[1]龙强友 漆新伟 王德全.高血压性脑出血外周血炎症标志物与术后30天病死率的关系[J].中国临床神经外科杂志,2017,(05):302-304.[doi:10.13798/j.issn.1009-153X.2017.05.006]
 LONG Qiang-you,QI Xin-wei,WANG De-quan..Relationship of peripheral blood inflammatory markers with 30-day mortality after surgery in the patients with hypertensive intracerebral hemorrhage[J].,2017,(05):302-304.[doi:10.13798/j.issn.1009-153X.2017.05.006]
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高血压性脑出血外周血炎症标志物与术后30天病死率的关系()

《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年05期
页码:
302-304
栏目:
论著
出版日期:
2017-05-20

文章信息/Info

Title:
Relationship of peripheral blood inflammatory markers with 30-day mortality after surgery in the patients with hypertensive intracerebral hemorrhage
文章编号:
1009-153X(2017)05-0302-03
作者:
龙强友 漆新伟 王德全
610041,成都市第七人民医院神经外科
Author(s):
LONG Qiang-you QI Xin-wei WANG De-quan.
Department of Neurosurgery, Chengdu Municipal 7th People’s Hospital, Chengdu 610041, China
关键词:
高血压性脑出血单核细胞淋巴细胞淋巴细胞/单核细胞比值术后30 d病死率
Keywords:
Hypertensive intracerebral hemorrhage Monocyte Lymphocyte Lymphocyte-monocyte ratio Postoperative 30-day mortality
分类号:
R 743.34; R 651.1+2
DOI:
10.13798/j.issn.1009-153X.2017.05.006
文献标志码:
A
摘要:
目的 探讨外周血炎症标志物与高血压性脑出血术后30 d病死率的关系。方法 回顾性分析2012~2015年手术治疗的215例高血压性脑出血的临床资料,采用受试者工作特征(ROC)曲线法与Logistic回归分析检验炎症标志物与术后30 d病死率的关系。结果 术后30 d死亡34例。多因素Logistic回归分析后结果表明,血肿体积较大、术后第7 天淋巴细胞数较高、术后第3天淋巴细胞/单核细胞比值(LMR)较高、术后第7天LMR较高是高血压性脑出血病人术后30 d死亡的危险因素(P<0.05)。ROC曲线分析结果显示,术后第3、7天外周血LMR预测术后30 d死亡的临界值分别为1.23和1.13,其特异性、敏感性分别为70.70%、87.34%和96.60%、86.20%。结论 高血压脑性出血病人术后30 d死亡与血肿体积、外周血淋巴细胞及LMR密切相关,调整LMR或许可以改善病人预后。
Abstract:
Objective To evaluate the relationship between the peripheral blood inflammatory markers such as lymphocyte-monocyte ratio (LMR) and 30-day mortality after the surgery in patients with hypertensive intracerebral hemorrhage (HICH). Methods The clinical data of 215 patients with HICH treated by surgery in our hospital from 2012 to 2015 were analyzed retrospectively. Of these 215 patients, 34 died and 181 survived within 30 days after the treatment. The relationship of the peripheral inflammatory markers with 30-day mortality after the treatment was analyzed. Results The hematoma volume was significantly bigger and the numbers of neutrophil per liter blood 3 days after the surgery and monocyte per liter blood 7 days after the surgery, and neutrophil-lymphocyte ratio 3 and 7 days after the surgery were significantly higher in the dead patients than those in the survival patients within 30 days after the treatment (P<0.05). The number of lymphocyte per liter blood and LMR 3 and 7 days after the surgery, and preoperative platelet count and platelet-lymphocyte ratio were significantly lower in the dead patients than those in the survival patients within 30 days after the treatment(P<0.05). The multivariate analysis suggested that hematoma volume, absolute lymphocyte count 7 days after the surgery, and LMR 3 and 7 days after the surgery were related to the death within 30 days after the surgery in the patients with HICH (P<0.05). Conclusion The low level of postoperative peripheral blood LMR was risk factor of 30-day mortality after the surgery in the patients with HICH.

参考文献/References:

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备注/Memo

备注/Memo:
通讯作者:王德全,E-amil:2957363032@qq.com
更新日期/Last Update: 2017-05-20