[1]郑云贵　卢晓闻　许烈鹏　袁　军.颅内破裂微小动脉瘤预后的影响因素分析[J].中国临床神经外科杂志,2017,(09):634-635638.[doi:10.13792017.09/j.issn.1009-153X.2017.09.008]
　ZHENG Yun-gui,LU Xiao-wen,XU Lie-peng,et al.Analysis of factors related to prognoses in the patients with very small ruptured intracranial aneurysms treated by surgery[J].,2017,(09):634-635638.[doi:10.13792017.09/j.issn.1009-153X.2017.09.008]
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颅内破裂微小动脉瘤预后的影响因素分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年09期
页码:
634-635638
栏目:
论著
出版日期:
2017-09-25

文章信息/Info

Title:
Analysis of factors related to prognoses in the patients with very small ruptured intracranial aneurysms treated by surgery
文章编号:
1009-153X（2017）09-0634-02
作者:
郑云贵　卢晓闻　许烈鹏　袁　军
515041 广东汕头，汕头大学医学院第一附属医院神经外科
Author(s):
ZHENG Yun-gui;  LU Xiao-wen;  XU Lie-peng;  YUAN Jun.
Department of Neurosurgery, First Affiliated Hospital, Medical School, Shantou University, Shantou 515041, China
关键词:
颅内破裂动脉瘤; 颅内微小动脉瘤; 预后; 影响因素
Keywords:
Very small intracranial aneurysm;  Relationship;  Prognosis;  Factors;  Analysis
分类号:
R 743.9
DOI:
10.13792017.09/j.issn.1009-153X.2017.09.008
文献标志码:
A
摘要:
目的 探讨颅内破裂微小动脉瘤预后的影响因素。方法 回顾性分析2012年11月至2016年8月手术治疗的63例颅内破裂微小动脉瘤的临床资料，采用多因素Logistic回归分析检验预后影响因素。结果 术后6个月，采用GOS评分评估预后，预后良好（GOS评分4~5分）41例，预后不良22例。多因素Logistic回归分析显示入院时Hunt-Hess分级>Ⅲ级（OR=11.453，95%CI：1.888~69.495，P=0.008）、合并脑内血肿（OR=6.665，95%CI：1.298~34.236，P=0.023）、合并脑梗死（OR=11.353，95%CI：1.909~67.520，P=0.008）是影响破裂颅内微小动脉瘤病人预后的独立影响因素。结论 颅内破裂微小动脉瘤入院时Hunt-Hess分级>Ⅲ级、合并脑内血肿、合并脑梗死，预后较差。这些因素可评估此类病人近期预后，指导临床诊治。
Abstract:
Objective To study factors related to the prognoses in the patients with very small ruptured intracranial aneurysms after the surgery. Methods The clinical data of 63 patients with very small ruptured intracranial aneurysms, who received surgical or endovascular treatment in our hospital from November, 2012 to August, 2016, were analyzed retrospectively. The relationships of prognoses with the factors including the patients’ age and gender, operative approach and opportunity, Fisher Scale and Hunt-Hess classification on admission to hospital, intracerebral hematoma, and cerebral infraction were analyzed by univariate and multivariable logistic regression analyses. Results The univariate analysis showed that prognoses of patients with very small ruptured intracranial aneurysms were affected by Fisher Scale and Hunt-Hess classification on admission to hospital, intracerebral hematoma and cerebral infraction (P<0.01). The multivariate logistic regression analysis showed that Hunt-Hess classification (>grade Ⅲ) on admission to hospital (OR=11.453, 95%CI: 1.888~69.495, P=0.008), intracerebral hematoma (OR=6.665, 95%CI: 1.298~34.236, P=0.023) and cerebral infraction (OR=11.353, 95%CI: 1.909~67.520, P=0.008) were independent risk factors affecting the prognoses in the patients with very small ruptured intracranial aneurysms. Conclusion The patients’ Hunt-Hess classification on admission to hospital and whether patients were complicated by intracerebral hematomas and cerebral infractions are of high value to predicting the prognoses in the patients with very small intracranial aneurysms.

参考文献/References:

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备注/Memo

备注/Memo:
作者单位：515041 广东汕头，汕头大学医学院第一附属医院神经外科（郑云贵、卢晓闻、许烈鹏、袁　军） 通讯作者：袁　军，E-mail：yjun116@163.com
更新日期/Last Update: 1900-01-01