[1]连海伟　刘仁忠　简志宏　王　峻　易　伟　杨振兴　刘　佳　王　雷.垂体腺瘤的手术治疗分析[J].中国临床神经外科杂志,2018,(12):798-799.[doi:10.13798/j.issn.1009-153X.2018.12.011]
　LIAN Hai-wei,LIU Ren-zhong,JIAN Zhi-hong,et al.Analysis of curative effect of surgery on patients with pituitary adenomas (report of 116 cases)[J].,2018,(12):798-799.[doi:10.13798/j.issn.1009-153X.2018.12.011]
点击复制

垂体腺瘤的手术治疗分析()
分享到：

《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2018年12期
页码:
798-799
栏目:
论著
出版日期:
2018-12-25

文章信息/Info

Title:
Analysis of curative effect of surgery on patients with pituitary adenomas (report of 116 cases)
文章编号:
1009-153X（2018）12-0798-02
作者:
连海伟　刘仁忠　简志宏　王　峻　易　伟　杨振兴　刘　佳　王　雷
430060 武汉，武汉大学人民医院神经外科（连海伟、刘仁忠、简志宏、王　峻、易伟、杨振兴、刘　佳、王　雷）
Author(s):
LIAN Hai-wei;  LIU Ren-zhong;  JIAN Zhi-hong;  WANG Jun;  YI Wei;  YANG Zhen-xing;  LIU Jia;  WANG Lei.
Department of Neurosurgery, Renmin Hospital, Wuhan University, Wuhan 430060, China
关键词:
垂体腺瘤; 显微手术; 疗效
Keywords:
Pituitary adenomas;  Microsurgery;  Surgical indications;  Curative effect
分类号:
R739.41;R651.1+1
DOI:
10.13798/j.issn.1009-153X.2018.12.011
文献标志码:
A
摘要:
目的 探讨垂体腺瘤的手术治疗方法及效果。方法 回顾性分析2011年2月至2017年10月手术治疗的116例垂体腺瘤的临床资料。经单侧鼻蝶 窦入路85例，标准翼点入路24例，右眉弓锁孔入路4例，冠状瓣纵裂入路3例。结果 肿瘤全切除92例，次全切除20例，大部切除3例，部分切除1例。 术后发生一过性尿崩12例，脑脊液漏6例，明显垂体功能低下5例。结论 经单侧鼻蝶窦入路是目前首选的手术方法，但对于侵袭性生长的垂体腺瘤需 根据肿瘤影像特点选择适当的手术入路。
Abstract:
Objective To evaluate the curative effect of different surgical forms on the pituitary adenomas, and their indications, merits and demerits. Methods The clinical data of 116 patients with pituitary adenomas, who underwent surgery from February, 2011 to October, 2017, were analyzed retrospectively. Of 116 patients with pituitary adenomas, 85 were treated by transnasal transphenoidal microsurgery, 24 by microsurgery via pterional approach, 4 microsurgery via right supercillary arche key hole approach and 3 by microsurgery via longtudinal approach. Results The pituitary adenomas were totally resected in 92 patients, subtotally in 20, in great part in 3 and partly in 1. Conclusions The surgical outcomes are good in these 116 patients. The pituitary adenomas confined to the sella and parasellar regions should be removed by microsurgery through transnasal transsphenoidal approach. But the invasive pituitary tumors should be by individualized microsurgery selected according to their characteristics on the images.

参考文献/References:

[1] 王国良，高　寒，张小鹏，等. 89例垂体腺瘤的手术治疗体会[J]. 中国临床神经外科杂志，2016，21（7）：435-436.
[2] 王亚平，贾晓雄，王　珺，等. 神经内镜下与显微镜下经鼻 蝶入路手术切除垂体腺瘤的疗效对比分析[J]. 中国临床 神经外科杂志，2016，21：145-146，149.
[3] 王更新，苏永永，柏鲁宁，等. 翼点入路显微手术治疗大型垂体腺瘤[J]. 山西医科大学学报，2010，41（1）：74-75.
[4] 朱贤立，张方成，赵洪洋，等. 经翼点入路显微手术治疗垂体腺瘤[J]. 中华神经外科杂志，1998，14（2）：90-93.
[5] 赵　曜，王镛斐，李士其，等. 巨大不规则型垂体腺瘤的显微外科手术治疗[J]. 中华神经外科疾病研究杂志，2007，6（1）：27-30.
[6] 程　友，程　朋，刘开东，等. 经鼻蝶入路手术治疗垂体瘤术后并发症[J]. 中国微侵袭神经外科杂志，2014，19（2）：76-77.
[7] 王洪流，陈谦学，田道锋，等. 巨大垂体腺瘤分期手术治疗分析[J]. 中国临床神经外科杂志，2015，20（8）：453-455.

