[1]张利超 综述 张 强 审校.颅脑损伤后BDNF及其小分子模拟物的治疗潜力[J].中国临床神经外科杂志,2018,(11):760-762.[doi:10.13798/j.issn.1009-153X.2017.11.021]
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颅脑损伤后BDNF及其小分子模拟物的治疗潜力()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年11期
页码:
760-762
栏目:
论著
出版日期:
2018-11-25

文章信息/Info

作者:
张利超 综述 张 强 审校
810000 西宁,青海大学研究生院(张利超);810007 西宁,青海省人民医院神经外科(张 强)
关键词:
颅脑损伤78-二羟基黄酮脑源性神经营养因子原肌球蛋白相关激酶B受体(TrkB)
分类号:
R 651.1+5
DOI:
10.13798/j.issn.1009-153X.2017.11.021
文献标志码:
A

参考文献/References:


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[2] Leal G, Afonso PM, Salazar IL, et al. Regulation of hippo- campal synaptic plasticity by BDNF [J]. Brain Res, 2015, 1621: 82-101.
[3] Skaper SD.The neurotrophin family of neurotrophic factors: an overview [J]. Methods Mol Biol, 2012, 846: 1-12.
[4] Marco-Salazar P, Marquez M, Fondevila D, et al. Mapping of neurotrophins and their receptors in the adult mouse brain and their role in the pathogenesis of a transgenic murine model of bovine spongiform encephalopathy [J]. J Comp Pathol, 2014, 150(4): 449-462.
[5] Skaper SD. The biology of neurotrophins,signalling path- ways, and functional peptide mimetics of neurotrophins and their receptors [J].CNS Neurol Disord Drug Targets, 2008, 7 (1): 46-62.
[6] Bernard-Gauthier V, Boudjemeline M, Rosa-Neto P, et al. Towards tropomyosin-related kinase B (TrkB) receptor ligands for brain imaging with PET: radiosynthesis and evaluation of 2-(4-[(18)F]fluorophenyl)-7,8-dihydroxy- 4H-chromen-4-one and 2-(4-([N-methyl-(11)C]- dimethylamino)phenyl)-7,8-dihydroxy-4H-chromen-4- one [J]. Bioorg Med Chem, 2013, 21(24): 7816-7829.
[7] Bollen E, Vanmierlo T, Akkerman S, et al. 7,8-Dihydroxy- flavone improves memory consolidation processes in rats and mice [J]. Behav Brain Res, 2013, 257: 8-12.
[8] Castello NA, Nguyen MH, Tran JD, et al. 7,8-Dihydroxyfla- vone, a small molecule TrkB agonist,improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss [J]. PLoS One, 2014, 9(3): e91453.
[9] Zeng Y, Liu Y, Wu M, et al. Activation of TrkB by 7,8- dihydroxyflavone prevents fear memory defects and facili- tates amygdalar synaptic plasticity in aging [J]. J Alzheimers Dis, 2012, 31(4): 765-778.
[10] Leal G, Comprido D, Duarte CB. BDNF-induced local pro- tein synthesis and synaptic plasticity [J]. Neuropharmaco- logy, 2014, 76 Pt C: 639-656.
[11] Khalin I, Alyautdin R, Wong TW, et al. Brain-derived neu- rotrophic factor delivered to the brain using poly (lactide- co-glycolide) nanoparticles improves neurological and cognitive outcome in mice with traumatic brain injury [J]. Drug Deliv, 2016, 23(9): 3520-3528.
[12] Jang SW, Liu X, Yepes M, et al. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyfla- vone [J]. Proc Natl Acad Sci USA, 2010, 107(6): 2687- 2692.
[13] Liu X, Obianyo O, Chan CB, et al. Biochemical and biophy- sical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor [J]. J Biol Chem, 2014, 289(40): 27571-27584.
[14] Zhang Z, Liu X, Schroeder JP, et al. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease [J]. Neuropsychopharmaco- logy, 2014, 39(3): 638-650.
[15] Jiang M, Peng Q, Liu X, et al. Small-molecule TrkB recep- tor agonists improve motor function and extend survival in a mouse model of Huntington's disease [J]. Hum Mol Genet, 2013, 22(12): 2462-2470.
[16] Wu CH, Hung TH, Chen CC, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling [J]. PLoS One, 2014, 9(11): e113397.
[17] Agrawal R, Noble E, Tyagi E, et al. Flavonoid derivative 7, 8-DHF attenuates TBI pathology via TrkB activation [J]. Biochim Biophys Acta, 2015, 1852(5): 862-872.
[18] Chen L, Gao X, Zhao S, et al. The small-molecule trkb ago- nist 7,8-dihydroxyflavone decreases hippocampal newborn neuron death after traumatic brain injury [J]. J Neuropathol Exp Neurol, 2015, 74(6): 557-567.
[19] Park HY, Park C, Hwang HJ, et al. 7,8-Dihydroxyflavone attenuates the release of pro-inflammatory mediators and cytokines in lipopolysaccharide-stimulated BV2 microglial cells through the suppression of the NF-kappaB and MAPK signaling pathways [J]. Int J Mol Med, 2014, 33(4): 1027- 1034.

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备注/Memo

备注/Memo:
基金项目:青海省科技厅项目(2016-ZJ-783) 作者单位:810000 西宁,青海大学研究生院(张利超);810007 西宁,青海省人民医院神经外科(张 强) 通讯作者:张 强,E-mail:zhangqiang691212@163.com
更新日期/Last Update: 2018-11-20