[1]陈振寰,李梦珠,潘起航,等.细胞死亡在颅脑损伤后认知功能障碍中作用机制的研究进展[J].中国临床神经外科杂志,2024,29(02):111-114.[doi:10.13798/j.issn.1009-153X.2024.02.010]
 CHEN Zhen-huan,LI Meng-zhu,PAN Qi-hang,et al.Research progress on the mechanism of cell death in cognitive impairment after traumatic brain injury[J].,2024,29(02):111-114.[doi:10.13798/j.issn.1009-153X.2024.02.010]
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细胞死亡在颅脑损伤后认知功能障碍中作用机制的研究进展()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
29
期数:
2024年02期
页码:
111-114
栏目:
综述
出版日期:
2024-02-28

文章信息/Info

Title:
Research progress on the mechanism of cell death in cognitive impairment after traumatic brain injury
文章编号:
1009-153X(2024)02-0111-04
作者:
陈振寰李梦珠潘起航陈卓颖田亚辉夏宇李俊
430014武汉,华中科技大学附属武汉中心医院神经外科(陈振寰、李梦珠、潘起航、陈卓颖、田亚辉、夏宇、李俊)
Author(s):
CHEN Zhen-huan LI Meng-zhu PAN Qi-hang CHEN Zhuo-ying TIAN Ya-hui XIA Yu LI Jun
Department of Neurosurgery, Wuhan Central Hospital, Huazhong University of Science and Technology, Wuhan 430014, China
关键词:
颅脑损伤认知功能障碍程序性细胞死亡
Keywords:
Traumatic brain injury Cognitive impairment Programmed cell death
分类号:
R 651.1+5
DOI:
10.13798/j.issn.1009-153X.2024.02.010
文献标志码:
A
摘要:
颅脑损伤(TBI)是指外力作用于头部而引起脑组织产生的功能性或病理性改变。TBI后认知功能障碍(TBI-CI)是脑外伤后遗症的特征性表现之一。程序性细胞死亡(PCD)如凋亡、坏死性凋亡、焦亡、铁死亡及铜死亡等参与TBI-CI的病理过程。本文就PCD在TBI-CI中作用机制的研究进展进行综述,为临床TBI-CI的预防及治疗提供参考。
Abstract:
Traumatic brain injury (TBI) refers to functional or pathological changes in brain tissues caused by external forces on the head. Traumatic brain injury-related cognitive impairment (TBI-CI) is a characteristic manifestation of post-traumatic brain injury sequelae, and programmed cell death (PCD) processes such as apoptosis, necroptosis, pyroptosis, ferroptosis, and cuproptosis play a role in the pathological processes of TBI-CI. This review provides an overview of the research progress on the mechanisms of PCD in TBI-CI, aiming to offer insights for the prevention and treatment of clinical TBI-CI.

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备注/Memo

备注/Memo:
(2023-10-25收稿,2024-01-24修回) 通信作者:李 俊,Email:lj690222@sina.com
更新日期/Last Update: 2024-02-28