[1]孙雪娟、童孜蓉.创伤性颅内出血病人并发深静脉血栓形成的危险因素[J].中国临床神经外科杂志,2019,(10):592-594.[doi:10.13798/j.issn.1009-153X.2019.10.005]
　SUN Xue-juan,TONG Zi-rong.Analysis of risk factors related to deep venous thrombosis in patients with traumatic intracranial hemorrhage[J].,2019,(10):592-594.[doi:10.13798/j.issn.1009-153X.2019.10.005]
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创伤性颅内出血病人并发深静脉血栓形成的危险因素()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2019年10期
页码:
592-594
栏目:
论著
出版日期:
2019-10-20

文章信息/Info

Title:
Analysis of risk factors related to deep venous thrombosis in patients with traumatic intracranial hemorrhage
文章编号:
1009-153X（2019）10-0592-03
作者:
孙雪娟、童孜蓉
210000 南京，江苏省人民医院神经外科（孙雪娟、童孜蓉）
Author(s):
SUN Xue-juan;  TONG Zi-rong
Department of Neurosurgery, Jiangsu Provincial People's Hospital, Nanjing 210000, China
关键词:
颅脑损伤; 颅内出血; 深静脉血栓形成; 危险因素
Keywords:
Cerebral trauma;  Intracranical hemorrhage;  Deep vein thrombosis;  Risk factors
分类号:
R 651.1+5
DOI:
10.13798/j.issn.1009-153X.2019.10.005
文献标志码:
A
摘要:
目的 探讨创伤性颅内出血病人并发深静脉血栓形成的危险因素。方法 回顾性分析2015年6月至2018年6月收治的260例创伤性颅内出血病人的临床资料。使用多因素logistics回归分析检验创伤性颅内出血病人并发深静脉血栓形成的危险因素。结果 260例中，60例并发深静脉血栓形成，发生率为23.1%。多因素logistics回归分析显示出血量>50 ml、入院GCS评分≤8分、多发伤、急性生理与慢性健康量表Ⅱ评分≥20分、合并糖尿病、机械通气、住院时间≥30 d、术后下床活动时间≥7 d、血清D-二聚体≥1.5 ng/ml是创伤性颅内出血病人并发深静脉血栓形成的独立危险因素（P<0.05）。结论 创伤性颅内出血病人继发深静脉血栓形成的发生率较高，病情重、多发伤、合并糖尿病、术后下床活动延迟和血清D-二聚体水平增高是创伤性颅内出血病人并发深静脉血栓形成的独立危险因素。
Abstract:
Objective To investigate the risk factors related to deep venous thrombosis in the patients with traumatic cerebral hemorrhage (TCH). Methods Of 260 patients with TCH treated in our hospital from June , 2015 to June, 2018, 60 (observed group) were complicated with deep venous thrombosis and 200 (control group) not. The factors related to the deep venous thrombosis were statistically analyzed. Results The univariate analysis showed that the factors related to the deep venous thrombosis included the bleeding volume, GCS point, multiple injury and acute physiology and chronic health evaluation Ⅱ (ACPCHE) score, diabetes mellitus, mechanical ventilation, time of lying in bed after the operation and plasma level of D-dimer (P<0.05). The multivariate logistic regression analysis showed that the risk factors related to the deep venous thrombosis included the lower GCS points, multiple trauma, higher APACHE Ⅱ scores, diabetes mellitus, mechanical ventilation, longer time of lying in bed after the operation and higher plasma level of D-dimer in the patients with TCH (P<0.05). Conclusion The incidence of deep venous thrombosis is high in the patients with TCH, especially in the TCH patients who have severe brain injury, or associated multiple injuries, or diabetes mellitus, or higher plasma level of D-dimer and who receive mechanical ventilation.

参考文献/References:

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备注/Memo

备注/Memo:
（2019-04-16收稿，2019-05-28修回）通讯作者：童孜蓉，E-mail：njhdwang@hotmail.com
更新日期/Last Update: 2019-10-20