相似文献/References:

[1]林国中　王振宇　马长城　赵　薇.神经电生理监测下显微手术切除脊髓髓内肿瘤[J].中国临床神经外科杂志,2015,(11):647.[doi:10.13798/j.issn.1009-153X.2015.11.003]
　LIN Guo-zhong,WANG Zhen-yu,MA Chang-cheng,et al.Clinical value of intraoperative electrophysiological monitoring to microsurgery for intramedullary spinal tumors[J].,2015,(12):647.[doi:10.13798/j.issn.1009-153X.2015.11.003]
[2]谢京城　王振宇　陈晓东.骶管终丝脊膜囊肿合并脊髓拴系综合征的诊断和治疗[J].中国临床神经外科杂志,2015,(11):651.[doi:10.13798/j.issn.1009-153X.2015.11.004]
　XIE Jing-cheng,WANG Zhen-yu,CHEN Xiao-dong.Diagnosis and surgical treatment of sacral spinal meningeal cysts of fila terminale complicated with tethered spinal cord syndrome[J].,2015,(12):651.[doi:10.13798/j.issn.1009-153X.2015.11.004]
[3]于　涛　黄正通　王振宇.椎管内脊膜囊肿的临床特征和治疗方法[J].中国临床神经外科杂志,2015,(11):654.[doi:10.13798/j.issn.1009-153X.2015.11.005]
　YU Tao,HUANG Zheng-tong,WANG Zhen-yu.Clinical features and treatment of intraspinal arachnoid cysts[J].,2015,(12):654.[doi:10.13798/j.issn.1009-153X.2015.11.005]
[4]谢宝树　王　宇　贾　锋　张　林　殷玉华.神经电生理监测下显微手术治疗成人脊髓栓系综合征[J].中国临床神经外科杂志,2015,(11):658.[doi:10.13798/j.issn.1009-153X.2015.11.006]
　XIE Bao-shu,WANG Yu,JIA Feng,et al.Intraoperative electrophysiological monitoring-guided microsurgery on tethered spinal cord syndrome in adults[J].,2015,(12):658.[doi:10.13798/j.issn.1009-153X.2015.11.006]
[5]赵东升　王正君　孙刚锋　费　舟　姬西团　李　娟　万晓强.椎管内畸胎瘤的诊断与治疗[J].中国临床神经外科杂志,2015,(11):661.[doi:10.13798/j.issn.1009-153X.2015.11.007]
　ZHAO Dong-sheng,WANG Zheng-jun,SUN Gang-feng,et al.Dignosis and treatment of intraspainal teratomas[J].,2015,(12):661.[doi:10.13798/j.issn.1009-153X.2015.11.007]
[6]陈晓东　于　涛　王振宇.脊髓髓内神经鞘瘤的诊断与治疗[J].中国临床神经外科杂志,2015,(11):670.[doi:10.13798/j.issn.1009-153X.2015.11.010]
　CHEN Xiao-dong,YU Tao,WANG Zhen-yu.Diagnosis and treatment of intramedullary spinal schwannomas[J].,2015,(12):670.[doi:10.13798/j.issn.1009-153X.2015.11.010]
[7]马　磊　张海红　张　威　衡立君　孙树凯　贾　栋.眶上锁孔入路手术切除前颅底脑膜瘤的临床效果[J].中国临床神经外科杂志,2015,(11):680.[doi:10.13798/j.issn.1009-153X.2015.11.013]
　MA Lei,ZHANG Hai-hong,ZHANG Wei,et al.Microsurgery through supraorbital keyhole approach for anterior cranial fossa meningiomas[J].,2015,(12):680.[doi:10.13798/j.issn.1009-153X.2015.11.013]
[8]李春坡　郑　军　李海元　边　涛　韩安国.侧脑室三角区小型脑膜瘤的显微外科治疗[J].中国临床神经外科杂志,2015,(11):694.[doi:10.13798/j.issn.1009-153X.2015.11.018]
[9]张兆斯　但　炜　王　刚　周　超　孙　超　谢延风　石全红　詹　彦.咪达唑仑和丙泊酚诱导麻醉对继发性癫痫术中皮层脑电图的影响[J].中国临床神经外科杂志,2016,(05):261.[doi:10.13798/j.issn.1009-153X.2016.05.002]
