[1]鲍有园 吴 虓 丁 函等.巨大侵袭性泌乳素腺瘤溴隐亭治疗后并发脑脊液漏3例报道并文献复习[J].中国临床神经外科杂志,2021,26(11):862-865.[doi:10.13798/j.issn.1009-153X.2021.11.013]
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巨大侵袭性泌乳素腺瘤溴隐亭治疗后并发脑脊液漏3例报道并文献复习()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
26
期数:
2021年11期
页码:
862-865
栏目:
经验介绍
出版日期:
2021-11-25

文章信息/Info

文章编号:
1009-153X(2021)11-0862-04
作者:
鲍有园 吴 虓 丁 函等
330006 南昌,南昌大学第一附属医院神经外科(鲍有园、吴 虓、丁 函、洪 涛)
关键词:
巨大侵袭性泌乳素腺瘤溴隐亭脑脊液鼻漏经鼻蝶入路神经内镜手术
分类号:
R 739.41
DOI:
10.13798/j.issn.1009-153X.2021.11.013
文献标志码:
B
摘要:
目的 探讨巨大侵袭性泌乳素腺瘤溴隐亭治疗后发生脑脊液鼻漏的原因及治疗。方法 回顾性分析2015年3月到2019年12月收治的3例巨大侵袭性泌乳素腺瘤溴隐亭治疗后并发脑脊液鼻漏的临床资料。结果 3例均采用经鼻蝶入路神经内镜下垂体腺瘤部分切除+脑脊液漏修补术,其中2例因广泛颅底缺损术后予以腰大池置管引流。1例术后发生短暂性尿崩,另2例未发生与手术相关的并发症。出院后继续口服溴隐亭治疗,术后随访1~5年,均无脑脊液鼻漏、颅内感染,血清泌乳素水平逐渐降至正常,肿瘤体积明显缩小。结论 溴隐亭治疗巨大侵袭性泌乳素腺瘤有并发脑脊液鼻漏的风险,经鼻蝶入路神经内镜下肿瘤部分切除+脑脊液漏修补术是处理该罕见并发症一种较为有效的方法,既可防止该并发症上升为脑膜炎的风险,又可继续药物治疗。

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更新日期/Last Update: 1900-01-01