参考文献/References:
[1]刘宝辉,孙 前,袁凡恩,等. 高级别胶质瘤的治疗进展[J]. 中国临床神经外科杂志,2021,26(5):380-384.
[2]Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radio-therapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial [J]. Lancet Oncol, 2009, 10(5): 459-466.
[3]Stupp R, Taillibert S, Kanner AA, et al. Maintenance therapy with tumor-treating fields plus temozolomide vs temozolomide alone for glioblastoma: a randomized clinical trial [J]. JAMA, 2015, 314(23): 2535-2543.
[4]Goenka A, Tiek D, Song X, et al. The many facets of therapy resistance and tumor recurrence in glioblastoma [J]. Cells, 2021, 10(3): 484.
[5]Murugan AK. mTOR: role in cancer,metastasis and drug resistance [J]. Semin Cancer Biol, 2019, 59: 92-111.
[6]Ghosh S, Marrocco I, Yarden Y. Roles for receptor tyrosine kinases in tumor progression and implications for cancer treatment [J]. Adv Cancer Res, 2020, 147: 1-57.
[7]King JL, Zhang B, Li Y, et al. TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer [J]. Oncogenesis, 2018, 7(9): 69.
[8]Huang H, Yang Y, Zhang W, et al. TTK regulates proliferation and apoptosis of gastric cancer cells through the Akt-mTOR pathway [J]. FEBS Open Bio, 2020, 10(8): 1542-1549.
[9]Kaistha BP, Honstein T, Müller V, et al. Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells [J]. Br J Cancer, 2014, 111(9): 1780-1787.
[10]Chandler BC, Moubadder L, Ritter CL, et al. TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination [J]. J Clin Invest, 2020, 130(2): 958-973.
[11]Zhang H, Yao W, Zhang M, et al. TTK inhibitor promotes radiosensitivity of liver cancer cells through p21 [J]. Biochem Biophys Res Commun, 2021, 550: 84-91.
[12]Chen S, Wang J, Wang L, et al. Silencing TTK expression inhibits the proliferation and progression of prostate cancer [J]. Exp Cell Res, 2019, 385(1): 111669.
[13]Zhang N, Wei P, Gong A, et al. FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis [J]. Cancer Cell, 2011, 20(4): 427-442.
[14]Wang J, Yang T, Xu G, et al. Cyclin-dependent kinase 2 promotes tumor proliferation and induces radio resistance in glioblastoma [J]. Transl Oncol, 2016, 9(6): 548-556.
[15]Wang Q, Hu B, Hu X, et al. Tumor evolution of glioma-intrinsic gene expression subtypes associates with immuno-logical changes in the microenvironment [J]. Cancer Cell, 2017, 32(1): 42-56.
[16]Payne AW, Pant DK, Pan TC, et al. Ceramide kinase promotes tumor cell survival and mammary tumor recurrence [J]. Cancer Res, 2014, 74(21): 6352-6363.
[17]Liang XD, Dai YC, Li ZY, et al. Expression and function analysis of mitotic checkpoint genes identifies TTK as a potential therapeutic target for human hepatocellular carcinoma [J]. PLoS One, 2014, 9(6): e97739.
[18]Pachis ST, Kops GJPL. Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis [J]. Open Biol, 2018, 8(8): 180109.
[19]Karoulia Z, Gavathiotis E, Poulikakos PI. New perspectives for targeting RAF kinase in human cancer [J]. Nat Rev Cancer, 2017, 17(11): 676-691.
[20]Markham A,Keam SJ. Selumetinib: first approval [J]. Drugs, 2020, 80(9): 931-937.
[21]Stratford JK, Yan F, Hill RA, et al. Genetic and pharmaco-logical inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability [J]. PLoS One, 2017, 12(4): e0174863.
[22]Uitdehaag JCM, de Man J, Willemsen-Seegers N, et al. Target residence time-guided optimization on TTK kinase results in inhibitors with potent anti-proliferative activity [J]. J Mol Biol, 2017, 429(14): 2211-2230.
[23]Schulze VK, Klar U, Kosemund D, et al. Treating cancer by spindle assembly checkpoint abrogation: discovery of two clinical candidates, BAY 1161909 and BAY 1217389, targeting MPS1 kinase [J]. J Med Chem, 2020, 63(15): 8025-8042.
[24]Chen S, Wang Y, Ni C, et al. HLF/miR-132/TTK axis regulates cell proliferation, metastasis and radiosensitivity of glioma cells [J]. Biomed Pharmacother, 2016, 83: 898-904.
[25]Wang J, Xie Y, Bai X, et al. Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma [J]. Oncotarget, 2018, 9(3): 3081-3088.
