[1]林昆哲　袁邦清　黄绍宽　杨　光　叶忠兴　林杨杨.生长激素型与无功能型垂体腺瘤的垂体后叶MRI高信号影分析[J].中国临床神经外科杂志,2017,(03):158-161.[doi:10.13798/j.issn.1009-153X.2017.03.010]
　LIN Kun-zhe,YUAN Bang-qing,HUANG Shao-kuan,et al.Analysis of posterior pituitary hyperintense signal on MRI in patients with growth hormone-secreting and nonfunctional pituitary adenomas[J].,2017,(03):158-161.[doi:10.13798/j.issn.1009-153X.2017.03.010]
点击复制

生长激素型与无功能型垂体腺瘤的垂体后叶MRI高信号影分析()
分享到：

《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年03期
页码:
158-161
栏目:
论著
出版日期:
2017-03-20

文章信息/Info

Title:
Analysis of posterior pituitary hyperintense signal on MRI in patients with growth hormone-secreting and nonfunctional pituitary adenomas
文章编号:
1009-153X（2017）03-0158-04
作者:
林昆哲　袁邦清　黄绍宽　杨　光　叶忠兴　林杨杨
350002 福州，南京军区福州总医院476临床部神经外科
Author(s):
LIN Kun-zhe;  YUAN Bang-qing;  HUANG Shao-kuan;  YANG Guang;  YE Zhong-xing;  LIN Yang-yang
Department of Neurosurgery, 476th Clinical Branch, Fuzhou General Hospital, PLA, Fuzhou 350002, China
关键词:
生长激素型垂体腺瘤; 无功能型垂体腺瘤; 垂体后叶亮点; 磁共振成像
Keywords:
Nonfunctional pituitary adenomas;  Growth hormone-secreting adenomas;  Posterior pituitary;  Hyperintense signal;  MRI
分类号:
R 739.41; R 445.2
DOI:
10.13798/j.issn.1009-153X.2017.03.010
文献标志码:
A
摘要:
目的 探讨生长激素型与无功能型垂体腺瘤的垂体后叶MRI高信号影的特点。方法 回顾性分析45例无功能型垂体腺瘤与16例生长激素型垂体腺瘤的MRI影像资料。结果 45例无功能型垂体腺瘤中，39例可见垂体后叶高信号影，其中位于鞍上24例，鞍内3例，鞍内及鞍上均可见12例；16例生长激素型垂体腺瘤中，15例出现垂体后叶高信号影，其中位于鞍上1例，鞍内14例。无功能型垂体腺瘤的体积明显大于生长激素型腺瘤体积（P<0.05），向鞍上及海绵窦侵犯的发生率明显高于生长激素型垂体腺瘤（P<0.05），而向鞍下侵犯及局限于垂体窝内生长的发生率低于生长激素型垂体腺瘤（P<0.05）。无功能型与生长激素型垂体腺瘤垂体后叶高信号影的最长径线分别为（8.32±3.37）mm、（5.83±1.64）mm，最短径线分别为（1.67±0.33）mm、（2.23±0.75）mm，差异有统计学意义（P<0.05）。结论 生长激素型与无功能型垂体腺瘤的生长特点不同，其垂体后叶MRI高信号影的表现形式也不同。
Abstract:
Objective To compare the characteristics of MRI of the posterior pituitary hyperintense signals (PPHIS) between growth hormone-secreting pituitary adenomas (GHPAs) and nonfunctional pituitary adenomas (NFPAs). Method The data of MRI in 45 patients with NFPAs and 16 patients with GHPAs were analyzed retrospectively. Results PPHIS on MRI were observed in 39 patients with NFPAs, of whom, 21 (53.8%, 21/39) had the suprasellar hyperintense signals on MRI, 6 (15.4%, 6/39) intrasellar and 12 (30.8%, 12/39) supra- and infrasellar. PPHIS on MRI were observed in 15 (93.7%, 15/16) patients with GHPAs, of whom, 13 (86.7%, 13/15) had the intrasellar hyperintense signal and 1 (6.7%, 1/15) suprasellar and 1 (6.7%, 1/15) supra- and infrasellar. There were significant differences in the percentages of the patients with suprasellar, intrasellar and supra- and infrasellar hyperintense signals between the patients with GHPAs and the ones with NFPAs (P<0.05). The mean lengths were (8.32±3.37) mm in the long axis and (1.67±0.33) mm in the short axis of NFPAs hyperintense signal. And the mean lengths were (5.83±1.64) mm in the long axis and (2.23±0.75) mm in the short axis of GHPAs hyperintense signal. There were significant differences in the lengths of the long and short axes of hyperintense signal between GHPAs and NFPAs (P<0.05). Conclusion The growth patterns of NFPAs and GHPAs are different from each other, and the manifestations of their PPHIS pituitary signal on MRI are also different from each other.

