[1]阿库布千、李祥龙、罗 鑫、周 江、李 昊、刘 亮、 陈礼刚、夏祥国.亚洲人群动脉瘤性蛛网膜下腔出血高压氧辅助治疗疗效的Meta分析[J].中国临床神经外科杂志,2017,(11):757-760.[doi:10.13798/j.issn.1009-153X.2017.11.008]
 AKU Bu-qian,LI Xiang-long,LUO Xin,et al.Meta-analysis of effects of hyperbaric oxygen therapy on clinical outcomes in Asian patients with aneurysmal subarachnoid hemorrhage[J].,2017,(11):757-760.[doi:10.13798/j.issn.1009-153X.2017.11.008]
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亚洲人群动脉瘤性蛛网膜下腔出血高压氧辅助治疗疗效的Meta分析()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2017年11期
页码:
757-760
栏目:
论著
出版日期:
2017-11-25

文章信息/Info

Title:
Meta-analysis of effects of hyperbaric oxygen therapy on clinical outcomes in Asian patients with aneurysmal subarachnoid hemorrhage
文章编号:
1009-153X(2017)11-0757-04
作者:
阿库布千、李祥龙、罗 鑫、周 江、李 昊、刘 亮、 陈礼刚、夏祥国
646000 泸州,西南医科大学附属医院神经外科(阿库布千、李祥龙、罗 鑫、周 江、李 昊、刘 亮、 陈礼刚、夏祥国) 通迅作者:夏祥国,E-mail:xxgsin@sina.com
Author(s):
AKU Bu-qian LI Xiang-long LUO Xin ZHOU Jiang LI Hao LIU liang CHEN Li-gang XIA Xiang-guo.
Department of Neurosurgery, Affiliated Hospital, Southwest Medical University, Luzhou 646000, China
关键词:
动脉瘤性蛛网膜下腔出血疗效高压氧治疗Meta分析
Keywords:
Aneurysmal subarachnoid hemorrhage Hyperbaric Oxygen therapyCurative effectPostoperative patients
分类号:
R 743.9; R 459.6
DOI:
10.13798/j.issn.1009-153X.2017.11.008
文献标志码:
A
摘要:
目的 综合评价亚洲人群动脉瘤性蛛网膜下腔出血(aSAH)高压氧(HBO)辅助治疗的临床疗效。方法 计算机检索Ovid、PubMed、MEDLINE、EBSCO及EMBASE等外文数据库,以及中国生物医学文献数据库、中国知网、万方数据库、维普数据库等中文数据库,检索从建库开始至2017 年2月发表的HBO辅助治疗aSAH的随机对照研究。采用RevMan 5.3进行统计分析。结果 纳入符合标准文献10篇,共856例aSAH。Meta分析结果显示:和对照组相比,HBO辅助治疗组GOS评分明显增高(RR=1.19,95%CI:1.04~1.36,P=0.010)、ADL评分明显增高(MD=-11.99,95%CI:-13.95~-10.3,P=0.00001)、Barthel指数明显增高(MD=12.42,95%CI:5.82~19.03,P=0.0002)、症状性血管痉挛发生率明显降低(RR=0.56,95%CI:0.41~0.78,P=0.0006<0.05)、治疗结束时大脑中动脉平均血流速度明显降低(MD=-10.07,95%CI:-16.33~-3.80,P=0.002)。结论 亚洲人群aSAH术后进行HBO辅助治疗可以改善病人预后。
Abstract:
Objective To evaluate the effects of hyperbaric oxygen therapy (HBOT) on clinical outcomes in the postoperative Asian patients with aneurysmal subarachnoid hemorrhage (aSAH). Methods Systematic literature retrieval from the data bases including Ovid, PubMed, MEDLINE, EBSCD and EMBASE was carried out to obtain randomized controlled trials of HBOT in the postoperative Asian patients with aSAH before February, 2017.Methodological quality assessment and data collection were performed by two individual reviewers, and Meta-analysis was performed with software RevMan 5.3. Results A total of 10 original articles about randomized controlled trails of HBOT including 856 postoperative patients with aSAH were derived from the above-mentioned data base. The Meta-analysis results showed that there are significant differences in the good prognosis according to GOS (RR=1.19, 95% CI: 1.04~1.36, P=0.010), activity of daily living scores (MD=-11.99, 95% CI: -13.95~-10.3, P=0.00001), Barthel index (MD=12.42, 95%CI: 5.82~19.03, P=0.0002), symptomatic vasospasm (RR=0.56, 95% CI: 0.41~0.78, P=0.0006), mean blood flow velocity of middle cerebral artery (MD=-10.07, 95% CI: -16.33~-3.80, P=0.002) between the HBOT group and control group. Conclusions According to the perspective of the existing clinical evidence, the prognoses may be improved by HBOT in the postoperative Asian patients with aSAH.

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备注/Memo

备注/Memo:
基金项目:四川省泸州市科技计划项目[2016-S-67(6/23)]
更新日期/Last Update: 2017-09-12