相似文献/References:
[1]谢宝树 张 林 王 宇 贾 锋 殷玉华.复发性多发胶质母细胞瘤的预后分析[J].中国临床神经外科杂志,2016,(06):333.[doi:10.13798/j.issn.1009-153X.2016.06.005]
XIE Bao-shu,ZHANG Lin,WANG Yu,et al.Analysis of prognoses in patients with recurrent multiple glioblastomas[J].,2016,(10):333.[doi:10.13798/j.issn.1009-153X.2016.06.005]
[2]宋贵东 综述 高之宪 审校.贝伐单抗治疗复发胶质母细胞瘤的研究进展[J].中国临床神经外科杂志,2015,(10):638.[doi:10.13798/j.issn.1009-153X.2015.10.022]
[3]李继强 杨吉安 邵灵敏 吴庭枫 刘宝辉 陈谦学.稳定低表达BAG3的胶质母细胞瘤U87细胞株的构建及鉴定[J].中国临床神经外科杂志,2015,(06):353.[doi:10.13798/j.issn.1009-153X.2015.06.011]
LI Ji-qiang,YANG Ji-an,SHAO Ling-min,et al.Construction and identification of U87 glioblastoma cell strain with a stable low expression of BAG3[J].,2015,(10):353.[doi:10.13798/j.issn.1009-153X.2015.06.011]
[4]桂志勇 冯 军 黄俊红 白敬洋.靶向沉默c-fos基因表达对胶质瘤U87MG细胞增殖与侵袭的影响[J].中国临床神经外科杂志,2017,(12):834.[doi:10.13798/j.issn.1009-153X.2017.12.011]
GUI Zhi-yong,FENG Jun,HUANG Jun-hong,et al.Effects of c-fos targeted silence on proliferation and invasiveness of human glioma cell U87[J].,2017,(10):834.[doi:10.13798/j.issn.1009-153X.2017.12.011]
[5]王娇燕 孟凡华 刘魏然 魏春晓 林丽萍.SWI在胶质母细胞瘤与单发脑转移瘤鉴别中的价值[J].中国临床神经外科杂志,2018,(01):13.[doi:10.13798/j.issn.1009-153X.2018.01.005]
WANG Jiao-yan,MENG Fan-hua,LIU Wei-ran,et al.Value of susceptibility-weighted imaging in differentiative diagnosis of glioblastomas and solitary brain metastases[J].,2018,(10):13.[doi:10.13798/j.issn.1009-153X.2018.01.005]
[6]张治元 王汉东 樊友武 贾 玥 吴晋蓉.胶质肉瘤15例分析及文献复习[J].中国临床神经外科杂志,2018,(02):69.
ZHANG Zhi-yuan,WANG Han-dong,FAN You-wu,et al.Diagnosis and treatment of gliosarcoma: a report of 15 cases and literature review[J].,2018,(10):69.
[7]郑锐哲 姜秀峰 陈二涛 孙兆良 冯东福.胶质母细胞瘤卒中术后继发硬膜下水瘤1例[J].中国临床神经外科杂志,2019,(02):128.[doi:10.13798/j.issn.1009-153X.2019.02.022]
[8]胡 玥,薛小燕,李子超,等.阿苯达唑抑制胶质瘤裸鼠模型肿瘤生长[J].中国临床神经外科杂志,2019,(06):348.[doi:10.13798/j.issn.1009-153X.2019.06.010]
HU Yue,XUE Xiao-yan,LI Zi-chao,et al.Albendazole inhibits tumor growth in nude mice model of glioma[J].,2019,(10):348.[doi:10.13798/j.issn.1009-153X.2019.06.010]
[9]殷安安 陆 南 贺亚龙 章 翔 刘玉河.TRIM38基因非CpG岛DNA甲基化与胶质母细胞瘤临床预后的关系[J].中国临床神经外科杂志,2020,(02):76.[doi:10.13798/j.issn.1009-153X.2020.02.005]
YIN An-an,LU Nan,HE Ya-long,et al.Impacts of TRIM38 non-CpG island DNA methylation alterations on clinical prognosis in patients with glioblastomas[J].,2020,(10):76.[doi:10.13798/j.issn.1009-153X.2020.02.005]
[10]吴 蛟 易 勇 赵卓琳 周良学 周世军.贝伐珠单抗联合化疗治疗胶质母细胞瘤的meta分析[J].中国临床神经外科杂志,2020,(02):82.[doi:10.13798/j.issn.1009-153X.2020.02.007]
WU Jiao,YI Yong,ZHAO Zhuo-lin,et al.Efficacy and safety of bevacizumab combined with chemotherapy for glioblastoma: a meta-analysis[J].,2020,(10):82.[doi:10.13798/j.issn.1009-153X.2020.02.007]