[1]王亚东　陈谦学.生物型人工硬脑膜补片在颅脑损伤大骨瓣减压术中的应用[J].中国临床神经外科杂志,2015,(03):151-152.[doi:10.13798/j.issn.1009-153X.2015.03.007]
　WANG Ya-dong,CHEN Qian-xue..Use of biological artificial dura mater for tension relaxing suture of cerebral dura mater during large trauma craniotomy decompression in patients with traumatic brain injury[J].,2015,(03):151-152.[doi:10.13798/j.issn.1009-153X.2015.03.007]
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生物型人工硬脑膜补片在颅脑损伤大骨瓣减压术中的应用()
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《中国临床神经外科杂志》[ISSN:1009-153X/CN:42-1603/TN]

卷:
期数:
2015年03期
页码:
151-152
栏目:
论著
出版日期:
2015-03-30

文章信息/Info

Title:
Use of biological artificial dura mater for tension relaxing suture of cerebral dura mater during large trauma craniotomy decompression in patients with traumatic brain injury
文章编号:
1009-153X（2015）03-0151-02
作者:
王亚东　陈谦学
430060 武汉，武汉大学人民医院神经外科
Author(s):
WANG Ya-dong;  CHEN Qian-xue.
Department of Neurosurgery, Renmin Hospital, Wuhan University, Wuhan 430060, China
关键词:
颅脑损伤; 生物型人工硬脑膜; 大骨瓣减压术; 硬脑膜缺损
Keywords:
Biological artificial dura mater;  Traumatic brain injury;  Large trauma craniotomy;  Dura mater defect
分类号:
R 651.1+5; R 651.1+1
DOI:
10.13798/j.issn.1009-153X.2015.03.007
文献标志码:
A
摘要:
目的 探讨生物型人工硬脑膜补片在颅脑损伤大骨瓣减压术中的应用价值。方法 回顾性分析160例在颅脑损伤大骨瓣减压术中使用生物型人工硬脑膜补片修补硬脑膜治疗的患者的临床资料。结果 160例患者，存活148例，死亡12例。存活者中117例获半年以上随访，结果显示，患者手术伤口均未发生感染、切口漏和脑膨出等，伤口愈合良好；73例患者在术后3~6月行颅骨修补术，术中见皮瓣解剖层次清晰，粘连程度轻，皮瓣易于分离，分离过程中创面出血少，手术时间短，硬脑膜完整。结论 生物型人工硬脑膜组织相容性及致密性好，用其修补硬脑膜能够起到恢复硬脑膜解剖结构、保护脑组织的作用。
Abstract:
Objective To explore the curative effect of use the biological artificial dura mater during large traumatic craniotomy decompression in the patients with traumatic brain injury (TBI). Methods The clinical data of 160 patients with TBI, in whom the biological artificial dura mater was used for the tension relaxing suture of the cerebral dura mater during the large traumatic craniotomy decompression, were analyzed retrospectively, including the curative effect, postoperative complications and following up data. Results Of 160 patients with TBI, 148 survived and 12 died. One hundred and seventeen patients were follow-up for 1 year. The wound healed well, and wound infection, incision leakage of cerebrospinal fluid and encephalocole did not occurred in all the patients followed up. The clear anatomical structure of the skin flap, light adhesion of the tissues, skin flap easy to separate, less bleeding in the process of separation of the tissues, complete dura mater and shorter operative time were found when osteoplasty of skull was performed from 3 to 6 months after the decompression in 73 patients. Conclusions The biological artificial dura mater has the merits such as the stable biological properties, good histocompatibility and high compactness. The dura mater anatomical structure may be restored well and the cerebral tissues may be protected well when the biological artificial dura mater was used for the tesion relaxing suture of cerebral dura mater during the large trauma craniotomy decompression in the patients with TBI.

参考文献/References:

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更新日期/Last Update: 2015-03-30