[1]李　明,党　伟,胡志卿,等.早期栓塞和手术夹闭颅内破裂动脉瘤的疗效及安全性[J].中国临床神经外科杂志,2016,(12):759-761.[doi:10.13798/j.issn.1009-153X.2016.12.009]
　LI Ming,DANG Wei,HU Zhi-qing,et al.Evaluation of effect of early interventional treatment on ruptured incranial aneurysms and its safety[J].,2016,(12):759-761.[doi:10.13798/j.issn.1009-153X.2016.12.009]
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早期栓塞和手术夹闭颅内破裂动脉瘤的疗效及安全性()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2016年12期
页码:
759-761
栏目:
论著
出版日期:
2016-12-25

文章信息/Info

Title:
Evaluation of effect of early interventional treatment on ruptured incranial aneurysms and its safety
文章编号:
1009-153X（2016）12-0759-03
作者:
李　明; 党　伟; 胡志卿; 曾振东; 陈雪江; 魏川江; 林超群
518016 广东，深圳市光明新区人民医院神经外科（李　明,党　伟,胡志卿,曾振东,陈雪江,魏川江,林超群）；518037 广东，深圳市第二人民医院神经外科（丁建军）
Author(s):
LI Ming1;  DANG Wei1;  HU Zhi-qing1;  ZENG Zhen-dong1;  CHEN Xue-jiang1;  WEI Chuan-jiang1;  LIN Chao-qun1;  DING Jian-jun2
1. Department of Neurosurgery, People’s Hospital, Guangming New District of Shenzhen City, Shenzhen 518106, China; 2. Department of Neurosurgery, The Second People’s Hospital, Shenzhen city, Shenzhen 518037, China
关键词:
颅内破裂动脉瘤; 栓塞治疗; 夹闭术; 疗效; 安全性; 基层医院
Keywords:
Ruptured intracranial aneurysms;  Interventional therapy;  Curative effect;  Safety
分类号:
R 743.9; R 651.1+2
DOI:
10.13798/j.issn.1009-153X.2016.12.009
文献标志码:
A
摘要:
目的 探讨基层医院早期栓塞和手术夹闭颅内破裂动脉瘤的疗效及安全性。方法 2014年5月至2016年4月收治颅内破裂动脉瘤68例，其中早期栓塞治疗33例（栓塞组），手术夹闭治疗35例（夹闭组）。结果 术后1周，栓塞组NIHSS评分明显优于夹闭组（P<0.05）。术后随访3个月，栓塞组术后癫痫和缺血性脑梗死发生率均显著低于夹闭组（P<0.05）；两组脑积水发生率无明显差异（P>0.05）。栓塞组术后3个月存活率（96.97%，32/35）与夹闭组（88.57%，31/33）无显著差异（P>0.05）。结论 具备开展颅内动脉瘤的治疗条件的基层医院早期栓塞与开颅夹闭颅内破裂动脉瘤均具良好的疗效和安全性，但栓塞并发症较少。
Abstract:
Objective To explore the curative effect of interventional therapy early after the rupture on the ruptured intracranial aneurysms and its safety in the primary hospital. Methods Sixty-eight patients with ruptured intracranial aneurysms were randomly divided into two groups, i.e. observed group, in which 33 patients received interventional treatment and control group, in which 35 received craniotomy for clapping the aneurysms early after the rupture. (USA) National Institutes of Health stroke Scale (NIHSS) scores were determined before and 1 week after the treatment in both the groups. The prognoses were compared between both the groups 3 months after the treatment. Results NIHSS scores were significantly lower in the observed group than those in the control group 1 week after the treatment (P<0.05). The incidence (21.2%) of postoperative complications including epilepsy, ischemic cerebral infarction and hydrocephalus was significantly lower in the observed group than that (54.3%) in the control group 3 months after the treatment (P< 0.05). There was insignificant difference in the survival rate 3 months after the treatment between both the groups (P>0.05). Conclusion The curative effect of interventional treatment early after the rupture on the ruptured intracranial aneurysms and its safety are good.

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备注/Memo

备注/Memo:
作者单位：518016 广东，深圳市光明新区人民医院神经外科（李　明,党　伟,胡志卿,曾振东,陈雪江,魏川江,林超群）；518037 广东，深圳市第二人民医院神经外科（丁建军）
更新日期/Last Update: 1900-01-01