[1]陈鹤,赵玉龙,刘佳明,等.前交通动脉破裂动脉瘤术后认知功能障碍的影响因素[J].中国临床神经外科杂志,2022,27(05):366-369.[doi:10.13798/j.issn.1009-153X.2022.05.010]
　CHEN He,ZHAO Yu-long,LIU Jia-ming,et al.Risk factors for postoperative cognitive imparment in patients with ruptured anterior communicating aneurysm[J].,2022,27(05):366-369.[doi:10.13798/j.issn.1009-153X.2022.05.010]
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前交通动脉破裂动脉瘤术后认知功能障碍的影响因素()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
27
期数:
2022年05期
页码:
366-369
栏目:
论著
出版日期:
2022-05-31

文章信息/Info

Title:
Risk factors for postoperative cognitive imparment in patients with ruptured anterior communicating aneurysm
文章编号:
1009-153X(2022)05-0366-04
作者:
陈鹤; 赵玉龙; 刘佳明; 杜舜尧; 唐一淳; 陈立刚; 高旭
110016沈阳，中国人民解放军北部战区总医院神经外科（陈鹤、赵玉龙、刘佳明、杜舜尧、唐一淳、陈立刚、高旭）；110121沈阳，中国医科大学（陈鹤）
Author(s):
CHEN He1; 2;  ZHAO Yu-long1;  LIU Jia-ming1;  DU Shun-yao1;  TANG Yi-chun1;  CHEN Li-gang1;  GAO Xu1 1
Department of Neurosurgery, General Hospital of Northern Theater Command, PLA, Shenyang 110000, China; 2. China Medical University, Shenyang 110000, China
关键词:
颅内破裂动脉瘤; 前交通动脉; 开颅夹闭术; 介入治疗; 认知功能障碍; 影响因素
Keywords:
Ruptured intracranial aneurysm;  Anterior communicating artery;  Clipping;  Interventional therapy;  Cognitive imparment;  Risk factor
分类号:
R743.9
DOI:
10.13798/j.issn.1009-153X.2022.05.010
文献标志码:
A
摘要:
目的 探讨前交通动脉破裂动脉瘤术后发生认知功能障碍的影响因素。方法 回顾性分析 2017年1月至2020年2月手术治疗的204例前交通动脉破裂动脉瘤的临床资料。术后随访20~57个月，平均（36.7±9.4）个月；末次随访时，应用修订版认知功能电话问卷（TICS-m）评分评估认知功能，其中TICS-m评分≤27分认为存在认知功能障碍。结果 57例术后存在认知功能障碍，发生率为27.9%。多因素logistic回归分析显示，高血压病、开颅夹闭术、小学及以下教育程度是术后发生认知功能障碍的独立影响因素（P<0.05）。结论 前交通动脉破裂动脉瘤术后认知功能障碍发生率较高；治疗方法上，优先选择介入治疗，术后认知功能障碍风险低于夹闭术。另外，高血压病及病人受教育水平也与术后认知功能障碍密切相关。
Abstract:
Objective To investigate the risk factors of postoperative cognitive imparment in the patients with ruptured anterior communicating artery aneurysm. Methods The clinical data of 204 patients with ruptured anterior communicating artery aneurysm who underwent operation from January 2017 to February 2020 were retrospectively analyzed. The follow up ranged from 20 months to 57 months, with an average of (36.7±9.4) months. At the last follow-up, the Telephone Interview for Cognitive Status-Modified (TICS-m) score was used to evaluate the cognitive function. The patients who had a TICS-m score ≤27 was classified as cognitive imparment. Results Fifty-seven of 204 patients had cognitive dysfunction after the operation, and the incidence rate was 27.9%. Multivariate logistic regression analysis showed that hypertension, clipping, and education level below primary school were independent risk factors for the postoperative cognitive dysfunction (P<0.05). Conclusions The incidence of cognitive dysfunction after operation in the patients with anterior communicating artery aneurysm is relatively high. Interventional therapy, which has lower risk of cognitive dysfunction, is preferred to clipping. In addition, hypertension and patient education level are also closely related to the postoperative cognitive imparment.

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备注/Memo

备注/Memo:
基金项目：辽宁省自然科学基金（2021-KF-12-02）
通讯作者：高　旭，E-mail：goelmer@hotmail.com　陈立刚，E-mail：clg201820271@126.com
更新日期/Last Update: 2022-06-30