参考文献/References:

[1] Saeki N, Hayasaka M, Murai H, et al. Posterior pituitary bright spot in large adenomas: MR assessment of its disa- ppearance or relocation along the stalk [J]. Radiology, 2003, 226(2): 359-365.
[2] C?té M, Salzman KL, Sorour M, et al. Normal dimensions of the posterior pituitary bright spot on magnetic resonance imaging [J]. J Neurosurg, 2014, 120(2): 357-362.
[3] Zada G, Lin N, Laws Jr ER. Patterns of extrasellar extension in growth hormone-secreting and nonfunctional pituitary macroadenomas [J]. Neurosurg Focus, 2010, 29(4): 204- 208.
[4] 朱丹化，吴哲褒，陈贤斌，等. 垂体生长激素大腺瘤和无功 能大腺瘤的生长模式分析[J]. 中华神经外科杂志，2012， 28（1）：59-62.
[5] Wang S, Wei L, Zhao L, et al. Analysis of operative efficacy for giant pituitary adenoma [J]. BMC Surg, 2014, 14(1): 59- 65.
[6] Di Maio S, Biswas A, Vézina J L, et al. Pre- and post- operative magnetic resonance imaging appearance of the normal residual pituitary gland following macroadenoma resection: clinical implications [J]. Surg Neuro Int, 2012, 32 (1): 214-219.
[7] 孔令胜，姚维成，栗世方，等. 肢端肥大症型垂体腺瘤MRI 特点及其与血清GH水平、肿瘤 GH 表达水平的关系分 析[J]. 中国临床神经外科杂志，2014，19（9）：516-518.
[8] Hagiwam A, Inoue Y, Wakasa K. Comparion of growth hormone-producing and nongrowth hormone-producing pituitary adenomas：imaging characteristics and pathologic correlation [J]. Radiology, 2003, 228: 533-538.
[9] Rajaratnam S. Pituitary gland imaging [J]. Indian J Endo- crinol Metab, 2013, 17(Suppl1): S100.
[10] Yamamoto A, Oba H, Furui S. Influence of age and sex on signal intensities of the posterior lobe of the pituitary gland on T1-weighted images from 3 T MRI [J]. Jpn J Radiol, 2013, 31(3): 186-191.
[11] Fujisawa I. Magnetic resonance imaging of the hypothalamic neurohypophyseal system [J]. J Neuroendocrinol, 2004, 16 (4): 297-302.
[12] Bonneville F, Narboux Y, Cattin F, et al. Preoperative loca- tion of the pituitary bright spot in patients with pituitary macroadenomas [J]. Am J Neuroradiol, 2002, 23: 528-532.
[13] 刘伟明，贾桂军，关树森，等. 垂体大腺瘤手术前后垂体后 叶高信号的变化[J]. 北京医学，2008，30（10）：600-603.

相似文献/References:

[1]徐志明,李胜利,李彤,等.假包膜外切除术治疗无功能型垂体腺瘤的疗效[J].中国临床神经外科杂志,2022,27(05):382.[doi:10.13798/j.issn.1009-153X.2022.05.015]

备注/Memo

备注/Memo:
基金项目：2015年军区课题基金（15MS149）；福建省自然科学基金（2015D014）
通讯作者：袁邦清，E-mail：ytt838l2280@sina.com
更新日期/Last Update: 2017-03-25