　ZHANG Zhao-si,DAN Wei,WANG Gang,et al.Effects of midazolam or propofol used for induction of anesthesia on intraoperative ECoG in patients with secondary epilepsy[J].,2016,(12):261.[doi:10.13798/j.issn.1009-153X.2016.05.002]
[10]赵　平　王雄伟　汪　雷　马金阳.显微手术和血管内栓塞术治疗颅内动脉瘤的疗效分析[J].中国临床神经外科杂志,2016,(05):281.[doi:10.13798/j.issn.1009-153X.2016.05.008]
　ZHAO Ping,WANG Xiong-wei,WANG Lei,et al.Effect of endovascular treatment on intracranial aneurysms: a comparison with microsurgery[J].,2016,(12):281.[doi:10.13798/j.issn.1009-153X.2016.05.008]
[11]王国良　高　寒　张小鹏　公方和　李天栋.89例垂体腺瘤的手术治疗体会[J].中国临床神经外科杂志,2016,(07):435.[doi:10.13798/j.issn.1009-153X.2016.07.016]
[12]马　涛　徐　韬.经蝶入路内镜手术与显微手术治疗垂体腺瘤疗效的Meta分析[J].中国临床神经外科杂志,2015,(12):748.[doi:10.13798/j.issn.1009-153X.2015.12.015]
[13]秦　汉　胡军民　秦海林　别毕洲　向伟楚　秦尚振　马廉亭.MRI与Dyna-CTA融合影像结合神经导航在经鼻蝶垂体腺瘤切除术中的应用[J].中国临床神经外科杂志,2015,(09):513.[doi:10.13798/j.issn.1009-153X.2015.09.001]
　QIN Han,HU Jun-ming,QIN Hai-lin,et al.Application of MRI and CTA fusion images combined with neuronavigation to transsphenoidal microsurgery for pituitary adenomas[J].,2015,(12):513.[doi:10.13798/j.issn.1009-153X.2015.09.001]
[14]王　璨　喻军华　黄锦峰　陈志勇　刘　斌　袁学刚　吴新宇.经鼻蝶入路显微手术切除垂体腺瘤36例[J].中国临床神经外科杂志,2015,(09):547.[doi:10.13798/j.issn.1009-153X.2015.09.012]
[15]苏卢海　张世渊　胡昌辰　沈　波.神经导航辅助内镜下经鼻蝶入路手术治疗垂体腺瘤的疗效观察[J].中国临床神经外科杂志,2015,(09):549.[doi:10.13798/j.issn.1009-153X.2015.09.013]
[16]龙贤明　刘华明　喻小平.垂体脓肿误诊为垂体腺瘤1例[J].中国临床神经外科杂志,2015,(01):64.[doi:10.13798/j.issn.1009-153X.2015.01.023]
[17]张文华　谢　蒙　王　旋　林敏华.内镜手术与显微手术治疗垂体瘤疗效的Meta分析[J].中国临床神经外科杂志,2015,(02):78.[doi:10.13798/j.issn.1009-153X.2015.02.004]
　ZHANG Wen-hua,XIE Meng,WANG Xuan,et al.Endoscopic surgery and microsurgery for pituitary adenomas: a Meta analysis[J].,2015,(12):78.[doi:10.13798/j.issn.1009-153X.2015.02.004]
[18]毋江 杨红利 解旭鹏 王甲光.经鼻蝶入路垂体腺瘤切除术后严重颅内感染合并脑积水2例[J].中国临床神经外科杂志,2017,(10):734.[doi:10.13792017.09/j.issn.1009-153X.2017.10.025]
[19]肖　瑾　王卫红　毛忠祥　程宏伟　王先祥　李志范　王　斌　张义泉.多种技术辅助切除伴复杂蝶窦的垂体腺瘤[J].中国临床神经外科杂志,2019,(02):102.[doi:10.13798/j.issn.1009-153X.2019.02.012]
[20]王建飞　石东付　卢国奇等.经鼻蝶入路神经内镜手术和显微手术治疗垂体腺瘤的疗效[J].中国临床神经外科杂志,2021,26(02):117.[doi:10.13798/j.issn.1009-153X.2021.02.017]

备注/Memo

备注/Memo:
doi:10.13798/j.issn.1009-153X.2018.12.011 作者单位：430060 武汉，武汉大学人民医院神经外科（连海伟、刘仁忠、简志宏、王　峻、易伟、杨振兴、刘　佳、王　雷）
更新日期/Last Update: 2018-12-26