patients with pituitary adenoma
文章编号:
1009-153X(2020)12-0817-04
作者:
曹成龙 李艳玲 卢锦江 宋 健 徐国政
510515 广州,南方医科大学第一临床医学院(曹成龙、卢锦江、徐国政);430060 武汉,中国人民解放军中部战区总医院神经外科(李艳玲、宋 健、徐国政)
Author(s):
CAO Cheng-long1 LI Yan-ling2 LU JIn-jiang1 SONG Jian2 Xu Guo-zheng12.
1. First Clinical Medical College, Southern Medical University, Guangzhou 510515, China; 2. Department of Neurosurgery, General Hospital of Central Theater Command, PLA, Wuhan 430070, China
关键词:
垂体腺瘤事件相关电位技术晚期正电位情绪加工功能障碍
Keywords:
Pituitary adenoma Emotional-processing dysfunction Late positive potential
分类号:
R 739.41
DOI:
10.13798/j.issn.1009-153X.2020.12.001
文献标志码:
A
摘要:
目的 探讨晚期正电位(LPP)在垂体腺瘤病人情绪加工功能障碍评估中的应用价值。方法 2018年6月2019年12月前瞻性收集26例垂体腺瘤和26例健康志愿者(对照组),使用10-20国际标准化系统记录头皮中央、顶部脑电数据,头皮电阻降到5 kΩ以下,采样率为1 000 Hz,滤波带宽在0.05~200 Hz;从国际情感图片系统中选择45张图片,包括15幅正性刺激图像、15幅负性刺激图像和15幅中性刺激图像。结果 无论是垂体腺瘤病人,还是健康志愿者,正性刺激和中性刺激均可以诱发出显著的LPP成分;与中性刺激引起的LPP振幅相比,正性刺激诱发的两侧顶叶LPP振幅更大(P<0.05)。负性刺激情况下,对照组LPP振幅[(2.435±0.419)μV]显著大于垂体腺瘤组[(0.656±0.427)μV;P=0.005];正性刺激情况下,对照组LPP振幅[(1.450±0.316)μV]也显著大于垂体腺瘤组[(0.495±0.322)μV;P=0.040]。对照组右侧顶叶LPP振幅[(1.993±0.299)μV]显著大于垂体腺瘤组[(0.269±0.305)μV;P=0.001]。结论 垂体腺瘤病人存在情绪加工功能障碍,提示临床除了关注垂体腺瘤本身的治疗外,还要重视病人的情绪加工能力障碍。
Abstract:
Objective To explore the value of late positive potential (LPP) elicited by affective stimuli in the evaluation of emotional-processing dysfunction (EPD) of the patients with pituitary adenoma (PA). Methods Twenty-six patients with PA (PA group) and 26 healthy volunteers (control group) were prospectively recruited from June 2018 to December 2019. The international 10-20 EEG system was used to record the central-parietal EEG data. Evaluation of emotional stimuli processing by LPP was carried out through central-parietal electrode sites (C3, Cz, C4, P3, Pz, P4) on the head. Picture stimuli were taken from the IAPS, including 15 positive pictures, 15 negative pictures and 15 neutral pictures. Results Both positive and neutral stimuli could induce significant LPP components in both groups. Compared with the LPP amplitude caused by neutral stimuli, the LPP amplitude of parietal lope significantly increased in both groups (P<0.05). The LPP amplitude induced by negative stimuli of the control group [(2.435±0.419) μV] was significantly higher than that [(0.656±0.427) μV] of the PA group (P<0.05). The LPP amplitude induced by positive stimuli of the control group [(1.450±0.316) μV] was significantly higher than that [(0.495±0.322)μV] of the PA group (P<0.05). The LPP amplitude of the right parietal lobe of the control group [(1.993±0.299) μV] was significantly higher than that [(0.269±0.305) μV] of the PA group (P<0.05). Conclusion For PA patients, clinical attention should also be paid to patients’ EPD in addition to the treatment of PA.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81571049;81870863)通讯作者:徐国政,E-mail:docxgz@163.com
更新日期/Last Update: 2020-12-25