[1]罗　磊　朱海涛　徐宏浩等.脑磁图累积源成像在药物难治性颞叶癫痫术前评估中的应用[J].中国临床神经外科杂志,2021,26(02):72-76.[doi:10.13798/j.issn.1009-153X.2021.02.003]
　LUO Lei,ZHU Hai-tao,XU Hong-hao,et al.Application of magnetoencephalographic accumulated source imaging in preoperative assessment of patients with refractory temporal lobe epilepsy[J].,2021,26(02):72-76.[doi:10.13798/j.issn.1009-153X.2021.02.003]
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脑磁图累积源成像在药物难治性颞叶癫痫术前评估中的应用()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
26
期数:
2021年02期
页码:
72-76
栏目:
论著
出版日期:
2021-02-25

文章信息/Info

Title:
Application of magnetoencephalographic accumulated source imaging in preoperative assessment of patients with refractory temporal lobe epilepsy
文章编号:
1009-153X（2021）02-0072-03
作者:
罗　磊　朱海涛　徐宏浩等
210009 南京，南京医科大学附属脑科医院功能神经外科（罗　磊、朱海涛、徐宏浩、张　锐）
Author(s):
LUO Lei;  ZHU Hai-tao;  XU Hong-hao;  et al
Department of Functional Neurosurgery, Brain Hospital Affiliated of Nanjing Medical University, Nanjing 210000, China
关键词:
难治性颞叶癫痫; 术前评估; 脑磁图累积源成像
Keywords:
Refractory temporal lobe epilepsy;  Magnetoencephalogram;  Preoperative assessment
分类号:
R 742.1; R 445.9
DOI:
10.13798/j.issn.1009-153X.2021.02.003
文献标志码:
A
摘要:
目的 探讨脑磁图累积源成像（MEG）在难治性颞叶癫痫术前评估中的应用价值。方法 回归分析法2006年1月至2018年1月手术治疗的11例难治性颞叶癫痫临床资料。使用MRI、长程视频脑电图、MEG以及颅内电极脑电图（IEEG）帮助定位致痫灶并制定手术方案，术后随访1年，按Engel分级评估疗效。结果 MRI无明显异常5例；异常6例，其中2例与手术侧一致。11例IEEG均有异常，其中9例与手术侧一致。11例MEG均有异常，9例与手术侧一致，主要集中在4~30 Hz；MEG与IEEG一致7例。11例中，9例有效，2例无效；其中Engel分级Ⅰ级6例，Ⅱ级1例，Ⅲ级2例，Ⅳ级2例。结论 MEG分析能为难治性颞叶癫痫术前评估提供重要信息，帮助识别致痫灶和潜在癫痫网络。
Abstract:
Objective To explore the application value of the magnetoencephalographic accumulated source imaging (MEG) in the preoperative assessment of the patients with refractory temporal lobe epilepsy. Methods The clinical data of 11 patients with refractory temporal lobe epilepsy who underwent surgery from January 2006 to January 2018 were analyzed retrospectively. MRI, video-electroencephalography, MEG and intracranial electrography (IEEG) were used to locate the epileptogenic foci and help make the operative plan. All the patients were followed up for 1 year and the curative efect was assessed using Engel grade. Results For the location of epileptogenic foci, MRI showed no abnormalities in 5 patients and abnormalities in 6 of whom 2 were consistent with the surgical results; IEEG showed abnormalities in all the 11 patients of whom 9 were consistent with the operation results; MEG showed abnormalities in all the 11 patients of whom 9 were consistent with the operation results. The MEG results were consistent with IEEG in 7 patients. One year after the operation, Engel grade Ⅰ was achieved in 6 patients, grade Ⅱ in 1, grade Ⅲ in 2, and grade Ⅳ in 2. Conclusions MEG can provide important preoperative information for refractory temporal lobe epilepsy and help identify epileptogenic foci and possible epileptogenic networks.

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备注/Memo

备注/Memo:
基金项目：南京市医学科学技术发展项目（YKK17136）
通讯作者，张　锐，E-mail：neurosurgeonzr@njmu.edu.cn
更新日期/Last Update: 2021-02-25